中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
首页
机构
成果
学者
登录
注册
登陆
×
验证码:
换一张
忘记密码?
记住我
×
校外用户登录
CAS IR Grid
机构
上海药物研究所 [153]
化学研究所 [112]
长春应用化学研究所 [53]
上海生物化学与细胞... [52]
大连化学物理研究所 [43]
中国科学院大学 [39]
更多
采集方式
OAI收割 [698]
iSwitch采集 [48]
内容类型
期刊论文 [719]
学位论文 [19]
会议论文 [8]
发表日期
2022 [14]
2021 [26]
2020 [14]
2019 [25]
2018 [63]
2017 [35]
更多
学科主题
Biochemis... [33]
Chemistry [14]
Biochemis... [13]
Cell Biol... [10]
物理化学 [8]
Biophysics [7]
更多
筛选
浏览/检索结果:
共746条,第1-10条
帮助
条数/页:
5
10
15
20
25
30
35
40
45
50
55
60
65
70
75
80
85
90
95
100
排序方式:
请选择
提交时间升序
提交时间降序
发表日期升序
发表日期降序
题名升序
题名降序
作者升序
作者降序
Molecular basis of ClC-6 function and its impairment in human disease
期刊论文
OAI收割
SCIENCE ADVANCES, 2023, 卷号: 9, 期号: 41, 页码: 15
作者:
Zhang, Bing
;
Zhang, Sensen
;
Polovitskaya, Maya M.
;
Yi, Jingbo
;
Ye, Binglu
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/12/08
Biological Function of Pin1 in Vivo and Its Inhibitors for Preclinical Study: Early Development, Current Strategies, and Future Directions
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 14, 页码: 9251-9277
作者:
He, Siyu
;
Li, Linjie
;
Jin, Rui
;
Lu, Xiaojie
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2023/10/17
Triterpenoids with multi-skeletons as 11 beta-HSD1 inhibitors from Euphorbia sikkimensis
期刊论文
OAI收割
PHYTOCHEMISTRY, 2023, 卷号: 211, 页码: 12
作者:
Fang, Chu-Hong
;
Li, Yu-Peng
;
Li, Ying
;
Yue, Jian-Min
;
Bao, Jie
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/10/17
Euphorbia sikkimensis family
Triterpenoids
11fl-HSD1 inhibitors
Molecular docking
Metabolic abnormalities
Conformational Dynamics of the D53-D3-D14 Complex in Strigolactone Signaling
期刊论文
OAI收割
PLANT AND CELL PHYSIOLOGY, 2023, 页码: 11
作者:
Liu, Simiao
;
Wang, Jia
;
Song, Bin
;
Gong, Xinqi
;
Liu, Huihui
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2023/10/17
D3
D14
D53
Receptor complex
Signal transduction
Strigolactone
A RhoA structure with switch II flipped outward revealed the conformational dynamics of switch II region
期刊论文
OAI收割
JOURNAL OF STRUCTURAL BIOLOGY, 2023, 卷号: 215, 期号: 2, 页码: 107942
作者:
Jiang, Hao
;
Zu, Shijia
;
Lu, Yu
;
Sun, Zhongya
;
Adeerjiang, Akejiang
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2024/03/27
Small GTPases
Crystal structures of RhoA
Dynamics of switch II
Molecular dynamics simulations
Allosteric pocket
Modular Biomimetic Strategy Enabled Discovery of Simplified Pseudo-Natural Macrocyclic P-Glycoprotein Inhibitors Capable of Overcoming Multidrug Resistance
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 4, 页码: 2550-2565
作者:
Liu, Bo
;
Yu, Xueni
;
Liu, Liping
;
Wang, Lei
;
Wang, Jie
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/03/27
Discovery of 10H-Benzo[b]pyrido[2,3-e][1,4]oxazine AXL Inhibitors via Structure-Based Drug Design Targeting c-Met Kinase
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 页码: 15
作者:
Zhan, Zhengsheng
;
Ji, Yinchun
;
Su, Haixia
;
Fang, Chen
;
Peng, Xia
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2023/04/10
Structural insights into a shared mechanism of human STING activation by a potent agonist and an autoimmune disease-associated mutation
期刊论文
OAI收割
CELL DISCOVERY, 2022, 卷号: 8, 期号: 1, 页码: 17
作者:
Xie, Zuoquan
;
Wang, Zhen
;
Fan, Fengying
;
Zhou, Jinpei
;
Hu, Zhaoxue
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2023/04/10
Fine Pore-Structure Engineering by Ligand Conformational Control of Naphthalene Diimide-Based Semiconducting Porous Coordination Polymers for Efficient Chemiresistive Gas Sensing
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2022, 页码: 6
作者:
Xue, Ziqian
;
Zheng, Jia-Jia
;
Nishiyama, Yusuke
;
Yao, Ming-Shui
;
Aoyama, Yoshitaka
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2023/02/24
PCPs
MOFs
NDI
Semiconductors
Sensors
3D electron diffraction (3D ED)
A spectroscopic approach to identifying the out-of-plane conformations of Ni(II) meso-tetraphenylporphyrin in solution
期刊论文
OAI收割
JOURNAL OF MOLECULAR STRUCTURE, 2022, 卷号: 1269
作者:
Wang, Shenhao
;
Huang, Qing
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2022/12/23
NiTPP
Out-of-plane deformations
DFT
Molecular dynamics
Raman spectroscopy
1 H-NMR