中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海营养与健康研究... [12]
上海药物研究所 [9]
深圳先进技术研究院 [2]
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期刊论文 [28]
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Development of the novel ACLY inhibitor 326E as a promising treatment for hypercholesterolemia
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 2, 页码: 739-753
作者:
Xie, Zhifu
;
Zhang, Mei
;
Song, Qian
;
Cheng, Long
;
Zhang, Xinwen
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/03/27
Hypercholesterolemia
Atherosclerosis
Liver
ATP-Citrate lyase (ACLY)
Lipogenesis
Cholesterol efflux
ACLY inhibitor
7-aminocephalosporanic acid, a novel HSP90 beta inhibitor, attenuates HFD-induced hepatic steatosis
期刊论文
OAI收割
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2022, 卷号: 622, 页码: 184-191
作者:
Zhang, Weitao
;
Xue, Hanyue
;
Zhou, Chen
;
Zheng, Zuguo
;
Xing, Mingming
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2022/12/13
7-aminocephalosporanic acid
HSP90 beta
NAFLD
de novo lipogenesis
SPR
Forrestiacids C and D, unprecedented triterpene-diterpene adducts from Pseudotsuga forrestii
期刊论文
OAI收割
CHINESE CHEMICAL LETTERS, 2022, 卷号: 33, 期号: 9, 页码: 4264-4268
作者:
Zhou, Peng-Jun
;
Zang, Yi
;
Li, Cong
;
Yuan, Lin
;
Zeng, Huaqiang
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2022/08/16
Forrestiacid
Pseudotsuga forrestii
Pinaceae
Michael adduct
Lipogenesis inhibitor
3-tert-Butyl-4-hydroxyanisole Impairs Hepatic Lipid Metabolism in Male Mice Fed with a High-Fat Diet
期刊论文
OAI收割
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2022, 卷号: 56, 期号: 5, 页码: 3204-3213
作者:
Sun, Zhendong
;
Tang, Zhi
;
Yang, Xiaoxi
;
Liu, Qian S.
;
Zhang, Jianqing
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2022/11/08
SYNTHETIC PHENOLIC ANTIOXIDANTS
LIVER-DISEASE
EXPOSURE
HOMEOSTASIS
Forrestiacids A and B, Pentaterpene Inhibitors of ACL and Lipogenesis: Extending the Limits of Computational NMR Methods in the Structure Assignment of Complex Natural Products
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 页码: 7
作者:
Xiong, Juan
;
Zhou, Peng-Jun
;
Jiang, Hao-Wen
;
Huang, Ting
  |  
收藏
  |  
浏览/下载:103/0
  |  
提交时间:2021/11/04
forrestiacids
lipogenesis inhibitors
natural products
structure elucidation
terpenoids
Lipid Disorders in NAFLD and Chronic Kidney Disease
期刊论文
OAI收割
BIOMEDICINES, 2021, 卷号: 9, 期号: 10, 页码: 1405
作者:
Yang,Meng
;
Geng,Chang-An
;
Liu,Xinguang
;
Guan,Min
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2022/04/02
lipid
NAFLD
chronic kidney disease
NONALCOHOLIC FATTY LIVER
ENDOPLASMIC-RETICULUM STRESS
MESENCHYMAL STEM-CELLS
INSULIN-RESISTANCE
LIPOPROTEIN METABOLISM
OBETICHOLIC ACID
RENAL-FIBROSIS
RECEPTOR-ALPHA
MOUSE MODEL
ER STRESS
4-Hexylphenol influences adipogenic differentiation and hepatic lipid accumulation in vitro
期刊论文
OAI收割
ENVIRONMENTAL POLLUTION, 2021, 卷号: 268, 页码: -
作者:
Sun, Zhendong
;
Cao, Huiming
;
Liu, Qian S.
;
Liang, Yong
;
Fiedler, Heidelore
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2021/12/22
Obesity
Estrogen receptor
Nonalcoholic fatty liver disease
Adipogenesis
Lipogenesis
Exploring the Impact of a Low-Protein High-Carbohydrate Diet in Mature Broodstock of a Glucose-Intolerant Teleost, the Rainbow Trout
期刊论文
OAI收割
FRONTIERS IN PHYSIOLOGY, 2020, 卷号: 11, 页码: 21
作者:
Callet, Therese
;
Hu, Huihua
;
Larroquet, Laurence
;
Surget, Anne
;
Liu, Jingwei
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2020/09/14
liver
gonad
enzymatic activity
glucose metabolism
pentose phosphate pathway
glycogen
male
female
Post-translational regulation of lipogenesis via AMPK-dependent phosphorylation of insulin-induced gene
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2019, 卷号: 10, 页码: 13
作者:
Han, Yamei
;
Hu, Zhimin
;
Cui, Aoyuan
;
Liu, Zhengshuai
;
Ma, Fengguang
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2020/07/01
Inhibition of HSP90 beta Improves Lipid Disorders by Promoting Mature SREBPs Degradation via the Ubiquitin-proteasome System
期刊论文
OAI收割
THERANOSTICS, 2019, 卷号: 9, 期号: 20, 页码: 5769-5783
作者:
Zheng, Zu-Guo
;
Zhang, Xin
;
Liu, Xiao-Xiao
;
Jin, Xiu-Xiu
;
Dai, Lunzhi
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2020/07/01
HSP90 beta
lipid metabolism
corylin
SREBPs
proteasomal degradation