中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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浏览/检索结果: 共44条,第1-10条 帮助

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Antinociceptive activities and mechanism of action of Cepharanthine 期刊论文  OAI收割
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2022, 卷号: 614, 页码: 219-224
作者:  
Wei, Xiang-Yan;  Long, Jian-Dong;  Chai, Jing-Rui;  Chen, Jing;  Gao, Jian-Ping
  |  收藏  |  浏览/下载:17/0  |  提交时间:2022/08/16
Exploration of the SAR Connection between Morphinan- and Arylacetamide-Based kappa Opioid Receptor (kappa OR) Agonists Using the Strategy of Bridging 期刊论文  OAI收割
ACS CHEMICAL NEUROSCIENCE, 2021, 卷号: 12, 期号: 6, 页码: 1018-1030
作者:  
Liu, Xiao;  Jiang, Shuang;  Kong, Linghui;  Ye, Rongrong;  Xiao, Li
  |  收藏  |  浏览/下载:83/0  |  提交时间:2021/05/24
Label-free cell phenotypic study of opioid receptors and discovery of novel mu opioid ligands from natural products 期刊论文  OAI收割
JOURNAL OF ETHNOPHARMACOLOGY, 2021, 卷号: 270, 页码: 113872
作者:  
Hou,Tao;  Xu,Fangfang;  Peng,Xingrong;  Zhou,Han;  Zhang,Xiuli
  |  收藏  |  浏览/下载:53/0  |  提交时间:2022/04/02
Uncovering kappa-opioid receptor agonist-induced PAK1/2 phosphorylation by quantitative phosphoproteomics 期刊论文  OAI收割
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2019, 卷号: 516, 期号: 1, 页码: 320-326
作者:  
Wu, Jianhong;  Jiang, Qinghui;  Zhu, Hongwen;  Zhou, Yanting;  Lu, Dayun
  |  收藏  |  浏览/下载:24/0  |  提交时间:2020/07/01
How Does Agonist and Antagonist Binding Lead to Different Conformational Ensemble Equilibria of the kappa-Opioid Receptor: Insight from Long-Time Gaussian Accelerated Molecular Dynamics Simulation 期刊论文  OAI收割
ACS CHEMICAL NEUROSCIENCE, 2019, 卷号: 10, 期号: 3, 页码: 1575-1584
作者:  
An, Xiaoli;  Bai, Qifeng;  Bing, Zhitong;  Zhou, Shuangyan;  Shi, Danfeng
  |  收藏  |  浏览/下载:57/0  |  提交时间:2019/11/10
Pharmacological Characterization of Dezocine, a Potent Analgesic Acting as a kappa Partial Agonist and mu Partial Agonist 期刊论文  OAI收割
SCIENTIFIC REPORTS, 2018, 卷号: 8
作者:  
Wang, Yu-Hua;  Chai, Jing-Rui;  Xu, Xue-Jun;  Ye, Ru-Feng;  Zan, Gui-Ying
  |  收藏  |  浏览/下载:89/0  |  提交时间:2019/01/08
7 beta-Methyl substituent is a structural locus associated with activity cliff for nepenthone analogues 期刊论文  OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 14, 页码: 4254-4263
作者:  
Sun, Hui-jiao;  Wang, Yu-hua;  Yuan, Cong-min;  Kong, Ling-hui;  Xu, Xue-jun
  |  收藏  |  浏览/下载:79/0  |  提交时间:2019/01/08
Computational insights into the subtype selectivity and "message-address-efficacy" mechanisms of opioid receptors through JDTic binding and unbinding 期刊论文  OAI收割
ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 3, 页码: 482-491
作者:  
Cheng, Jian-xin;  Cheng, Tao;  Li, Wei-hua;  Liu, Gui-xia;  Zhu, Wei-liang
  |  收藏  |  浏览/下载:15/0  |  提交时间:2019/01/08
GPCR Activation and Endocytosis Induced by a 2D Material Agonist 期刊论文  OAI收割
ACS APPLIED MATERIALS & INTERFACES, 2017, 卷号: 9, 期号: 17, 页码: 14709-14715
作者:  
Dou, Wei-Tao;  Kong, Ya;  He, Xiao-Peng;  Chen, Guo-Rong;  Zang, Yi
  |  收藏  |  浏览/下载:18/0  |  提交时间:2019/01/08
The anxiolytic- and antidepressant-like effects of ATPM-ET, a novel kappa agonist and mu partial agonist, in mice 期刊论文  OAI收割
PSYCHOPHARMACOLOGY, 2016, 卷号: 233, 期号: 12, 页码: 2411-2418
作者:  
Wang, Qian;  Long, Yu;  Hang, Ai;  Zan, Gui-Ying;  Shu, Xiao-Hong
  |  收藏  |  浏览/下载:22/0  |  提交时间:2019/01/08