中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [198]
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上海生物化学与细胞... [46]
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期刊论文 [702]
学位论文 [21]
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2024 [4]
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Oncology [23]
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Prognostic biomarker discovery based on proteome landscape of Chinese lung adenocarcinoma
期刊论文
OAI收割
CLINICAL PROTEOMICS, 2024, 卷号: 21, 期号: 1, 页码: 11
作者:
Huang, Yuqi
;
Ma, Sheng
;
Xu, Jun-Yu
;
Qian, Kun
;
Wang, Yaru
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2024/02/19
Lung adenocarcinoma
Proteome
Benign lung disease cases
Solid pathological subtype
Prognostic biomarker
Discovery of GPX4 inhibitors through FP-based high-throughput screening
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 265, 页码: 14
作者:
Cao, Yu
;
Wu, Bin
;
Xu, Ying
;
Wang, Mingchen
;
Wu, Xinyu
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2024/02/27
GPX4 inhibitor
HTS assay
Ferroptosis
Fluorescence polarization
JC-010a, a novel selective SHP2 allosteric inhibitor, overcomes RTK/non-RTK-mediated drug resistance in multiple oncogene-addicted cancers
期刊论文
OAI收割
CANCER LETTERS, 2024, 卷号: 582, 页码: 15
作者:
Lu, Xuxiu
;
Yu, Rilei
;
Li, Zhen
;
Yang, Mengke
;
Dai, Jiajia
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/04/07
Acquired resistance
Cancer
NSCLC
JC-010a
SHP2
Second messenger 2'3'-cyclic GMP-AMP (2'3'-cGAMP): the cell autonomous and non-autonomous roles in cancer progression
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 10
作者:
Ma, Xiao-yu
;
Chen, Man-man
;
Meng, Ling-hua
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2024/02/27
CDNs
2'3'-cGAMP
cGAS-STING
tumor microenvironment
ENPP1
TREX1
Epigenetic-based combination therapy and liposomal codelivery overcomes osimertinib-resistant NSCLC via repolarizing tumor-associated macrophages
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 12
作者:
Lin, Ting-ting
;
Xiong, Wei
;
Chen, Gui-hua
;
He, Yang
;
Long, Li
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2024/01/26
osimertinib resistance
targeted drug delivery
liposomes
panobinostat
tumor-associated macrophage
combination therapy
Physiological and Pathological Functions of TRPM7 Channel and Its Small-molecule Modulators
期刊论文
OAI收割
PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS, 2023, 卷号: 50, 期号: 12, 页码: 2856-2868
作者:
Wang, Yun-Qi
;
Guan, Zi-Yue
;
Gao, Zhao-Bing
;
Zheng, Yue-Ming
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/04/09
TRPM7
ion channel
physiological function
disease
small molecule modulators
Exosomes: New Insights into the Pathogenesis of Metabolic Syndrome
期刊论文
OAI收割
BIOLOGY-BASEL, 2023, 卷号: 12, 期号: 12, 页码: 14
作者:
Wang, Ning
;
Li, Jing
;
Hu, Zixuan
;
Ngowi, Ebenezeri Erasto
;
Yan, Baolong
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/02/27
exosome
biogeneration
function
metabolic syndrome
Molecular imaging-guided extracellular vesicle-based drug delivery for precise cancer management: Current status and future perspectives
期刊论文
OAI收割
JOURNAL OF CONTROLLED RELEASE, 2023, 卷号: 362, 页码: 97-120
作者:
Cheng, Zhongquan
;
Shang, Jihuan
;
Wang, Huarong
;
Yu, Leyi
;
Yuan, Zhu
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/11/16
Extracellular vesicles
Molecular imaging
Cancer
Diagnosis
Therapy
LINC00955 suppresses colorectal cancer growth by acting as a molecular scaffold of TRIM25 and Sp1 to Inhibit DNMT3B-mediated methylation of the PHIP promoter
期刊论文
OAI收割
BMC CANCER, 2023, 卷号: 23, 期号: 1, 页码: 20
作者:
Ren, Ganglin
;
Li, Hongyan
;
Hong, Dan
;
Hu, Fangyu
;
Jin, Rongjia
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2023/12/08
LINC00955
Colorectal cancer
Cell cycle
CDK2
PHIP
Sp1
Otilonium Bromide acts as a selective USP28 inhibitor and exhibits cytotoxic activity against multiple human cancer cell lines
期刊论文
OAI收割
BIOCHEMICAL PHARMACOLOGY, 2023, 卷号: 215, 页码: 14
作者:
Xu, Zhuo
;
Wang, Hui
;
Meng, Qian
;
Ding, Yiluan
;
Zhu, Mengying
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/10/17
Otilonium Bromide
Deubiquitinase
USP28
Selective inhibitor