中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [256]
采集方式
OAI收割 [256]
内容类型
期刊论文 [256]
发表日期
2017 [256]
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发表日期:2017
专题:上海药物研究所
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Pyrrolidine Dithiocarbamate (PDTC) Attenuates Cancer Cachexia by Affecting Muscle Atrophy and Fat Lipolysis
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2017, 卷号: 8
作者:
Miao, Chunxiao
;
Lv, Yuanyuan
;
Zhang, Wanli
;
Chai, Xiaoping
;
Feng, Lixing
  |  
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2019/01/08
cancer cachexia
PDTC
C2C12 myotubes
3T3-L1 adipocytes
muscle atrophy
fat lipolysis
Pharmacologic characterization of SHR8443, a novel dual inhibitor of phosphatidylinositol 3-kinase and mammalian target of rapamycin
期刊论文
OAI收割
ONCOTARGET, 2017, 卷号: 8, 期号: 64, 页码: 107977-107990
作者:
Xie, Chengying
;
Chen, Xiangling
;
Zheng, Mingyue
;
Liu, Xiaohong
;
Wang, Hongbin
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2019/01/08
BEZ235
drug resistance
mTOR
PI3K
SHR8443
Synthesis and biological evaluation of novel 4,5-bisindolyl-1,2,4-triazol-3-ones as glycogen synthase kinase-3 beta inhibitors and neuroprotective agents
期刊论文
OAI收割
PHARMAZIE, 2017, 卷号: 72, 期号: 12, 页码: 707-713
作者:
Hu, Yuanyuan
;
Ruan, Wenchen
;
Gao, Anhui
;
Zhou, Yubo
;
Gao, Lixin
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2019/01/08
Hypoxia induces universal but differential drug resistance and impairs anticancer mechanisms of 5-fluorouracil in hepatoma cells
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 12, 页码: 1642-1654
作者:
Li, Jing-qiu
;
Wu, Xian
;
Gan, Lu
;
Yang, Xiang-liang
;
Miao, Ze-hong
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2019/01/08
hepatocellular carcinoma
hypoxia
5-fluorouracil
sorafenib
drug resistance
Co-delivery of docetaxel and silibinin using pH-sensitive micelles improves therapy of metastatic breast cancer
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 12, 页码: 1655-1662
作者:
Dong, Xin-yue
;
Lang, Tian-qun
;
Yin, Qi
;
Zhang, Peng-cheng
;
Li, Ya-ping
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2019/01/08
pH-sensitive polymer
co-delivery
micelle
docetaxel
silibinin
breast cancer
mouse breast cancer cell line 4T1
metastasis
Discovery of a novel calcium-sensitive fluorescent probe for alpha-ketoglutarate
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 12, 页码: 1683-1690
作者:
Gan, Lin-lin
;
Chen, Lin-hai
;
Nan, Fa-jun
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/01/08
nonalcoholic fatty liver disease
biomarker
alpha-ketoglutarate
fluorescent probe
calcium-sensitive
benzothiazole-coumarin
6-Methoxyethylamino-numonafide inhibits hepatocellular carcinoma xenograft growth as a single agent and in combination with sorafenib
期刊论文
OAI收割
FASEB JOURNAL, 2017, 卷号: 31, 期号: 12, 页码: 5453-5465
作者:
Liu, Yanning
;
Lou, Guohua
;
Norton, John T.
;
Wang, Chen
;
Kandela, Irawati
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2019/01/08
MEAN
HCC therapeutic
combination treatment
C-MYC inhibition
An ultrasensitive fluorogenic probe for revealing the role of glutathione in chemotherapy resistance
期刊论文
OAI收割
CHEMICAL SCIENCE, 2017, 卷号: 8, 期号: 12, 页码: 8012-8018
作者:
Jiang, Yuejing
;
Cheng, Juan
;
Yang, Chengyu
;
Hu, Yongzhou
;
Li, Jia
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2019/01/08
Discovery of alkyl bis(oxy)dibenzimidamide derivatives as novel protein arginine methyltransferase 1 (PRMT1) inhibitors
期刊论文
OAI收割
CHEMICAL BIOLOGY & DRUG DESIGN, 2017, 卷号: 90, 期号: 6, 页码: 1260-1270
作者:
Zhang, Wei-yao
;
Lu, Wen-chao
;
Jiang, Hao
;
Lv, Zheng-bing
;
Xie, Yi-qian
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2019/01/08
epigenetics
molecular docking
PRMT1
scaffold hopping
small-molecule inhibitor
Reprogramming Tumor-Associated Macrophages To Reverse EGFR(T790M) Resistance by Dual-Targeting Codelivery of Gefitinib/Vorinostat
期刊论文
OAI收割
NANO LETTERS, 2017, 卷号: 17, 期号: 12, 页码: 7684-7690
作者:
Peng, Huige
;
Chen, Binfan
;
Huang, Wei
;
Tang, Yubo
;
Jiang, Yifan
  |  
收藏
  |  
浏览/下载:65/0
  |  
提交时间:2019/01/08
Tumor-associated macrophages
gefitinib
vorinostat
EGFR(T790M)
nonsmall cell lung cancer
drug resistance