中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [18]
过程工程研究所 [1]
海洋研究所 [1]
重庆绿色智能技术研究... [1]
合肥物质科学研究院 [1]
兰州化学物理研究所 [1]
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OAI收割 [23]
内容类型
期刊论文 [23]
发表日期
2022 [23]
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发表日期:2022
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Design and synthesis of chromone-nitrogen mustard derivatives and evaluation of anti-breast cancer activity
期刊论文
OAI收割
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2022, 卷号: 37, 期号: 1, 页码: 431-444
作者:
Sun, Jianan
;
Mu, Jiahui
;
Wang, Shenglin
;
Jia, Cai
;
Li, Dahong
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2022/06/15
Chromone
nitrogen mustard
breast cancer
apoptosis
Discovery of Highly Potent Nicotinamide Phosphoribosyltransferase Degraders for Efficient Treatment of Ovarian Cancer
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 页码: 15
作者:
Bi, Kaijian
;
Cheng, Junfei
;
He, Shipeng
;
Fang, Yuxin
;
Huang, Min
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2023/04/10
Design, synthesis, and biological evaluation of Wee1 kinase degraders
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 243, 页码: 21
作者:
Zhu, Shulei
;
Liu, Jieyu
;
Xiao, Donghuai
;
Wang, Peipei
;
Ma, Jingkun
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2022/11/11
CRBN
Wee1
PROTAC
Degradation
Cyclopiumolides A and B, unusual 13-membered macrolides from the deep sea-sourced fungus Penicillium cyclopium SD-413 with antiproliferative activities
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2022, 卷号: 128, 页码: 7
作者:
Li, Yan-He
;
Yang, Sui-Qun
;
Li, Xiao-Ming
;
Li, Xin
;
Wang, Bin-Gui
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2023/01/06
Macrolides
Penicillium cyclopium
Deep-sea sediment
Cytotoxicity
SOMCL-19-133, a novel, selective, and orally available inhibitor of NEDD8-activating enzyme (NAE) for cancer therapy
期刊论文
OAI收割
NEOPLASIA, 2022, 卷号: 32, 页码: 12
作者:
Zhou, Li-Na
;
Xiong, Chaodong
;
Cheng, Yong-Jun
;
Song, Shan-Shan
;
Bao, Xu-Bin
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2023/04/10
SOMCL-19-133
NAE inhibitor
MLN4924
NEDD8
Oral administration
Design, Synthesis, and Biological Evaluation of Androgen Receptor Degrading and Antagonizing Bifunctional Steroidal Analogs for the Treatment of Advanced Prostate Cancer
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 页码: 22
作者:
Wang, Ao
;
Luo, Xianggang
;
Wang, Yawan
;
Meng, Xin
;
Lu, Zhengyu
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2022/11/11
Synthesis of Hydantoin Androgen Receptor Antagonists and Study on Their Antagonistic Activity
期刊论文
OAI收割
MOLECULES, 2022, 卷号: 27, 期号: 18, 页码: 22
作者:
Ma, Longjun
;
Zhou, Yan
;
Yang, Dehua
;
Wang, Ming-Wei
;
Lu, Wei
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2022/11/11
androgen receptor
antagonist
enzalutamide
hydantoin analogs
antiproliferative
Integrating UPLC-HR-MS/MS, Network Pharmacology, and Experimental Validation to Uncover the Mechanisms of Jin?gan Capsules against Breast Cancer br
期刊论文
OAI收割
ACS OMEGA, 2022, 卷号: 7, 期号: 32, 页码: 28003-28015
作者:
Qiu, Jianfei
;
Zhang, Zhiyin
;
Hu, Anling
;
Zhao, Peng
;
Wei, Xuenai
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2022/09/30
Sheep tail fat inhibits the proliferation of non-small-cell lung cancer cells in vitro and in vivo
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13
作者:
Xu, Changzhi
;
Zhang, Lanlan
;
He, Huimin
;
Liu, Xiaoyi
;
Pei, Xinxin
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2022/12/23
sheep tail fat
non-small-cell lung cancer
heptadecanoic acid
antiproliferative effect
Akt
S6K signaling pathway
Integrating UPLC-HR-MS/MS, Network Pharmacology, and Experimental Validation to Uncover the Mechanisms of Jin'gan Capsules against Breast Cancer
期刊论文
OAI收割
ACS OMEGA, 2022, 页码: 13
作者:
Qiu, Jianfei
;
Zhang, Zhiyin
;
Hu, Anling
;
Zhao, Peng
;
Wei, Xuenai
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2022/09/30