中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [18]
心理研究所 [2]
西北高原生物研究所 [1]
过程工程研究所 [1]
海洋研究所 [1]
自动化研究所 [1]
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OAI收割 [25]
内容类型
期刊论文 [24]
学位论文 [1]
发表日期
2023 [25]
学科主题
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发表日期:2023
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CA1中央区NMDA受体G1uN3A亚基参与应激致抑郁和D-serine杭抑郁的细胞和环路机制
学位论文
OAI收割
中国科学院心理研究所: 中国科学院大学, 2023
作者:
张伟
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/01/05
抑郁相关行为
NMDA受体G1uN3A亚基
海马CA1
锥体神经元
D一丝氨酸
Structure-based drug discovery of novel fused- pyrazolone carboxamide derivatives as potent and selective AXL inhibitors
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 12, 页码: 4918-4933
作者:
Fang, Feifei
;
Dai, Yang
;
Wang, Hao
;
Ji, Yinchun
;
Liang, Xuewu
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/01/26
derivatives
Antitumor drug development
Potential AXL inhibitor
Antitumor activity
Structure-based drug design
Fused-pyrazolone carboxamide
Molecular characteristics of
IGF
and
IGF1R
genes and their potential roles on longevity in two scallops with distinct lifespans
期刊论文
OAI收割
AQUACULTURE REPORTS, 2023, 卷号: 33, 页码: 14
作者:
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/01/26
Argopecten scallops
IGF
IGF1R
Longevity
Gene expression
Nutrition restriction
Ionizing radiation
Physiological and Pathological Functions of TRPM7 Channel and Its Small-molecule Modulators
期刊论文
OAI收割
PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS, 2023, 卷号: 50, 期号: 12, 页码: 2856-2868
作者:
Wang, Yun-Qi
;
Guan, Zi-Yue
;
Gao, Zhao-Bing
;
Zheng, Yue-Ming
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/04/09
TRPM7
ion channel
physiological function
disease
small molecule modulators
Development of a novel
18
F-labeled small molecule probe for PET imaging of mesenchymal epithelial transition receptor expression
期刊论文
OAI收割
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2023, 页码: 13
作者:
Bu, Lihong
;
Ma, Xiaowei
;
Ji, Aiyan
;
Geng, Kaijun
;
Feng, Hongyan
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2023/12/19
Mesenchymal epithelial transition receptor
Gliomas
[18F]-AZC
PET
Quinoline derivative compound
Deubiquitylating Enzymes in Cancer and Immunity
期刊论文
OAI收割
ADVANCED SCIENCE, 2023, 页码: 37
作者:
Ren, Jiang
;
Yu, Peng
;
Liu, Sijia
;
Li, Ran
;
Niu, Xin
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2023/12/08
cancer
deubiquitylating enzymes (DUBs)
immunity
therapeutic approach
Elucidation of N-/O-glycosylation and site-specific mapping of sialic acid linkage isomers of SARS-CoV-2 human receptor angiotensin-converting enzyme 2
期刊论文
OAI收割
ANALYST, 2023, 卷号: 148, 期号: 20, 页码: 5002-5011
作者:
Wei, Liming
;
Chen, Yuning
;
Feng, Xiaoxiao
;
Yao, Jun
;
Zhang, Lei
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2023/12/08
Discovery of a highly potent NPAS3 heterodimer inhibitor by covalently modifying ARNT
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2023, 卷号: 139, 页码: 10
作者:
Li, Peizhuo
;
Tian, Yucheng
;
Shang, Qinghong
;
Tang, Cailing
;
Hou, Zeng
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2023/10/17
NPAS3
Covalent inhibitor
Protein -protein interaction
5-nitrothiazole warhead
Breaking Tumor Immunosuppressive Network by Regulating Multiple Nodes with Triadic Drug Delivery Nanoparticles
期刊论文
OAI收割
ACS NANO, 2023, 卷号: 17, 期号: 18, 页码: 17826-17844
作者:
Yan, Wenlu
;
Li, Yu
;
Zou, Yiting
;
Zhu, Runqi
;
Wu, Ting
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/12/08
triple-negative breast cancer
antitumor immunity
tumor-associated macrophages
myeloid-derived suppressorcells
immune network
nanoparticle
Discovery, structural optimization, and anti-tumor bioactivity evaluations of betulinic acid derivatives as a new type of ROR & gamma; antagonists
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 257, 页码: 15
作者:
Mei, Lianghe
;
Xu, Lansong
;
Wu, Sanan
;
Wang, Yafang
;
Xu, Chao
  |  
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2023/10/17
Betulinic acid
ROR & gamma
Target identification
Rationale structure optimization
Anti-tumor effects
antagonists