机构

• 上海药物研究所 [36]
• 海洋研究所 [7]
• 过程工程研究所 [4]
• 深海科学与工程研究所 [4]
• 金属研究所 [1]
• 合肥物质科学研究院 [1]
• 更多

采集方式

• OAI收割 [54]

内容类型

• 期刊论文 [51]
• 学位论文 [3]

发表日期

• 2023 [54]

学科主题

筛选

浏览/检索结果: 共54条，第1-10条 帮助 限定条件 发表日期：2023     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Discovery of JN122, a Spiroindoline-Containing Molecule that Inhibits MDM2/p53 Protein-Protein Interaction and Exerts Robust In Vivo Antitumor Efficacy 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 24, 页码: 16991-17025 作者:  Cheng, Jing;  Yan, Ziqin;  Jiang, Kailong;  Liu, Chen;  Xu, Dehua   |  收藏  |  浏览/下载：5/0  |  提交时间：2024/02/19 Structure-based drug discovery of novel fused- pyrazolone carboxamide derivatives as potent and selective AXL inhibitors 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 12, 页码: 4918-4933 作者:  Fang, Feifei;  Dai, Yang;  Wang, Hao;  Ji, Yinchun;  Liang, Xuewu   |  收藏  |  浏览/下载：7/0  |  提交时间：2024/01/26 derivatives  Antitumor drug development  Potential AXL inhibitor  Antitumor activity  Structure-based drug design  Fused-pyrazolone carboxamide   Discovery of PVD-06 as a Subtype-Selective and Efficient PTPN2 Degrader 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 22, 页码: 15269-15287 作者:  Hu, Linghao;  Li, Huiyun;  Qin, Junlin;  Yang, Dan;  Liu, Jieming   |  收藏  |  浏览/下载：20/0  |  提交时间：2024/02/27 Chromosome-level genome assembly of the deep-sea snail Phymorhynchus buccinoides provides insights into the adaptation to the cold seep habitat 期刊论文  OAI收割 BMC GENOMICS, 2023, 卷号: 24, 期号: 1, 页码: 16 作者:  Liu, Zhaoqun;  Huang, Yuting;  Chen, Hao;  Liu, Chang;  Wang, Minxiao   |  收藏  |  浏览/下载：17/0  |  提交时间：2024/04/07 Cold seep  Phymorhynchus buccinoides  Chromosome-level genome  Glutamate regulation  Olfactory/chemosensory  H2S detoxification   Selective activator of human ClpP triggers cell cycle arrest to inhibit lung squamous cell carcinoma 期刊论文  OAI收割 NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 7069 作者:  Zhou, Lin-Lin;  Zhang, Tao;  Xue, Yun;  Yue, Chuan;  Pan, Yihui   |  收藏  |  浏览/下载：3/0  |  提交时间：2024/03/27 Discovery of a highly potent NPAS3 heterodimer inhibitor by covalently modifying ARNT 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2023, 卷号: 139, 页码: 10 作者:  Li, Peizhuo;  Tian, Yucheng;  Shang, Qinghong;  Tang, Cailing;  Hou, Zeng   |  收藏  |  浏览/下载：21/0  |  提交时间：2023/10/17 NPAS3  Covalent inhibitor  Protein -protein interaction  5-nitrothiazole warhead   LINC00955 suppresses colorectal cancer growth by acting as a molecular scaffold of TRIM25 and Sp1 to Inhibit DNMT3B-mediated methylation of the PHIP promoter 期刊论文  OAI收割 BMC CANCER, 2023, 卷号: 23, 期号: 1, 页码: 20 作者:  Ren, Ganglin;  Li, Hongyan;  Hong, Dan;  Hu, Fangyu;  Jin, Rongjia   |  收藏  |  浏览/下载：6/0  |  提交时间：2023/12/08 LINC00955  Colorectal cancer  Cell cycle  CDK2  PHIP  Sp1   A first genome survey sequencing of alvinocaridid shrimp Shinkaicaris leurokolos in deep-sea hydrothermal vent environment 期刊论文  OAI收割 JOURNAL OF THE MARINE BIOLOGICAL ASSOCIATION OF THE UNITED KINGDOM, 2023, 卷号: 103, 页码: 8 作者:  Wang, Aiyang;  Cheng, Jiao;  Xin, Qian;  Sha, Zhongli;  Hui, Min   |  收藏  |  浏览/下载：6/0  |  提交时间：2023/12/13 genome survey  hydrothermal vent  microsatellite DNA  mitogenome  Shinkaicaris leurokolos   Otilonium Bromide acts as a selective USP28 inhibitor and exhibits cytotoxic activity against multiple human cancer cell lines 期刊论文  OAI收割 BIOCHEMICAL PHARMACOLOGY, 2023, 卷号: 215, 页码: 14 作者:  Xu, Zhuo;  Wang, Hui;  Meng, Qian;  Ding, Yiluan;  Zhu, Mengying   |  收藏  |  浏览/下载：11/0  |  提交时间：2023/10/17 Otilonium Bromide  Deubiquitinase  USP28  Selective inhibitor   Spectral and biodistributional engineering of deep near-infrared chromophore 期刊论文  OAI收割 CHINESE CHEMICAL LETTERS, 2023, 卷号: 34, 期号: 9, 页码: 7 作者:  Dong, Yan;  Lu, Xicun;  Li, Yi;  Chen, Weichao;  Yin, Lei   |  收藏  |  浏览/下载：22/0  |  提交时间：2023/10/17 Near infrared fluorophore  In vivo imaging  Molecular engineering  Biological distribution  Angiography