中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [787]
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OAI收割 [787]
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期刊论文 [775]
学位论文 [8]
会议论文 [4]
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2024 [11]
2023 [46]
2022 [62]
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2020 [41]
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Pharmacol... [16]
Chemistry [13]
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共787条,第1-10条
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Rational design and discovery of novel oxalate-like derivatives as aphid-repellent candidates based on odorant-binding protein 3
期刊论文
OAI收割
JOURNAL OF MOLECULAR STRUCTURE, 2024, 卷号: 1301, 页码: 11
作者:
Zhu, Ziwei
;
Li, Jianing
;
Liu, Chong
;
Li, Huilin
;
Lu, Xingxing
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/04/09
Odorant-binding protein
Oxalate-like derivatives
Rational design
Repellent activity
Behavioural control agents
Probing the dynamic thermodynamic resolution and biological activity of Cu(II) and Pd(II) complexes with Schiff base ligand derived from proline
期刊论文
OAI收割
CHINESE CHEMICAL LETTERS, 2024, 卷号: 35, 期号: 4, 页码: 7
作者:
Yu, Tao
;
Soloshonok, Vadim A.
;
Xiao, Zhekai
;
Liu, Hong
;
Wang, Jiang
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/04/09
Schiff bases
Biological activity
Tailor-made amino acids
Asymmetric synthesis
Chiral tridentate ligands
Square-planar Cu(II)-complexes
Square-planar Pd(II)-complexes
Structure-Activity Relationships of 2-(Arylthio)benzoic Acid FTO Inhibitors
期刊论文
OAI收割
ISRAEL JOURNAL OF CHEMISTRY, 2024, 页码: 13
作者:
Yan, Chao
;
Zhang, Qian
;
Xiao, Pan
;
Xie, Xinyun
;
Li, Ming
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2024/03/25
RNA modification
m(6)A
FTO
anticancer
Novel imidazo[1,2,4] triazole derivatives: Synthesis, fluorescence, bioactivity for SHP1
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 265, 页码: 15
作者:
Yan, Xue
;
Zhang, Chun
;
Gao, Li-Xin
;
Liu, Min -Min
;
Yang, Yu-Ting
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/02/27
Imidazo[124] triazole derivatives
Fluorescence property
SHP1
Bioactivity
Cellular imaging
New chromone derivatives bearing thiazolidine-2,4-dione moiety as potent PTP1B inhibitors: Synthesis and biological activity evaluation
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 143, 页码: 9
作者:
Zheng, Yingying
;
Lu, Li
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/01/26
Chromone
Thiazolidine-2
4-dione
Protein tyrosine phosphatase 1B
Inhibitors
Design, synthesis and biological evaluation of betulinic acid derivatives as potential inhibitors of 3CL-protease of SARS-CoV-2
期刊论文
OAI收割
STEROIDS, 2024, 卷号: 202, 页码: 8
作者:
Liu, Yaowen
;
Nie, Tianqing
;
Hou, Jinjun
;
Long, Huali
;
Zhang, Zijia
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2024/03/13
3CLpro
SARS-CoV-2
Betulinic acid
Natural product
Inhibitory activity
Koilodenoids A-G, immunosuppressive spiro dimers of diterpenoids from
Koilodepas hainanense
: structural elucidation and biomimetic transformation
期刊论文
OAI收割
ORGANIC CHEMISTRY FRONTIERS, 2024, 页码: 8
作者:
Ren, Yu
;
Zheng, Cheng-Yu
;
Yao, Jia-Ying
;
He, Shi-Jun
;
Fan, Yao-Yue
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/03/06
Synthesis and Biological Evaluation of β-Lactam Derivatives Targeting Speckle-Type POZ Protein (SPOP)
期刊论文
OAI收割
ACS MEDICINAL CHEMISTRY LETTERS, 2024, 卷号: 15, 期号: 2, 页码: 270-279
作者:
Zhou, Chenmao
;
Hao, Xinyue
;
Chen, Zhengyang
;
Zhang, Runze
;
Zhou, Qian
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2024/03/13
Speckle-type POZ protein (SPOP)
SPOP inhibitors
Clear cell renal cell carcinoma (ccRCC)
Structure-activityrelationship (SAR)
Design, Synthesis, and Biological Evaluation of Potent and Selective PROTAC Degraders of Oncogenic KRAS
G12D
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 2, 页码: 1147-1167
作者:
Zhou, Chuan
;
Fan, Zisheng
;
Gu, Yuejiao
;
Ge, Zhiming
;
Tao, Zhaofan
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/02/27
Discovery and optimization of thieno[3,2-d]pyrimidine derivatives as highly selective inhibitors of cyclin-dependent kinase 7
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 263, 页码: 21
作者:
Zhang, Hongjin
;
Lin, Guohao
;
Jia, Suyun
;
Zhang, Ying
;
Wu, Jianbo
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/01/26
Thieno[3
d ]pyrimidine derivative
Cyclin-dependent kinase 7
Small molecule inhibitor
Kinome selectivity
Triple negative breast cancer