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Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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大连化学物理研究... [136]
上海药物研究所 [79]
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期刊论文 [542]
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Design, synthesis and biological evaluation of chalcone derivatives as potent and orally active hCYP3A4 inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2023, 卷号: 95, 页码: 9
作者:
Lu, Shiwei
;
Zhang, Feng
;
Gong, Jiahao
;
Huang, Jian
;
Zhu, Guanghao
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/12/08
Cytochrome P450 3A4 (CYP3A4)
Inhibitors
Isoquinoline chalcones
Orally active
Asymmetric C1 Extension of Aldehydes through Biocatalytic Cascades for Stereodivergent Synthesis of Mandelic Acids
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2023, 卷号: 62, 期号: 20
作者:
Liu, Yanqiong
;
Fu, Zunyun
;
Dong, Haihong
;
Zhang, Jingxuan
;
Mao, Yingle
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2024/03/27
Asymmetric C-1 Extension
Biocatalysis
Biocatalytic Cascades
(S)-4-Hydroxymandelate Synthase
Mandelic Acids
Using alkali-activated dredge sludge ash-bentonite for low permeability cutoff walls: The engineering properties and micromechanism
期刊论文
OAI收割
ENVIRONMENTAL TECHNOLOGY & INNOVATION, 2023, 卷号: 30, 期号: -, 页码: -
作者:
Hui, Xinminnan
;
Wan, Yong
;
He, Xingxing
;
Li, Jiang-shan
;
Huang, Xiao
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2023/08/02
Dredged sludge ash
Alkali-activated
Vertical barrier
Micomechanism
De-hydroxylation
Sustainability
Allylic hydroxylation of enones useful for the functionalization of relevant drugs and natural products
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 9
作者:
Zheng, Cheng-Yu
;
Yue, Jian-Min
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2023/10/17
Rhodium(III)-Catalyzed C-H/O2 Dual Activation and Macrocyclization: Synthesis and Evaluation of Pyrido[2,1-a]isoindole Grafted Macrocyclic Inhibitors for Influenza H1N1
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2023, 卷号: 62, 期号: 15
作者:
Song, Bichao
;
Guo, Xueying
;
Yang, Li
;
Yu, Haiyue
;
Zong, Xinlei
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/03/27
C-H Activation
Macrocyclization
Multicomponent Coupling
O-2 Activation
Rh Catalysis
Improved 2α-Hydroxylation Efficiency of Steroids by CYP154C2 Using Structure-Guided Rational Design
期刊论文
OAI收割
APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2023, 卷号: 89, 期号: 3
作者:
Gao, Qilin
;
Ma, Bingbing
;
Wang, Qianwen
;
Zhang, Hao
;
Fushinobu, Shinya
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2024/03/27
P450
testosterone
androstenedione
crystal structure
rational design
A turn-on fluorescence assay of tyrosinase activity based on an enzyme-triggered hydroxylation of phenol for conformation of silicon nanoparticles
期刊论文
OAI收割
Sensors and Actuators: B. Chemical, 2023, 期号: 381, 页码: 133478
作者:
Yang JL(杨军丽)
;
Stanislas Nsanzamahoro
;
Wang WF(王伟峰)
;
Zhang Y(张瑛)
;
Wang CB(王铖博)
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2023/10/18
Pharmacokinetics,mass balance,and metabolism of 14C TPN171,a novel PDE5 inhibitor,in humans for the treatment of pulmonary arterial hypertension
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 卷号: 44, 期号: 1, 页码: 221
作者:
He Yifei
;
Liu Yin
;
Yu Jinghua
;
Cheng Huan
;
Odilov Abdullajon
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2023/05/22
TPN171
14CTPN171
PDE5 inhibitor
pulmonary arterial hypertension
healthy volunteers
pharmacokinetics
metabolite identification
mass balance
Insight into the degradation mechanism of fluorene by ferrous/humic acid activated persulfate: Free radical reactions, functional group verification and degradation pathway
期刊论文
OAI收割
FRONTIERS IN ENVIRONMENTAL SCIENCE, 2022, 卷号: 10, 页码: 10
作者:
Li, Haonan
;
Liao, Xiaoyong
;
Li, You
;
Liu, Qiongzhi
;
Luo, Junpeng
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2023/01/13
humic acid (HA)
persulfate activation
fluorene
free radicals
degradation mechanism
Insight into the degradation mechanism of fluorene by ferrous/humic acid activated persulfate: Free radical reactions, functional group verification and degradation pathway
期刊论文
OAI收割
FRONTIERS IN ENVIRONMENTAL SCIENCE, 2022, 卷号: 10, 页码: 10
作者:
Li, Haonan
;
Liao, Xiaoyong
;
Li, You
;
Liu, Qiongzhi
;
Luo, Junpeng
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2023/01/13
humic acid (HA)
persulfate activation
fluorene
free radicals
degradation mechanism