中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [35]
采集方式
OAI收割 [35]
内容类型
期刊论文 [35]
发表日期
2017 [35]
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发表日期:2017
专题:上海药物研究所
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Conformation and dynamics of the C-terminal region in human phosphoglycerate mutase 1
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 12, 页码: 1673-1682
作者:
Liu, Shi-en
;
Hu, Jun-chi
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/01/08
phosphoglycerate mutase 1 (PGAM1)
human cancers
metabolic target
C-terminal region
conformational changes
molecular dynamics simulation
Benzo[c][1,2,5] thiadiazole derivatives: A new class of potent Src homology-2 domain containing protein tyrosine phosphatase-2 (SHP2) inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 27, 期号: 23, 页码: 5154-5157
作者:
Wang, Wen-Long
;
Chen, Xiao-Yu
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/01/08
Benzo[c][1,2,5] thiadiazole derivatives
PTP1B
SHP2
Inhibitors
Structure-activity relationships (SAR)
Src-dependent phosphorylation of mu-opioid receptor at Tyr(336) modulates opiate withdrawal
期刊论文
OAI收割
EMBO MOLECULAR MEDICINE, 2017, 卷号: 9, 期号: 11, 页码: 1521-1536
作者:
Zhang, Lei
;
Kibaly, Cherkaouia
;
Wang, Yu-Jun
;
Xu, Chi
;
Song, Kyu Young
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2019/01/08
lentivirus injection
locus coeruleus
naloxone-precipitated opiate withdrawal
opiate addiction
Src-mediated phosphorylation of MOR at Tyr(336)
Combining chemical and genetic approaches to increase drought resistance in plants
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2017, 卷号: 8
作者:
Cao, Min-Jie
;
Zhang, Yu-Lu
;
Liu, Xue
;
Huang, Huan
;
Zhou, X. Edward
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2019/01/08
Progress of Organic Reactions Catalyzed by N-Heterocyclic Carbenes
期刊论文
OAI收割
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2017, 卷号: 37, 期号: 10, 页码: 2590-2608
作者:
Wang Ao
;
Xiao Yonglong
;
Zhou Yu
;
Xu Jinyi
;
Liu Hong
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2019/01/08
N-heterocyclic carbene
organic catalytic
umpolung
Discovery of cycloalkyl-fused N-thiazol-2-yl-benzamides as tissue non-specific glucokinase activators: Design, synthesis, and biological evaluation
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 139, 页码: 128-152
作者:
Wang, Zhengyu
;
Shi, Xiaofan
;
Zhang, Huan
;
Yu, Liang
;
Cheng, Yanhua
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2019/01/08
Type 2 diabetes mellitus
Hypoglycemia
Dyslipidemia
Glucokinase activators
N-Thiazol-2-yl-benzamides
NatD promotes lung cancer progression by preventing histone H4 serine phosphorylation to activate Slug expression
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2017, 卷号: 8
作者:
Ju, Junyi
;
Chen, Aiping
;
Deng, Yexuan
;
Liu, Ming
;
Wang, Ying
  |  
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2019/01/08
DCZ3301, a novel cytotoxic agent, inhibits proliferation in diffuse large B-cell lymphoma via the STAT3 pathway
期刊论文
OAI收割
CELL DEATH & DISEASE, 2017, 卷号: 8
作者:
Sun, Xi
;
Li, Bo
;
Xie, Bingqian
;
Xu, Zhijian
;
Chang, Gaomei
  |  
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2019/01/08
Synthesis and biological investigation of tetrahydropyridopyrimidinone derivatives as potential multireceptor atypical antipsychotics
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2017, 卷号: 25, 期号: 17, 页码: 4904-4916
作者:
Xiamuxi, Hainimu
;
Wang, Zhen
;
Li, Jianfeng
;
Wang, Yu
;
Wu, Chunhui
  |  
收藏
  |  
浏览/下载:119/0
  |  
提交时间:2019/01/08
Dopamine
Serotonin
Multireceptor
Atypical antipsychotic
5-HT1A
Heteromers of ae opioid and dopamine D1 receptorsmodulate opioid-induced locomotor sensitization in a dopamine-independent manner
期刊论文
OAI收割
BRITISH JOURNAL OF PHARMACOLOGY, 2017, 卷号: 174, 期号: 17, 页码: 2842-2861
作者:
Tao, Yi-Min
;
Yu, Chuan
;
Wang, Wei-Sheng
;
Hou, Yuan-Yuan
;
Xu, Xue-Jun
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/01/08