中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
首页
机构
成果
学者
登录
注册
登陆
×
验证码:
换一张
忘记密码?
记住我
×
校外用户登录
CAS IR Grid
机构
上海药物研究所 [150]
上海营养与健康研究... [31]
大连化学物理研究所 [18]
海洋研究所 [15]
青岛生物能源与过程... [13]
西北高原生物研究所 [10]
更多
采集方式
OAI收割 [376]
iSwitch采集 [9]
内容类型
期刊论文 [350]
学位论文 [24]
会议论文 [11]
发表日期
2024 [4]
2023 [18]
2022 [29]
2021 [24]
2020 [25]
2019 [24]
更多
学科主题
Biochemis... [10]
物理化学 [9]
Cell Biolo... [7]
Plant Scie... [7]
Endocrinol... [5]
Genetics &... [5]
更多
筛选
浏览/检索结果:
共385条,第1-10条
帮助
条数/页:
5
10
15
20
25
30
35
40
45
50
55
60
65
70
75
80
85
90
95
100
排序方式:
请选择
提交时间升序
提交时间降序
发表日期升序
发表日期降序
题名升序
题名降序
作者升序
作者降序
Discovery of betulinic acid derivatives as gut-restricted TGR5 agonists: Balancing the potency and physicochemical properties
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 144, 页码: 18
作者:
Zhuo, Ning
;
Yun, Ying
;
Zhang, Chenlu
;
Guo, Shimeng
;
Yin, Jianpeng
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/03/25
Type 2 Diabetes
TGR5 agonist
Betulinic acid
Gut-restricted
Gallbladder-filling effects
Kinetophores
DRAK2 suppresses autophagy by phosphorylating ULK1 at Ser
56
to diminish pancreatic β cell function upon overnutrition
期刊论文
OAI收割
SCIENCE TRANSLATIONAL MEDICINE, 2024, 卷号: 16, 期号: 733, 页码: 16
作者:
Lu, Yuting
;
Xu, Junyu
;
Li, Yufeng
;
Wang, Ruoran
;
Dai, Chengqiu
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2024/03/13
Structure-based design of potent FABP4 inhibitors with high selectivity against FABP3
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 264, 页码: 10
作者:
Chen, Guofeng
;
Xie, Hang
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/01/26
Methyl substitution
Selectivity
FABP4 inhibitor
Anti-inflammation
Metabolic stability
Bioorthogonal chemistry mediated cell engineering for advanced cell and cell-derived vesicle therapies: Principles, progresses, and remaining challenges
期刊论文
OAI收割
CHEMICAL ENGINEERING JOURNAL, 2024, 卷号: 480, 页码: 19
作者:
Pan, Chao
;
Jiang, Xiuxian
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/02/27
Bioorthogonal chemistry
Metabolic labelling
Cell therapy
Surface engineering
Cell-derived vesicle
AMPK role in epilepsy: a promising therapeutic target?
期刊论文
OAI收割
JOURNAL OF NEUROLOGY, 2023, 页码: 24
作者:
Qi, Yingbei
;
Zhang, Yong-mei
;
Gao, Ya-nan
;
Chen, Wen-gang
;
Zhou, Ting
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/01/26
AMPK
Epilepsy
Neuron Modulation
Metabolism
Ion Channels
mTOR
MiR-337-3p improves metabolic-associated fatty liver disease through regulation of metabolism
期刊论文
OAI收割
ISCIENCE, 2023, 卷号: 26, 期号: 11, 页码: 18
作者:
Xu, Xiaoding
;
Yu, Chuwei
;
He, Hongxiu
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2024/01/16
Abnormality of mussel in the early developmental stages induced by graphene and triphenyl phosphate:
In
silico
toxicogenomic data-mining,
in
vivo,
and toxicity pathway-oriented approach
期刊论文
OAI收割
AQUATIC TOXICOLOGY, 2023, 卷号: 263, 页码: 11
作者:
Wang, Xiaoqing
;
Li, Fei
;
Meng, Xiangjing
;
Xia, Chunlei
;
Ji, Chenglong
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/11/15
Plastic additives
Graphene-based nanomaterials
Toxicogenomic data mining
Combined hazards
Developmental abnormality
Programmable DNA hydrogel provides suitable microenvironment for enhancing autophagy-based therapies in intervertebral disc degeneration treatment
期刊论文
OAI收割
JOURNAL OF NANOBIOTECHNOLOGY, 2023, 卷号: 21
作者:
Qingxin, Song
;
Kai, Jiang
;
Dandan, Zheng
;
Linyu, Jin
;
Xiuyuan, Chen
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/11/10
Intervertebral disc degeneration
Gene therapy
DNA hydrogel
Autophagy
Extracellular matrix
Natural product P57 induces hypothermia through targeting pyridoxal kinase
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 15
作者:
Wang, Ruina
;
Xiao, Lei
;
Pan, Jianbo
;
Bao, Guangsen
;
Zhu, Yunmei
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2024/02/19
Discovery, structural optimization, and anti-tumor bioactivity evaluations of betulinic acid derivatives as a new type of ROR & gamma; antagonists
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 257, 页码: 15
作者:
Mei, Lianghe
;
Xu, Lansong
;
Wu, Sanan
;
Wang, Yafang
;
Xu, Chao
  |  
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2023/10/17
Betulinic acid
ROR & gamma
Target identification
Rationale structure optimization
Anti-tumor effects
antagonists