中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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  • 上海药物研究所 [11]
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发表日期
  • 2019 [11]
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浏览/检索结果: 共11条，第1-10条 帮助

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Discovery of a Highly Selective and Potent kappa Opioid Receptor Agonist from N-Cyclopropylmethyl-7 alpha-phenyl-6,14-endoethanotetrahydronorthebaines with Reduced Central Nervous System (CNS) Side Effects Navigated by the Message-Address Concept 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 24, 页码: 11054-11070
作者:  Xiao, Li;  Wang, Yujun;  Zhang, Mumei;  Wu, Weiwei;  Kong, Linghui
  |  收藏  |  浏览/下载：80/0  |  提交时间：2020/07/01
A Novel Allosteric Inhibitor of Phosphoglycerate Mutase 1 Suppresses Growth and Metastasis of Non-Small-Cell Lung Cancer 期刊论文  OAI收割
CELL METABOLISM, 2019, 卷号: 30, 期号: 6, 页码: 1107-+
作者:  Huang, Ke;  Liang, Qian;  Zhou, Ye;  Jiang, Lu-lu;  Gu, Wei-ming
  |  收藏  |  浏览/下载：81/0  |  提交时间：2020/07/01
Interplay between the bacterial protein deacetylase CobB and the second messenger c-di-GMP 期刊论文  OAI收割
EMBO JOURNAL, 2019, 页码: 18
作者:  Xu, Zhaowei;  Zhang, Hainan;  Zhang, Xingrun;  Jiang, Hewei;  Liu, Chengxi
  |  收藏  |  浏览/下载：19/0  |  提交时间：2020/07/01
SNORD89 promotes stemness phenotype of ovarian cancer cells by regulating Notch1-c-Myc pathway 期刊论文  OAI收割
JOURNAL OF TRANSLATIONAL MEDICINE, 2019, 卷号: 17, 期号: 1, 页码: 15
作者:  Zhu, Wenjing
  |  收藏  |  浏览/下载：43/0  |  提交时间：2020/07/01
Development of Small-Molecules Targeting Receptor Activator of Nuclear Factor-kappa B Ligand (RANKL)-Receptor Activator of Nuclear Factor-kappa B (RANK) Protein-Protein Interaction by Structure-Based Virtual Screening and Hit Optimization 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 11, 页码: 5370-5381
作者:  Jiang, Min;  Peng, Lei;  Yang, Kai;  Wang, Tianqi;  Yan, Xueming
  |  收藏  |  浏览/下载：17/0  |  提交时间：2020/07/01
The inhibitory mechanism of aurintricarboxylic acid targeting serine/threonine phosphatase Stp1 in Staphylococcus aureus: insights from molecular dynamics simulations 期刊论文  OAI收割
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 6, 页码: 850-858
作者:  Liu, Ting-ting;  Yang, Teng;  Gao, Mei-na;  Chen, Kai-xian;  Yang, Song
  |  收藏  |  浏览/下载：9/0  |  提交时间：2020/07/01
The dynamic conformational landscape of the protein methyltransferase SETD8 期刊论文  OAI收割
ELIFE, 2019, 卷号: 8, 页码: 76
作者:  Chen, Shi;  Wiewiora, Rafal P.;  Meng, Fanwang;  Babault, Nicolas;  Ma, Anqi
  |  收藏  |  浏览/下载：16/0  |  提交时间：2020/07/01
Application of multiple chemical and biological approaches for quality assessment of Carthamus tinctorius L. (safflower) by determining both the primary and secondary metabolites 期刊论文  OAI收割
PHYTOMEDICINE, 2019, 卷号: 58, 页码: 12
作者:  Lu, Jia-Xi;  Zhanga, Chun-Xia;  Hu, Ying;  Zhang, Meng-Han;  Wang, Ya-Nan
  |  收藏  |  浏览/下载：13/0  |  提交时间：2020/07/01
Small-Molecule Targeting of Oncogenic FTO Demethylase in Acute Myeloid Leukemia 期刊论文  OAI收割
CANCER CELL, 2019, 卷号: 35, 期号: 4, 页码: 677-+
作者:  Huang, Yue;  Su, Rui;  Sheng, Yue;  Dong, Lei;  Dong, Ze
  |  收藏  |  浏览/下载：18/0  |  提交时间：2020/07/01
Proteomics identifies new therapeutic targets of early-stage hepatocellular carcinoma 期刊论文  OAI收割
NATURE, 2019, 卷号: 567, 期号: 7747, 页码: 257-+
作者:  Jiang, Ying;  Sun, Aihua;  Zhao, Yang;  Ying, Wantao;  Sun, Huichuan
  |  收藏  |  浏览/下载：62/0  |  提交时间：2020/07/01