中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [22]
采集方式
OAI收割 [22]
内容类型
期刊论文 [22]
发表日期
2019 [22]
学科主题
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专题:上海药物研究所
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发表日期:2019
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Discovery of a Highly Selective and Potent kappa Opioid Receptor Agonist from N-Cyclopropylmethyl-7 alpha-phenyl-6,14-endoethanotetrahydronorthebaines with Reduced Central Nervous System (CNS) Side Effects Navigated by the Message-Address Concept
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 24, 页码: 11054-11070
作者:
Xiao, Li
;
Wang, Yujun
;
Zhang, Mumei
;
Wu, Weiwei
;
Kong, Linghui
  |  
收藏
  |  
浏览/下载:80/0
  |  
提交时间:2020/07/01
Pao Pereira Extract Attenuates Testosterone-Induced Benign Prostatic Hyperplasia in Rats by inhibiting 5 alpha-Reductase
期刊论文
OAI收割
SCIENTIFIC REPORTS, 2019, 卷号: 9, 页码: 10
作者:
Liu, Jiakuan
;
Fang, Tian
;
Li, Meiqian
;
Song, Yuting
;
Li, Junzun
  |  
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2020/07/01
Structural Basis of Activation and Sustained Signaling by the PTH Receptor
期刊论文
OAI收割
JOURNAL OF BONE AND MINERAL RESEARCH, 2019, 卷号: 34, 页码: 9-9
作者:
Sutkeviciute, Ieva
;
Clark, Lisa J.
;
Vilardaga, Jean-Pierre
;
Gardella, Thomas J.
;
Wang, Ming-Wei
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2020/07/01
Synthesis of Aryl Propionamide Scaffold Containing a Pentafluorosulfanyl Moiety as SARMs
期刊论文
OAI收割
MOLECULES, 2019, 卷号: 24, 期号: 23, 页码: 13
作者:
Shao, Pingxuan
;
Zhou, Yan
;
Yang, Dehua
;
Wang, Ming-Wei
;
Lu, Wei
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2020/07/01
pentafluorosulfanyl
aryl propionamide
androgen receptor
agonist
SARMs
Interplay between Alzheimer's disease and global glucose metabolism revealed by the metabolic profile alterations of pancreatic tissue and serum in APP/PS1 transgenic mice
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 10, 页码: 1259-1268
作者:
Liu, Xia
;
Wang, Wei
;
Chen, Hua-li
;
Zhang, Hai-yan
;
Zhang, Nai-xia
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2020/07/01
Alzheimer's disease
type 2 diabetes
APP/PS1 transgenic mice
metabolomics
NMR
glucose metabolism dysfunctions
Intravenous formulation of Panax notoginseng root extract: human pharmacokinetics of ginsenosides and potential for perpetrating drug interactions
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 10, 页码: 1351-1363
作者:
Pintusophon, Salisa
;
Niu, Wei
;
Duan, Xiao-na
;
Olaleye, Olajide E.
;
Huang, Yu-hong
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2020/07/01
ginsenoside
cytochrome P450 3A
organic anion-transporting polypeptide 1B3
herbal medicine-drug interactions
XueShuanTong
Panax notoginseng
Rhodium-Catalyzed Enantioselective Addition of Arylboroxines to Isatin-Derived N-Boc Ketimines Using Chiral Phosphite-Olefin Ligands: Asymmetric Synthesis of 3-Aryl-3-amino-2-oxindoles
期刊论文
OAI收割
ORGANIC LETTERS, 2019, 卷号: 21, 期号: 18, 页码: 7493-7497
作者:
Yu, Yue-Na
;
Qi, Wei-Yi
;
Wu, Chun-Yan
;
Xu, Ming-Hua
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2020/07/01
Small molecule IVQ, as a prodrug of gluconeogenesis inhibitor QVO, efficiently ameliorates glucose homeostasis in type 2 diabetic mice
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 9, 页码: 1193-1204
作者:
Zhou, Ting-ting
;
Zhao, Tong
;
Ma, Fei
;
Zhang, Yi-nan
;
Jiang, Jing
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2020/07/01
type 2 diabetes mellitus
hepatic gluconeogenesis
AMPK signaling pathway
(E)-3-(2-(quinoline-4-yl)vinyl)-1H-indol-6-ol (QVO)
4-[2-(1H-indol-3-yl)vinyl]quinoline (IVQ)
prodrug
Orthogonal assays for the identification of inhibitors of the single-stranded nucleic acid binding protein YB-1
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2019, 卷号: 9, 期号: 5, 页码: 997-1007
作者:
Trevarton, Alexander J.
;
Zhou, Yan
;
Yang, Dehua
;
Rewcastle, Gordon W.
;
Flanagan, Jack U.
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2020/07/01
Cancer
YB-1
Luciferase
AlphaScreen
Transcription factor
Single-stranded DNA
Interplay between the bacterial protein deacetylase CobB and the second messenger c-di-GMP
期刊论文
OAI收割
EMBO JOURNAL, 2019, 页码: 18
作者:
Xu, Zhaowei
;
Zhang, Hainan
;
Zhang, Xingrun
;
Jiang, Hewei
;
Liu, Chengxi
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/07/01
c-di-GMP
CobB
diguanylate cyclase
negative feedback loop
protein acetylation