机构

• 上海药物研究所 [554]

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• OAI收割 [554]

内容类型

• 期刊论文 [547]
• 会议论文 [7]

发表日期

• 2024 [10]
• 2023 [51]
• 2022 [49]
• 2021 [41]
• 2020 [42]
• 2019 [28]
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学科主题

• Pharmacol... [12]
• Chemistry [9]
• Biochemist... [4]
• Biophysics [2]
• Cell Biolo... [2]
• Crystallog... [2]
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浏览/检索结果: 共554条，第1-10条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Machine learning prediction for constructing a universal multidimensional information library of Panax saponins (ginsenosides) 期刊论文  OAI收割 FOOD CHEMISTRY, 2024, 卷号: 439, 页码: 10 作者:  Wang, Hongda;  Zhang, Lin;  Li, Xiaohang;  Sun, Mengxiao;  Jiang, Meiting   |  收藏  |  浏览/下载：10/0  |  提交时间：2024/02/19 Retention time  Collision cross section  Machine learning  Multidimensional information library  Hierarchical design   Molecular features of the ligand-free GLP-1R, GCGR and GIPR in complex with Gs proteins 期刊论文  OAI收割 CELL DISCOVERY, 2024, 卷号: 10, 期号: 1, 页码: 13 作者:  Cong, Zhaotong;  Zhao, Fenghui;  Li, Yang;  Luo, Gan;  Mai, Yiting   |  收藏  |  浏览/下载：22/0  |  提交时间：2024/03/13 Discovery of a potent and selective covalent threonine tyrosine kinase (TTK) inhibitor 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2024, 卷号: 143, 页码: 16 作者:  Sun, Yaoliang;  Chen, Zhiwen;  Liu, Guobin;  Chen, Xiaoai;  Shi, Zihan   |  收藏  |  浏览/下载：10/0  |  提交时间：2024/03/25 Inhibitor  Cancer  Threonine tyrosine kinase (TTK)  Covalent   Diastereomers of Steroidal Alkaloids with Cytotoxic Activities against Non-Small-Cell Lung Cancer from the Bulbs of Fritillaria sinica 期刊论文  OAI收割 JOURNAL OF NATURAL PRODUCTS, 2024, 卷号: 87, 期号: 2, 页码: 252-265 作者:  Li, Jia-yuan;  Wu, Shi-fei;  An, Ya-ling;  Yao, Chang-liang;  Yao, Shuai   |  收藏  |  浏览/下载：101/0  |  提交时间：2024/03/13 A novel pterostilbene compound DCZ0825 induces macrophage M1 differentiation and Th1 polarization to exert anti-myeloma and immunomodulatory 期刊论文  OAI收割 INTERNATIONAL IMMUNOPHARMACOLOGY, 2024, 卷号: 127, 页码: 14 作者:  Zhang, Hui;  Hu, Ke;  Lu, Yumeng;  Xu, Zhijian;  Chen, Gege   |  收藏  |  浏览/下载：10/0  |  提交时间：2024/03/25 Multiple myeloma  M1 macrophages  Th1 cells  Immunomodulatory   Benzothiozinone derivatives with anti-tubercular Activity-Further side chain investigation 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 264, 页码: 11 作者:  Wu, Xiaomei;  Wang, Wenxin;  Stelitano, Giovanni;  Riabova, Olga;  Wang, Bin   |  收藏  |  浏览/下载：8/0  |  提交时间：2024/01/26 Anti -tubercular activity  DprE1 inhibitor  Benzothiazinone derivatives  Structure activity relationship   Design and synthesis of cantharidin derivative DCZ5418 as a TRIP13 inhibitor with anti-multiple myeloma activity in vitro and in vivo 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2024, 卷号: 98, 页码: 7 作者:  Dong, Sanfeng;  Hu, Ke;  Shi, Yulong;  Wang, Guanli;  Yu, Dandan   |  收藏  |  浏览/下载：11/0  |  提交时间：2024/02/19 Multiple myeloma  TRIP13 inhibitor  Cantharidin  DCZ5418  DCZ0415   D3Rings: A Fast and Accurate Method for Ring System Identification and Deep Generation of Drug-Like Cyclic Compounds 期刊论文  OAI收割 JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2024, 卷号: 64, 期号: 3, 页码: 724-736 作者:  Ma, Minfei;  Zhang, Xinben;  Zhou, Liping;  Han, Zijian;  Shi, Yulong   |  收藏  |  浏览/下载：19/0  |  提交时间：2024/03/13 Reversible SAHH inhibitor ameliorates MIA-induced osteoarthritis of rats through suppressing MEK/ERK pathway 期刊论文  OAI收割 BIOMEDICINE & PHARMACOTHERAPY, 2024, 卷号: 170, 页码: 6 作者:  Fan, Shu-Hui;  Chang, Yuan;  Xiong, Xiao-Yu;  Xiang, Mai;  Yuan, Wen-Long   |  收藏  |  浏览/下载：9/0  |  提交时间：2024/02/27 DZ2002  Osteoarthritis  Osteoclast  Bone resorption   Structure-based development of potent and selective type-II kinase inhibitors of RIPK1 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 1, 页码: 319-334 作者:  Qin, Ying;  Li, Dekang;  Qi, Chunting;  Xiang, Huaijiang;  Meng, Huyan   |  收藏  |  浏览/下载：6/0  |  提交时间：2024/03/06 RIPK1  Necroptosis  Type-II kinase inhibitors  Rational design  Lead optimization  Structure-activity relationship  Anti-inflammation  Preclinical drug discovery