机构

• 上海药物研究所 [929]

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• OAI收割 [929]

内容类型

• 期刊论文 [905]
• 会议论文 [21]
• 专利 [3]

发表日期

• 2024 [5]
• 2023 [56]
• 2022 [66]
• 2021 [66]
• 2020 [71]
• 2019 [50]
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学科主题

• Biochemist... [6]
• Pharmacolo... [4]
• Chemistry [3]
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• Endocrinol... [1]
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浏览/检索结果: 共929条，第1-10条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Ent-labdane-type diterpene glycosides obtained from Rubus chingii Hu and their inhibitory effects on PDE5A activity 期刊论文  OAI收割 FITOTERAPIA, 2024, 卷号: 173, 页码: 14 作者:  Yu, Jun-dong;  Wang, Jing-Yi;  Liu, Jia-yuan;  Xu, Ye-chun;  Zhang, Xue   |  收藏  |  浏览/下载：9/0  |  提交时间：2024/02/27 diterpene glycosides  Rubus Chingii Hu  PDE5A inhibitory activity  ent-labdane   7-Dehydrocholesterol dictates ferroptosis sensitivity 期刊论文  OAI收割 NATURE, 2024, 卷号: 626, 期号: 7998, 页码: 29 作者:  Li, Yaxu;  Ran, Qiao;  Duan, Qiuhui;  Jin, Jiali;  Wang, Yanjin   |  收藏  |  浏览/下载：13/0  |  提交时间：2024/04/09 Nanobodies as negative allosteric modulators for human calcium sensing receptor 期刊论文  OAI收割 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2024, 卷号: 695, 页码: 9 作者:  Cui, Qianqian;  Wang, Lu;  Wang, Haonan;  Chen, Xiaochen;  Han, Li   |  收藏  |  浏览/下载：16/0  |  提交时间：2024/04/09 G-protein-coupled receptor  Extracellular calcium sensing receptor  Nanobody  Cryo-electron microscope  Systemic Ca 2+homoeostasis   New chromone derivatives bearing thiazolidine-2,4-dione moiety as potent PTP1B inhibitors: Synthesis and biological activity evaluation 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2024, 卷号: 143, 页码: 9 作者:  Zheng, Yingying;  Lu, Li;  Li, Mengyue;  Xu, Dehua;  Zhang, Laishun   |  收藏  |  浏览/下载：8/0  |  提交时间：2024/01/26 Chromone  Thiazolidine-2  4-dione  Protein tyrosine phosphatase 1B  Inhibitors   Discovery, Optimization, and Evaluation of Novel Pyridin-2(1H)-one Analogues as Potent TRK Inhibitors for Cancer Treatment 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 2, 页码: 1168-1183 作者:  Xu, Zichao;  Peng, Xia;  Zhang, Renjie;  Ji, Yinchun;  You, Mengke   |  收藏  |  浏览/下载：10/0  |  提交时间：2024/02/27 Recognition of methamphetamine and other amines by trace amine receptor TAAR1 期刊论文  OAI收割 NATURE, 2023, 卷号: 624, 期号: 7992, 页码: 663-+ 作者:  Liu, Heng;  Zheng, You;  Wang, Yue;  Wang, Yumeng;  He, Xinheng   |  收藏  |  浏览/下载：17/0  |  提交时间：2024/03/25 Safety, tolerability and pharmacokinetics of forsythin in healthy subjects: a double-blinded, placebo-controlled single-dose and multiple-dose escalation and food effect study 期刊论文  OAI收割 ANNALS OF MEDICINE, 2023, 卷号: 55, 期号: 2, 页码: 9 作者:  Li, Cuiyun   |  收藏  |  浏览/下载：22/0  |  提交时间：2024/01/16 Forsythin  pharmacokinetics  safety  tolerability  food effect   Substrate- and Catalyst-Controlled C-H Bond Activation/Annulation for Construction of Pyrido[2,3,4-de]quinazolinones and Indolo[1,2-c]quinazolinones 期刊论文  OAI收割 ADVANCED SYNTHESIS & CATALYSIS, 2023, 页码: 8 作者:  Hou, Xinjiao;  Wang, Run;  Zhou, Jianhui;  Li, Yuan;  Li, Jiyuan   |  收藏  |  浏览/下载：7/0  |  提交时间：2024/01/16 C-H bond activation  Fused heterocycles  Rh(III) catalysis  Ru(II) catalysis   A first-in-human phase 1 study of simnotrelvir, a 3CL-like protease inhibitor for treatment of COVID-19, in healthy adult subjects 期刊论文  OAI收割 EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2023, 卷号: 191, 页码: 9 作者:  Yang, Xin-Mei;  Yang, Yang;  Yao, Bu-Fan;  Ye, Pan-Pan;  Xu, Yan   |  收藏  |  浏览/下载：11/0  |  提交时间：2023/12/11 COVID-19  Simnotrelvir  Safety  Pharmacokinetics  Healthy subjects   Structure-based drug discovery of novel fused- pyrazolone carboxamide derivatives as potent and selective AXL inhibitors 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 12, 页码: 4918-4933 作者:  Fang, Feifei;  Dai, Yang;  Wang, Hao;  Ji, Yinchun;  Liang, Xuewu   |  收藏  |  浏览/下载：7/0  |  提交时间：2024/01/26 derivatives  Antitumor drug development  Potential AXL inhibitor  Antitumor activity  Structure-based drug design  Fused-pyrazolone carboxamide