机构

• 上海药物研究所 [72]

采集方式

• OAI收割 [72]

内容类型

• 期刊论文 [72]

发表日期

• 2023 [4]
• 2022 [3]
• 2021 [5]
• 2019 [2]
• 2018 [3]
• 2017 [3]
• 更多

学科主题

筛选

浏览/检索结果: 共72条，第1-10条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 A first-in-human phase 1 study of simnotrelvir, a 3CL-like protease inhibitor for treatment of COVID-19, in healthy adult subjects 期刊论文  OAI收割 EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2023, 卷号: 191, 页码: 9 作者:  Yang, Xin-Mei;  Yang, Yang;  Yao, Bu-Fan;  Ye, Pan-Pan;  Xu, Yan   |  收藏  |  浏览/下载：11/0  |  提交时间：2023/12/11 COVID-19  Simnotrelvir  Safety  Pharmacokinetics  Healthy subjects   Design, synthesis and biological evaluation of peptidomimetic benzothiazolyl ketones as 3CLpro inhibitors against SARS-CoV-2 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 257, 页码: 13 作者:  Yang, Hanxi;  You, Mengyuan;  Shu, Xiaoyang;  Zhen, Jingyao;  Zhu, Mengwei   |  收藏  |  浏览/下载：13/0  |  提交时间：2023/10/17 Peptidomimetics  Benzothiazolyl ketone  3CLpro inhibitor  Pharmacokinetic properties  SARS-CoV-2   Efficacy and safety of SIM0417 (SSD8432) plus ritonavir for COVID-19 treatment: a randomised, double-blind, placebo- controlled, phase 1b trial 期刊论文  OAI收割 LANCET REGIONAL HEALTH-WESTERN PACIFIC, 2023, 卷号: 38, 页码: 13 作者:  Wang, Fuxiang;  Xiao, Wen;  Tang, Yimin;  Cao, Mengli;  Shu, Dan   |  收藏  |  浏览/下载：12/0  |  提交时间：2023/10/17 Covid-19  3CL protease inhibitor  SARS-CoV-2 viral load  Alleviation of COVID-19 symptoms   Targeting lactate metabolism and immune interaction in breast tumor via protease-triggered delivery 期刊论文  OAI收割 JOURNAL OF CONTROLLED RELEASE, 2023, 卷号: 358, 页码: 706-717 作者:  Zhao, Pengfei;  Wang, Shuang;  Jiang, Jizong;  Gao, Yanrong;  Wang, Yuewei   |  收藏  |  浏览/下载：12/0  |  提交时间：2023/10/17 Legumain  Lactate  Tumor immune microenvironment (TIME)  Quercetin  Immunometabolism   Targeting UHRF1-SAP30-MXD4 axis for leukemia initiating cell eradication in myeloid leukemia 期刊论文  OAI收割 CELL RESEARCH, 2022, 页码: 19 作者:  Hu, Cheng-Long;  Chen, Bing-Yi;  Li, Zijuan;  Yang, Tianbiao;  Xu, Chun-Hui   |  收藏  |  浏览/下载：30/0  |  提交时间：2022/12/13 SLL-627 Is a Highly Selective and Potent ? Opioid Receptor (KOR) Agonist with an Unexpected Nonreduction in Locomotor Activity 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2022, 页码: 16 作者:  Kong, Linghui;  Shu, Xuelian   |  收藏  |  浏览/下载：42/0  |  提交时间：2022/08/30 SLC1A1-mediated cellular and mitochondrial influx of R-2-hydroxyglutarate in vascular endothelial cells promotes tumor angiogenesis in IDH1-mutant solid tumors 期刊论文  OAI收割 CELL RESEARCH, 2022, 页码: 21 作者:  Wang, Xiaomin;  Chen, Ziqi;  Xu, Jun;  Tang, Shuai;  An, Nan   |  收藏  |  浏览/下载：39/0  |  提交时间：2022/06/15 A proteomic and phosphoproteomic landscape of KRAS mutant cancers identifies combination therapies 期刊论文  OAI收割 MOLECULAR CELL, 2021, 卷号: 81, 期号: 19, 页码: 4076-+ 作者:  Liu, Zhiwei;  Liu, Yingluo;  Qian, Lili;  Jiang, Shangwen;  Gai, Xiameng   |  收藏  |  浏览/下载：60/0  |  提交时间：2021/12/01 Structural mechanism of calcium-mediated hormone recognition and G beta interaction by the human melanocortin-1 receptor 期刊论文  OAI收割 CELL RESEARCH, 2021, 页码: 11 作者:  Ma, Shanshan;  Chen, Yan;  Dai, Antao;  Yin, Wanchao;  Guo, Jia   |  收藏  |  浏览/下载：50/0  |  提交时间：2021/11/04 Preclinical characterization of LOXO-338, a novel, oral and selective BCL2 inhibitor. 期刊论文  OAI收割 CANCER RESEARCH, 2021, 卷号: 81, 期号: 13, 页码: 1 作者:  Brandhuber, Barbara;  Ku, Karin;  Lallena, Maria J.;  Baquero, Carmen;  Choy, Regina   |  收藏  |  浏览/下载：36/0  |  提交时间：2021/11/04