中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [63]
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OAI收割 [63]
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期刊论文 [61]
会议论文 [2]
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2023 [7]
2022 [4]
2021 [6]
2020 [4]
2019 [4]
2018 [7]
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专题:上海药物研究所
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A first-in-human phase 1 study of simnotrelvir, a 3CL-like protease inhibitor for treatment of COVID-19, in healthy adult subjects
期刊论文
OAI收割
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2023, 卷号: 191, 页码: 9
作者:
Yang, Xin-Mei
;
Yang, Yang
;
Yao, Bu-Fan
;
Ye, Pan-Pan
;
Xu, Yan
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/12/11
COVID-19
Simnotrelvir
Safety
Pharmacokinetics
Healthy subjects
Asponchimides A-E: new enantiomeric N-acetyldopamine trimers from Aspongopus chinensis
期刊论文
OAI收割
CHINESE JOURNAL OF NATURAL MEDICINES, 2023, 卷号: 21, 期号: 11, 页码: 859-867
作者:
Nie, Jinchun
;
Mei, Fang
;
Zheng, Yueyuan
;
Wen, Qiuyi
;
Li, Zhenwei
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/01/26
Aspongopus chinensis
N-acetyldopamine trimer
ECD calculations
NO inhibitory activity
Ligand activation mechanisms of human KCNQ2 channel
期刊论文
OAI收割
Nature communications, 2023, 卷号: 14, 期号: 1, 页码: 6632
作者:
Ma, Demin
;
Zheng, Yueming
;
Li, Xiaoxiao
;
Zhou, Xiaoyu
;
Yang, Zhenni
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2024/03/26
A pilot study of the differentiated landscape of peripheral blood mononuclear cells from children with incomplete versus complete Kawasaki disease
期刊论文
OAI收割
WORLD JOURNAL OF PEDIATRICS, 2023, 页码: 12
作者:
Sun, Shu-Na
;
Zhou, Yan
;
Fu, Xing
;
Zheng, Yuan-Zheng
;
Xie, Cao
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2023/10/17
The PIWI-specific insertion module helps load longer piRNAs for translational activation essential for male fertility
期刊论文
OAI收割
SCIENCE CHINA-LIFE SCIENCES, 2023, 页码: 23
作者:
Wang, Xin
;
Lin, Di-Hang
;
Yan, Yue
;
Wang, An-Hui
;
Liao, Jiaoyang
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2023/10/17
PIWI
piRNAs
PIWI-Ins
translational activation
spermatid development
male fertility
A RIPK3-independent role of MLKL in suppressing parthanatos promotes immune evasion in hepatocellular carcinoma
期刊论文
OAI收割
CELL DISCOVERY, 2023, 卷号: 9, 期号: 1, 页码: 15
作者:
Jiang, Xifei
;
Deng, Wenjia
;
Tao, Siyao
;
Tang, Zheng
;
Chen, Yuehong
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2023/04/10
Recombinant cell-penetrating trichosanthin synergizes anti-PD-1 therapy in colorectal tumor
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 2023, 卷号: 19, 期号: 6, 页码: 1698-1712
作者:
Zhang, Meng
;
Liu, Ergang
;
Chen, Guihua
;
Tang, Yisi
;
Fang, Yuefei
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2023/10/17
Trichosanthin
cell -penetrating peptide
anti -PD-1 therapy
tumor immune microenvironment
colorectal cancer
A substrate-controlled Ru(ii)-catalyzed C-H activation/[5+2] annulation cascade and unusual acyl migration to synthesize diverse indoline scaffolds
期刊论文
OAI收割
ORGANIC CHEMISTRY FRONTIERS, 2022, 页码: 6
作者:
Zheng, Miao
;
Zhou, Jianhui
;
Fang, Feifei
;
Xu, Zichao
;
Zheng, Fuqiang
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2023/04/10
Rh(III)-Catalyzed C-H Activation and [4+1+1] Sequential Cyclization Cascade to Give Highly Fused Indano[1,2-b]azirines
期刊论文
OAI收割
ORGANIC LETTERS, 2022, 页码: 5
作者:
Zheng, Fuqiang
;
Zhou, Jianhui
;
Fang, Feifei
;
Li, Jiyuan
;
Wang, Jing
  |  
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2022/08/30
Transcytosis mechanisms of cell-penetrating peptides: Cation-independent CC12 and cationic penetratin
期刊论文
OAI收割
JOURNAL OF PEPTIDE SCIENCE, 2022, 页码: 9
作者:
Zhu, Minjiao
;
Liu, Haiyang
;
Cao, Wenjiao
;
Fang, Yuefei
;
Chen, Zheng
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2022/06/15
cell-penetrating peptides
direct translocation pathway
drug delivery
endocytic pathway
penetration
transcytosis
cell internalization mechanism