中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [10]
采集方式
OAI收割 [10]
内容类型
期刊论文 [10]
发表日期
2022 [1]
2021 [2]
2020 [1]
2019 [3]
2018 [1]
2010 [1]
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专题:上海药物研究所
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Potentiation of Vancomycin: Creating Cooperative Membrane Lysis through a "Derivatization-for-Sensitization" Approach
期刊论文
OAI收割
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2022, 卷号: 144, 期号: 23, 页码: 10622-10639
作者:
Lei, E.
;
Tao, Huanyu
;
Jiao, Shang
;
Yang, Anming
;
Zhou, Yu
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2022/08/16
Impurity Identification and Scale-Up of a Novel Glycopeptide Antibiotic
期刊论文
OAI收割
ORGANIC PROCESS RESEARCH & DEVELOPMENT, 2021, 卷号: 25, 期号: 11, 页码: 2390-2402
作者:
Jiao, Shang
;
Guan, Dongliang
;
Xu, Lili
;
Liu, Bo
;
Shi, Weiwei
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2022/01/18
glycopeptide antibiotics
impurity
analytical method
process optimization and development
An integrative drug repositioning framework discovered a potential therapeutic agent targeting COVID-19
期刊论文
OAI收割
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2021, 卷号: 6, 期号: 1, 页码: 16
作者:
Ge, Yiyue
;
Tian, Tingzhong
;
Huang, Suling
;
Wan, Fangping
;
Li, Jingxin
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2022/06/15
Biomimetic metal-organic nanoparticles prepared with a 3D-printed microfluidic device as a novel formulation for disulfiram-based therapy against breast cancer
期刊论文
OAI收割
APPLIED MATERIALS TODAY, 2020, 卷号: 18, 页码: 12
作者:
Chang, Ya
;
Jiang, Jizong
;
Chen, Wu
;
Yang, Wen
;
Chen, Lili
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2020/07/01
Biomimetic delivery
Metal-organic nanoparticle
Disulfiram
Copper diethyldithiocarbamate
Microfluidic
Breast cancer
DZ2002 ameliorates fibrosis, inflammation, and vasculopathy in experimental systemic sclerosis models
期刊论文
OAI收割
ARTHRITIS RESEARCH & THERAPY, 2019, 卷号: 21, 期号: 1, 页码: 15
作者:
Zhang, Zongwang
;
Wu, Yanwei
;
Wu, Bing
;
Qi, Qing
;
Li, Heng
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2020/07/01
Systemic sclerosis
SAHH inhibitor
Fibrosis
Inflammation
Vasculopathy
TGF-beta
Interplay between the bacterial protein deacetylase CobB and the second messenger c-di-GMP
期刊论文
OAI收割
EMBO JOURNAL, 2019, 页码: 18
作者:
Xu, Zhaowei
;
Zhang, Hainan
;
Zhang, Xingrun
;
Jiang, Hewei
;
Liu, Chengxi
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2020/07/01
c-di-GMP
CobB
diguanylate cyclase
negative feedback loop
protein acetylation
Discovery of Potent and Noncovalent Reversible EGFR Kinase Inhibitors of EGFR(L858R/T790M/C797S)
期刊论文
OAI收割
ACS MEDICINAL CHEMISTRY LETTERS, 2019, 卷号: 10, 期号: 6, 页码: 869-873
作者:
Li, Qiannan
;
Zhang, Tao
;
Li, Shiliang
;
Tong, Linjiang
;
Li, Junyu
  |  
收藏
  |  
浏览/下载:58/0
  |  
提交时间:2020/07/01
EGFR
mutant
inhibitor
C797S
Design, Synthesis, and Biological Evaluation of Pyrimido[4,5-d]pyrimidine-2,4(1H,3H)-diones as Potent and Selective Epidermal Growth Factor Receptor (EGFR) Inhibitors against L858R/T790M Resistance Mutation
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 61, 期号: 13, 页码: 5609-5622
作者:
Hao, Yongjia
;
Lyu, Jiankun
;
Qu, Rong
;
Tong, Yi
;
Sun, Deheng
  |  
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2019/01/08
Design, Synthesis, and Interaction Study of Quinazoline-2(1H)-thione Derivatives as Novel Potential Bcl-x(L) Inhibitors
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2010, 卷号: 53, 期号: 9, 页码: 3465-3479
作者:
Feng, Yu
;
Ding, Xiao
;
Chen, Tao
;
Chen, Lili
;
Liu, Fang
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/01/08
4-(Phenylsulfonamidomethyl) benzamides as potent and selective inhibitors of the 11 beta-hydroxysteroid dehydrogenase type 1 with efficacy in diabetic ob/ob mice
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2009, 卷号: 19, 期号: 15, 页码: 4455-4458
作者:
Zhang, Xu
;
Zhou, Zhou
;
Yang, Huaiyu
;
Chen, Junhua
;
Feng, Ying
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/01/08
11 beta-HSD1 inhibitors
4-(Phenylsulfonamidomethyl) benzamide
Type 2 diabetes