机构

• 上海药物研究所 [23]

采集方式

• OAI收割 [23]

内容类型

• 期刊论文 [22]
• 会议论文 [1]

发表日期

• 2023 [1]
• 2021 [1]
• 2017 [2]
• 2016 [1]
• 2014 [5]
• 2012 [2]
• 更多

学科主题

筛选

浏览/检索结果: 共23条，第1-10条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 A first-in-human phase 1 study of simnotrelvir, a 3CL-like protease inhibitor for treatment of COVID-19, in healthy adult subjects 期刊论文  OAI收割 EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2023, 卷号: 191, 页码: 9 作者:  Yang, Xin-Mei;  Yang, Yang;  Yao, Bu-Fan;  Ye, Pan-Pan;  Xu, Yan   |  收藏  |  浏览/下载：11/0  |  提交时间：2023/12/11 COVID-19  Simnotrelvir  Safety  Pharmacokinetics  Healthy subjects   Gossypol, a novel modulator of VCP, induces autophagic degradation of mutant huntingtin by promoting the formation of VCP/p97-LC3-mHTT complex 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2021, 卷号: 42, 期号: 10, 页码: 1556-1566 作者:  Li, Xiao-jing;  Zhang, Yuan-yuan;  Fu, Yu-hua;  Zhang, Hao;  Li, He-xuan   |  收藏  |  浏览/下载：12/0  |  提交时间：2024/03/21 Huntington disease  mutant huntingtin protein  gossypol acetate  VCP  LC3  autophagic degradation  drug reposition   Amyloid beta: structure, biology and structure-based therapeutic development 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 9, 页码: 1205-1235 作者:  Chen, Guo-fang;  Xu, Ting-hai;  Yan, Yan;  Zhou, Yu-ren;  Jiang, Yi   |  收藏  |  浏览/下载：29/0  |  提交时间：2019/01/08 amyloid beta peptide  amyloid precursor protein  Alzheimer's disease  neurodegenerative diseases  drug discovery   A small-molecule inhibitor of NF-kappa B-inducing kinase (NIK) protects liver from toxin-induced inflammation, oxidative stress, and injury 期刊论文  OAI收割 FASEB JOURNAL, 2017, 卷号: 31, 期号: 2, 页码: 711-718 作者:  Ren, Xiaomeng;  Li, Xinzhi;  Jia, Linna;  Chen, Deheng;  Hou, Hai   |  收藏  |  浏览/下载：25/0  |  提交时间：2019/01/08 NIK  liver injury  inflammation  CCl4   Advances in development of fluorescent probes for detecting amyloid-beta aggregates 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2016, 卷号: 37, 期号: 6, 页码: 719-730 作者:  Xu, Ming-ming;  Ren, Wen-ming;  Tang, Xi-can;  Hu, You-hong;  Zhang, Hai-yan   |  收藏  |  浏览/下载：15/0  |  提交时间：2019/01/08 Alzheimer's disease  diagnostic biomarker  amyloid-beta  optical imaging  near-infrared fluorescent probes   Synthesis and structure-activity relationship of non-phosphorus-based fructose-1,6-bisphosphatase inhibitors: 2,5-Diphenyl-1,3,4-oxadiazoles 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2014, 卷号: 83, 页码: 15-25 作者:  Liao, Ben-Ren;  He, Hai-Bing;  Yang, Ling-Ling;  Gao, Li-Xin;  Chang, Liang   |  收藏  |  浏览/下载：8/0  |  提交时间：2019/01/08 Diabetes  Antidiabetic  Fructose-1,6-bisphosphatase (FBPase)  Inhibitor  2,5-Diphenyl-1,3,4-oxadiazoles   Synthesis of bufalin derivatives with inhibitory activity against prostate cancer cells 期刊论文  OAI收割 NATURAL PRODUCT RESEARCH, 2014, 卷号: 28, 期号: 11, 页码: 843-847 作者:  Yuan, Xiao-Feng;  Tian, Hai-Yan;  Li, Juan;  Jin, Lu;  Jiang, Shu-Tai   |  收藏  |  浏览/下载：12/0  |  提交时间：2019/01/08 bufalin  prostate cancer  Na+  K+-ATPase  androgen receptor   Chemical constituents from Sarcopyramis nepalensis Wall 期刊论文  OAI收割 PHYTOCHEMISTRY LETTERS, 2014, 卷号: 8, 页码: 101-104 作者:  Wei, Wei-bin;  Huang, Yu-jie;  Cong, Hai-jian;  Zhang, Shu-wei;  Pan, Da-ren   |  收藏  |  浏览/下载：22/0  |  提交时间：2019/01/08 Sarcopyamis nepalensis  Melastomataceae  Megastigmane  Terpenic glycosides   A bufadienolide derived androgen receptor antagonist with inhibitory activities against prostate cancer cells 期刊论文  OAI收割 CHEMICO-BIOLOGICAL INTERACTIONS, 2014, 卷号: 207, 页码: 16-22 作者:  Tian, Hai-Yan;  Yuan, Xiao-Feng;  Jin, Lu;  Li, Juan;  Luo, Cheng   |  收藏  |  浏览/下载：20/0  |  提交时间：2019/01/08 Androgen receptor  Antagonist  Bufadienolide  Molecular docking  Na+/K+ ATPase   Streptospirodienoic acids A and B, 6,6-spiroketal polyketides from Streptomyces sp. 期刊论文  OAI收割 RSC ADVANCES, 2014, 卷号: 4, 期号: 108, 页码: 63324-63327 作者:  Chen, Yan-Ping;  Liu, Qian;  Gao, Hao;  Lin, Hai-Peng;  Tian, Hai-Yan   |  收藏  |  浏览/下载：12/0  |  提交时间：2019/01/08