机构

• 上海药物研究所 [232]

采集方式

• OAI收割 [232]

内容类型

• 期刊论文 [228]
• 会议论文 [4]

发表日期

• 2024 [1]
• 2023 [19]
• 2022 [20]
• 2021 [29]
• 2020 [18]
• 2019 [23]
• 更多

学科主题

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浏览/检索结果: 共232条，第1-10条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 The promise and challenges of combination therapies with antibody-drug conjugates in solid tumors 期刊论文  OAI收割 JOURNAL OF HEMATOLOGY & ONCOLOGY, 2024, 卷号: 17, 期号: 1, 页码: 32 作者:  Wei, Qing;  Li, Peijing;  Yang, Teng;  Zhu, Jiayu;  Sun, Lu   |  收藏  |  浏览/下载：24/0  |  提交时间：2024/02/27 Antibody-drug conjugate  Solid tumor  Combination therapy  Immunotherapy  Targeted therapy   Systematical targeted multicomponent characterization and comparison of Arnebiae Radix and its three confusing species by offline two-dimensional liquid chromatography/LTQ-Orbitrap mass spectrometry 期刊论文  OAI收割 ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2023, 页码: 13 作者:  Sha, Fei;  Zhang, Jianqing;  Yang, Huanya;  Hu, Yunshu;  Wei, Wenlong   |  收藏  |  浏览/下载：12/0  |  提交时间：2024/02/19 Arnebiae Radix  Two-dimensional liquid chromatography  Mass defect filter  Precursor ion list  Components characterization   A first-in-human phase 1 study of simnotrelvir, a 3CL-like protease inhibitor for treatment of COVID-19, in healthy adult subjects 期刊论文  OAI收割 EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2023, 卷号: 191, 页码: 9 作者:  Yang, Xin-Mei;  Yang, Yang;  Yao, Bu-Fan;  Ye, Pan-Pan;  Xu, Yan   |  收藏  |  浏览/下载：11/0  |  提交时间：2023/12/11 COVID-19  Simnotrelvir  Safety  Pharmacokinetics  Healthy subjects   The endocannabinoid N-arachidonoyl dopamine is critical for hyperalgesia induced by chronic sleep disruption 期刊论文  OAI收割 NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 13 作者:  Ding, Weihua;  Yang, Liuyue;  Shi, Eleanor;  Kim, Bowon;  Low, Sarah   |  收藏  |  浏览/下载：24/0  |  提交时间：2024/01/16 Design, synthesis of auristatins-glucuronide conjugates targeting the β-glucuronidase in tumor microenvironment 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2023, 卷号: 95, 页码: 5 作者:  Wang, Yujie;  Xu, Keshi;  Liu, Hongchun;  Zhang, Wei;  Hu, Chun   |  收藏  |  浏览/下载：4/0  |  提交时间：2023/12/19 Auristatin E  beta-Glucuronidase  Antiproliferation  Tumor microenvironment   Natural product P57 induces hypothermia through targeting pyridoxal kinase 期刊论文  OAI收割 NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 15 作者:  Wang, Ruina;  Xiao, Lei;  Pan, Jianbo;  Bao, Guangsen;  Zhu, Yunmei   |  收藏  |  浏览/下载：24/0  |  提交时间：2024/02/19 Degradation of Cyclin-Dependent Kinase 9/Cyclin T1 by Optimized Microtubule-Associated Protein 1 Light Chain 3 Beta-Recruiting Coumarin Analogs 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 17 作者:  Zeng, Yanping;  Xiao, Jian;  Xu, Yuanxin;  Wei, Fan;  Tian, Lina   |  收藏  |  浏览/下载：7/0  |  提交时间：2023/10/17 Hyodeoxycholic acid ameliorates nonalcoholic fatty liver disease by inhibiting RAN-mediated PPARa nucleus-cytoplasm shuttling 期刊论文  OAI收割 NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 18 作者:  Zhong, Jing;  He, Xiaofang;  Gao, Xinxin;  Liu, Qiaohong;  Zhao, Yu   |  收藏  |  浏览/下载：5/0  |  提交时间：2023/12/08 Prime editing-based gene correction alleviates the hyperexcitable phenotype and seizures of a genetic epilepsy mouse model 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2023, 页码: 4 作者:  Cao, Bi-rong;  Huang, Yi-ming;  Tian, Fu-yun;  Li, Jin-hui;  Xu, Chun-long   |  收藏  |  浏览/下载：26/0  |  提交时间：2023/10/17 Unprecedented spirodioxynaphthalenes from the endophytic fungus Phyllosticta ligustricola HDF-L-2 derived from the endangered conifer Pseudotsuga gaussenii 期刊论文  OAI收割 PHYTOCHEMISTRY, 2023, 卷号: 211, 页码: 10 作者:  Chen, Hao-Wei;  Jiang, Chun-Xiao;  Ma, Guang-Lei;  Wu, Xi-Ying;  Jiang, Wei   |  收藏  |  浏览/下载：26/0  |  提交时间：2023/10/17 Phyllosticta ligustricola  Phyllostictaceae  Pseudotsuga gaussenii  Pinaceae  Phyligustricins A-D  Spirodioxynaphthalenes  Antimicrobial effects  Cytotoxicity  ACL/ACC1 inhibitory effects