中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [17]
采集方式
OAI收割 [17]
内容类型
期刊论文 [17]
发表日期
2023 [1]
2021 [2]
2020 [2]
2019 [1]
2016 [1]
2015 [2]
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专题:上海药物研究所
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Structural genomics of the human dopamine receptor system
期刊论文
OAI收割
CELL RESEARCH, 2023, 页码: 13
作者:
Xu, Peiyu
;
Huang, Sijie
;
Krumm, Brian E.
;
Zhuang, Youwen
;
Mao, Chunyou
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2023/10/17
A 36-week multicenter, randomized, double-blind, placebo-controlled, parallel-group, phase 3 clinical trial of sodium oligomannate for mild-to-moderate Alzheimer’s dementia
期刊论文
OAI收割
Alzheimer's Research & Therapy, 2021, 卷号: 13, 期号: 1
作者:
Xiao,Shifu
;
Chan,Piu
;
Wang,Tao
;
Hong,Zhen
;
Wang,Shuzhen
  |  
收藏
  |  
浏览/下载:84/0
  |  
提交时间:2021/05/24
Sodium oligomannate
Efficacy
Safety
Alzheimer’s disease
Clinical trial
Structural insights into the human D1 and D2 dopamine receptor signaling complexes
期刊论文
OAI收割
CELL, 2021, 卷号: 184, 期号: 4, 页码: 931-+
作者:
Zhuang, Youwen
;
Xu, Peiyu
;
Mao, Chunyou
;
Wang, Lei
;
Krumm, Brian
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2021/05/24
Crystallography-guided discovery of carbazole-based retinoic acid-related orphan receptor gamma-t (ROR gamma t) modulators: insights into different protein behaviors with "short" and "long" inverse agonists
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 11
作者:
Yu, Ming-cheng
;
Yang, Feng
;
Ding, Xiao-yu
;
Sun, Nan-nan
;
Jiang, Zheng-yuan
  |  
收藏
  |  
浏览/下载:93/0
  |  
提交时间:2020/12/24
RORγ
t
cocrystal structures
MD simulation
“
short”
inverse agonists
agonists
“
long”
inverse agonists
Identification and characterization of isocitrate dehydrogenase 1 (IDH1) as a functional target of marine natural product grincamycin B
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 13
作者:
Wang, Zheng
;
Li, Zeng-xia
;
Zhao, Wen-cao
;
Huang, Hong-bo
;
Wang, Jia-qi
  |  
收藏
  |  
浏览/下载:54/0
  |  
提交时间:2020/12/24
grincamycin B
marine natural product
isocitrate dehydrogenase 1
apoptosis
ER stress
intracellular ROS
Zebrafish embryos
hematological malignancies
A Novel Allosteric Inhibitor of Phosphoglycerate Mutase 1 Suppresses Growth and Metastasis of Non-Small-Cell Lung Cancer
期刊论文
OAI收割
CELL METABOLISM, 2019, 卷号: 30, 期号: 6, 页码: 1107-+
作者:
Huang, Ke
;
Liang, Qian
;
Zhou, Ye
;
Jiang, Lu-lu
;
Gu, Wei-ming
  |  
收藏
  |  
浏览/下载:81/0
  |  
提交时间:2020/07/01
Small-Molecule Targeting of E3 Ligase Adaptor SPOP in Kidney Cancer
期刊论文
OAI收割
CANCER CELL, 2016, 卷号: 30, 期号: 3, 页码: 474-484
作者:
Guo, Zhong-Qiang
;
Zheng, Tong
;
Chen, Baoen
;
Luo, Cheng
;
Ouyang, Sisheng
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2019/01/08
Design, Synthesis, and Biological Evaluation of Novel Nonsteroidal FarnesoidX Receptor (FXR) Antagonists: Molecular Basis of FXR Antagonism
期刊论文
OAI收割
CHEMMEDCHEM, 2015, 卷号: 10, 期号: 7, 页码: 1184-1199
作者:
Huang, Huang
;
Si, Pei
;
Wang, Lei
;
Xu, Yong
;
Xu, Xin
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/01/08
antagonists
mechanism of action
molecular dynamics
nonsteroidal ligands
receptors
A highly efficient approach to unnatural amino-acids containing 3-hydroxyoxindole skeleton via a one-pot, three-component procedure
期刊论文
OAI收割
TETRAHEDRON LETTERS, 2015, 卷号: 56, 期号: 4, 页码: 586-589
作者:
Huang, Huang
;
Xu, Yong
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/01/08
Unnatural amino-acid
3-Hydroxyoxindole
Multicomponent reaction
Isatin
Benzophenone imine
Transdermal and Biotramsformation Differences between Amindevulinic Acid Hydrochloride Solution and Gel Formula
期刊论文
OAI收割
Chinese Journal of Modern Applied Pharmacy, 2014, 卷号: 31, 期号: 1, 页码: 57-60
作者:
Guo Qianqian
;
Liu Jinhua
;
Liu Ergang
;
Zhao Yongxing
;
Hua Haiying
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/01/08
aminolevulinic acid hydrochloride
transdermal absorption
protoporphyrin