中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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  • 上海药物研究所 [92]
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Proteomics analysis of histone deacetylase inhibitor-resistant solid tumors reveals resistant signatures and potential drug combinations 期刊论文  OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 11
作者:  
Hao, Bing-bing;  Ma, Ke;  Xu, Jun-yu;  Fan, Ru-feng;  Zhao, Wen-si
  |  收藏  |  浏览/下载:13/0  |  提交时间:2024/03/25
Discovery of a potent and selective covalent threonine tyrosine kinase (TTK) inhibitor 期刊论文  OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 143, 页码: 16
作者:  
Sun, Yaoliang;  Chen, Zhiwen;  Liu, Guobin;  Chen, Xiaoai;  Shi, Zihan
  |  收藏  |  浏览/下载:8/0  |  提交时间:2024/03/25
A novel pterostilbene compound DCZ0825 induces macrophage M1 differentiation and Th1 polarization to exert anti-myeloma and immunomodulatory 期刊论文  OAI收割
INTERNATIONAL IMMUNOPHARMACOLOGY, 2024, 卷号: 127, 页码: 14
作者:  
Zhang, Hui;  Hu, Ke;  Lu, Yumeng;  Xu, Zhijian;  Chen, Gege
  |  收藏  |  浏览/下载:9/0  |  提交时间:2024/03/25
Design and synthesis of cantharidin derivative DCZ5418 as a TRIP13 inhibitor with anti-multiple myeloma activity in vitro and in vivo 期刊论文  OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2024, 卷号: 98, 页码: 7
作者:  
Dong, Sanfeng;  Hu, Ke;  Shi, Yulong;  Wang, Guanli;  Yu, Dandan
  |  收藏  |  浏览/下载:10/0  |  提交时间:2024/02/19
Qing-Zhi-Tiao-Gan-Tang (QZTGT) prevents nonalcoholic steatohepatitis (NASH) by expression pattern correction 期刊论文  OAI收割
JOURNAL OF ETHNOPHARMACOLOGY, 2023, 卷号: 317, 页码: 14
作者:  
Chu, Hang;  Zhang, Weitao;  Tan, Yan;  Diao, Zhipeng;  Li, Peng
  |  收藏  |  浏览/下载:22/0  |  提交时间:2023/10/17
A first-in-human phase 1 study of simnotrelvir, a 3CL-like protease inhibitor for treatment of COVID-19, in healthy adult subjects 期刊论文  OAI收割
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2023, 卷号: 191, 页码: 9
作者:  
Yang, Xin-Mei;  Yang, Yang;  Yao, Bu-Fan;  Ye, Pan-Pan;  Xu, Yan
  |  收藏  |  浏览/下载:11/0  |  提交时间:2023/12/11
Berberine derivative DCZ0358 induce oxidative damage by ROS-mediated JNK signaling in DLBCL cells 期刊论文  OAI收割
INTERNATIONAL IMMUNOPHARMACOLOGY, 2023, 卷号: 125, 页码: 15
作者:  
Feng, Qilin;  Hu, Ke;  Hu, Huifang;  Lu, Yumeng;  Zhang, Hui
  |  收藏  |  浏览/下载:24/0  |  提交时间:2024/01/16
Dihydrocelastrol induces antitumor activity and enhances the sensitivity of bortezomib in resistant multiple myeloma by inhibiting STAT3-dependent PSMB5 regulation 期刊论文  OAI收割
ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2023, 卷号: 55, 期号: 12, 页码: 1884-1891
作者:  
Jin, Shuhan;  Li, Bo;  Zhang, Bibo;  Gao, Xuejie;  Jia, Xinyan
  |  收藏  |  浏览/下载:8/0  |  提交时间:2024/02/27
The novel norcantharidin derivative DCZ5417 suppresses multiple myeloma progression by targeting the TRIP13-MAPK-YWHAE signaling pathway 期刊论文  OAI收割
JOURNAL OF TRANSLATIONAL MEDICINE, 2023, 卷号: 21, 期号: 1, 页码: 17
作者:  
Wang, Yingcong;  Dong, Sanfeng;  Hu, Ke;  Xu, Li;  Feng, Qilin
  |  收藏  |  浏览/下载:12/0  |  提交时间:2024/01/26
TI17, a novel compound, exerts anti-MM activity by impairing Trip13 function of DSBs repair and enhancing DNA damage 期刊论文  OAI收割
CANCER MEDICINE, 2023, 页码: 14
作者:  
Chang, Shuaikang;  Xiao, Wenqin;  Xie, Yongsheng;  Xu, Zhijian;  Li, Bo
  |  收藏  |  浏览/下载:7/0  |  提交时间:2023/12/11