中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [46]
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期刊论文 [56]
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A novel pterostilbene compound DCZ0825 induces macrophage M1 differentiation and Th1 polarization to exert anti-myeloma and immunomodulatory
期刊论文
OAI收割
INTERNATIONAL IMMUNOPHARMACOLOGY, 2024, 卷号: 127, 页码: 14
作者:
Zhang, Hui
;
Hu, Ke
;
Lu, Yumeng
;
Xu, Zhijian
;
Chen, Gege
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/03/25
Multiple myeloma
M1 macrophages
Th1 cells
Immunomodulatory
Design and synthesis of cantharidin derivative DCZ5418 as a TRIP13 inhibitor with anti-multiple myeloma activity
in
vitro
and
in
vivo
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2024, 卷号: 98, 页码: 7
作者:
Dong, Sanfeng
;
Hu, Ke
;
Shi, Yulong
;
Wang, Guanli
;
Yu, Dandan
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/02/19
Multiple myeloma
TRIP13 inhibitor
Cantharidin
DCZ5418
DCZ0415
The novel norcantharidin derivative DCZ5417 suppresses multiple myeloma progression by targeting the TRIP13-MAPK-YWHAE signaling pathway
期刊论文
OAI收割
JOURNAL OF TRANSLATIONAL MEDICINE, 2023, 卷号: 21, 期号: 1, 页码: 17
作者:
Wang, Yingcong
;
Dong, Sanfeng
;
Hu, Ke
;
Xu, Li
;
Feng, Qilin
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/01/26
Norcantharidin
Derivative
DCZ5417
TRIP13
Anti-myeloma
MAPK
TI17, a novel compound, exerts anti-MM activity by impairing Trip13 function of DSBs repair and enhancing DNA damage
期刊论文
OAI收割
CANCER MEDICINE, 2023, 页码: 14
作者:
Chang, Shuaikang
;
Xiao, Wenqin
;
Xie, Yongsheng
;
Xu, Zhijian
;
Li, Bo
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2023/12/11
DNA damage
DSBs repair
myeloma
TI17
Trip13
Molecular mechanism by which RRM2-inhibitor (cholagogue osalmid) plus bafilomycin A1 cause autophagic cell death in multiple myeloma
期刊论文
OAI收割
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 2023, 卷号: 747, 页码: 12
作者:
Guo, Shushan
;
Xu, Zhijian
;
Feng, Qilin
;
Zhang, Hui
;
Yu, Dandan
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2023/12/11
Autophagy
RRM2
p62
RIPK3
Cholagogue osalmid
Bafilomycin A1
Design, synthesis, and biological evaluation of BRD4 degraders
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 78, 页码: 12
作者:
Ding, Mengyuan
;
Shao, Yingying
;
Sun, Danwen
;
Meng, Suorina
;
Zang, Yi
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2023/04/10
PROTAC
BRD4 degradation
Leukemia
Multiple myeloma
Pulmonary fibrosis
Structural Modification and Pharmacological Evaluation of Substituted Quinoline-5,8-diones as Potent NSD2 Inhibitors
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 18
作者:
Tang, Hairong
;
Yu, Aisong
;
Xing, Li
;
Chen, Xiaoyu
;
Ding, Huaqian
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2023/04/10
Traditional Chinese Medicine Targeting Sarcoma Virus Oncogene-related Diseases
期刊论文
OAI收割
CURRENT CANCER DRUG TARGETS, 2023, 卷号: 23, 期号: 10, 页码: 751-763
作者:
Wang, Yiying
;
Wang, Xiaoyu
;
Su, Kexin
;
Yang, Yifu
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/10/17
c-Src
natural compounds
traditional chinese medicine
cancer
inflammation
osteoblast
Preclinical validation and phase I trial of 4-hydroxysalicylanilide, targeting ribonucleotide reductase mediated dNTP synthesis in multiple myeloma
期刊论文
OAI收割
Journal of Biomedical Science, 2022, 卷号: 29, 期号: 1
作者:
Xie,Yongsheng
;
Wang,Yingcong
;
Xu,Zhijian
;
Lu,Yumeng
;
Song,Dongliang
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2022/06/15
4-Hydroxysalicylanilid
Ribonucleotide reductase
Deoxyribonucleotides
DNA damage repair
Multiple myeloma
Design, synthesis and biological evaluation of sulfonamides inhibitors of XPO1 displaying activity against multiple myeloma cells
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 235
作者:
Qu, Bingxue
;
Xu, Yongjin
;
Lu, Yang
;
Zhuang, Weihao
;
Jin, Xinxin
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2022/12/23
XPO1
Multiple myeloma
MM.1S
N-phenylsulfonamide
Oral administration