机构

• 上海药物研究所 [126]

采集方式

• OAI收割 [126]

内容类型

• 期刊论文 [125]
• 会议论文 [1]

发表日期

• 2024 [1]
• 2023 [10]
• 2022 [9]
• 2021 [19]
• 2020 [14]
• 2019 [4]
• 更多

学科主题

• Chemistry [2]
• Biochemist... [1]
• Plant Scie... [1]
• Spectrosco... [1]

筛选

浏览/检索结果: 共126条，第1-10条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 A novel strategy for treating oncogene-mutated tumors by targeting tumor microenvironment and synergistically enhancing anti-PD-1 immunotherapy 期刊论文  OAI收割 CANCER COMMUNICATIONS, 2024, 页码: 5 作者:  Liu, Yingqiang;  Tong, Linjiang;  Zhang, Mengge;  Zhang, Qi;  Liu, Qiupei   |  收藏  |  浏览/下载：13/0  |  提交时间：2024/03/13 Autoimmune diseases: targets, biology, and drug discovery 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2023, 页码: 12 作者:  Li, Shu-jie;  Wu, Yan-li;  Chen, Juan-hua;  Shen, Shi-yi;  Duan, Jia   |  收藏  |  浏览/下载：6/0  |  提交时间：2024/01/26 autoimmune disease  autoantigen  immunotherapy  type 1 diabetes  insulin  drug discovery   Qing-Zhi-Tiao-Gan-Tang (QZTGT) prevents nonalcoholic steatohepatitis (NASH) by expression pattern correction 期刊论文  OAI收割 JOURNAL OF ETHNOPHARMACOLOGY, 2023, 卷号: 317, 页码: 14 作者:  Chu, Hang;  Zhang, Weitao;  Tan, Yan;  Diao, Zhipeng;  Li, Peng   |  收藏  |  浏览/下载：22/0  |  提交时间：2023/10/17 Fibrosis  Inflammation  Lipogenesis  NASH  QZTGT  TMNP   Preclinical and early clinical studies of a novel compound SYHA1813 that efficiently crosses the blood-brain barrier and exhibits potent activity against glioblastoma 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 12, 页码: 4748-4764 作者:  Liu, Yingqiang;  Zhan, Zhengsheng;  Kang, Zhuang;  Li, Mengyuan;  Lv, Yongcong   |  收藏  |  浏览/下载：9/0  |  提交时间：2024/01/26 Small molecule inhibitor  Tumor microenvironment  Immune-checkpoint  immune-deficient mouse models  including temozolomide (TMZ) insensitive tumors. Notably   Design and synthesis of 1H-pyrazolo[3,4-d]pyrimidine derivatives as hematopoietic progenitor kinase 1 (HPK1) inhibitors 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2023, 卷号: 140, 页码: 18 作者:  Zhang, Junjie;  Li, Yan;  Tang, Haotian;  Zhou, Qianqian;  Tong, Linjiang   |  收藏  |  浏览/下载：8/0  |  提交时间：2023/12/08 Cancer immunotherapy  HPK1  Structure -based design  HPK1 inhibitor   The PIWI-specific insertion module helps load longer piRNAs for translational activation essential for male fertility 期刊论文  OAI收割 SCIENCE CHINA-LIFE SCIENCES, 2023, 页码: 23 作者:  Wang, Xin;  Lin, Di-Hang;  Yan, Yue;  Wang, An-Hui;  Liao, Jiaoyang   |  收藏  |  浏览/下载：21/0  |  提交时间：2023/10/17 PIWI  piRNAs  PIWI-Ins  translational activation  spermatid development  male fertility   Development of a series of quinazoline-2,5-diamine derivatives as potent hematopoietic progenitor kinase 1 (HPK1) inhibitors 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 248, 页码: 20 作者:  Shi, Huanyu;  Tang, Haotian;  Li, Yan;  Chen, Danqi;  Liu, Tongchao   |  收藏  |  浏览/下载：19/0  |  提交时间：2023/04/10 Cancer immunotherapy  SAR study  HPK1 inhibitors  Quinazoline-2  5-diamine  IL-2 production   Thioparib inhibits homologous recombination repair, activates the type I IFN response, and overcomes olaparib resistance 期刊论文  OAI收割 EMBO MOLECULAR MEDICINE, 2023, 页码: 24 作者:  Wang, Li-Min;  Wang, Pingyuan;  Chen, Xiao-Min;  Yang, Hui;  Song, Shan-Shan   |  收藏  |  浏览/下载：21/0  |  提交时间：2023/04/10 homologous recombination repair  olaparib-resistant  PARP inhibitor  PARP7  type I interferons   Extracellular vesicles mediate antibody-resistant transmission of SARS-CoV-2 期刊论文  OAI收割 CELL DISCOVERY, 2023, 卷号: 9, 期号: 1, 页码: 15 作者:  Xia, Bingqing;  Pan, Xiaoyan;  Luo, Rong-Hua;  Shen, Xurui;  Li, Shuangqu   |  收藏  |  浏览/下载：30/0  |  提交时间：2023/04/10 Intranasal delivery of replicating mRNA encoding hACE2-targeting antibody against SARS-CoV-2 Omicron infection in the hamster 期刊论文  OAI收割 ANTIVIRAL RESEARCH, 2023, 卷号: 209, 页码: 9 作者:  Zhang, Ya-Nan;  Zhang, Hong-Qing;  Wang, Gui-Feng;  Zhang, Zhe-Rui;  Li, Jia-Qi   |  收藏  |  浏览/下载：18/0  |  提交时间：2023/04/10 Omicron  VEEV VRP  Replicable mRNA