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Structure-based development of potent and selective type-II kinase inhibitors of RIPK1 期刊论文  OAI收割
ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 1, 页码: 319-334
作者:  Qin, Ying;  Li, Dekang;  Qi, Chunting;  Xiang, Huaijiang;  Meng, Huyan
  |  收藏  |  浏览/下载：6/0  |  提交时间：2024/03/06
Anxiolytic effect of antidiabetic metformin is mediated by AMPK activation in mPFC inhibitory neurons 期刊论文  OAI收割
MOLECULAR PSYCHIATRY, 2023, 页码: 11
作者:  Zhang, Yong-mei;  Zong, Hai-chao;  Qi, Ying-bei;  Chang, Liu-liu;  Gao, Ya-nan
  |  收藏  |  浏览/下载：10/0  |  提交时间：2023/12/08
Discovery of 7H-Pyrrolo[2,3-d]pyrimidine Derivatives as potent hematopoietic progenitor kinase 1 (HPK1) inhibitors 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 254, 页码: 15
作者:  Wu, Feifei;  Li, Huiyu;  An, Qi;  Sun, Yaoliang;  Yu, Jinghua
  |  收藏  |  浏览/下载：9/0  |  提交时间：2023/10/17
Peptide-functionalized therapeutic nanoplatform for treatment orthotopic triple negative breast cancer and bone metastasis 期刊论文  OAI收割
NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE, 2023, 卷号: 50, 页码: 102669
作者:  Li, Daifeng;  Ma, Shengnan;  Xu, Denghui;  Meng, Xiaocao;  Lei, Ningjing
  |  收藏  |  浏览/下载：5/0  |  提交时间：2024/03/27
Covalent inhibitor targets KRasG12C: A new paradigm for drugging the undruggable and challenges ahead 期刊论文  OAI收割
GENES & DISEASES, 2023, 卷号: 10, 期号: 2, 页码: 403-414
作者:  Li, Hui-yu;  Qi, Wei-liang;  Wang, Yu-xiang;  Meng, Ling-hua
  |  收藏  |  浏览/下载：117/0  |  提交时间：2023/10/17
Targeting PI3K alpha overcomes resistance to KRas(G12C) inhibitors mediated by activation of EGFR and/or IGF1R 期刊论文  OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 页码: 12
作者:  Qi, Wei-liang;  Li, Hui-yu;  Wang, Yi;  Xu, Lan;  Deng, Jie-ting
  |  收藏  |  浏览/下载：15/0  |  提交时间：2023/04/10
Mechanistic Study on the Species Differences in Excretion Pathway of HR011303 in Humans and Rats 期刊论文  OAI收割
DRUG METABOLISM AND DISPOSITION, 2022, 卷号: 50, 期号: 6, 页码: 809-818
作者:  Guo, Zitao;  Liu, Mengling;  Meng, Jian;  Xue, Yaru;  Huang, Qi
  |  收藏  |  浏览/下载：25/0  |  提交时间：2022/08/16
Alpinia hainanensis Rhizome Extract Ameliorates Dextran Sulfate Sodium-Induced Ulcerative Colitis: Active Ingredient Investigation and Evaluation 期刊论文  OAI收割
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2022, 卷号: 70, 期号: 13, 页码: 3989-3999
作者:  Ji, Kai-Long;  Wu, Meng-Zhen;  Huang, Chao-Ying;  Gongpan, Pian-Chou;  Sun, Peng
  |  收藏  |  浏览/下载：28/0  |  提交时间：2022/06/15
Safety, tolerability, and pharmacokinetics of VV116, an oral nucleoside analog against SARS-CoV-2, in Chinese healthy subjects 期刊论文  OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 页码: 9
作者:  Qian, Hong-jie;  Wang, Yu;  Zhang, Meng-qi;  Xie, Yuan-chao;  Wu, Qing-qing
  |  收藏  |  浏览/下载：37/0  |  提交时间：2022/06/15
Downregulation of c-Myc expression confers sensitivity to CHK1 inhibitors in hematologic malignancies 期刊论文  OAI收割
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:  Jiang, Kai-long;  Tong, Le-xian;  Wang, Tao;  Wang, Han-lin;  Hu, Xiao-bei
  |  收藏  |  浏览/下载：48/0  |  提交时间：2021/05/24