中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [58]
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OAI收割 [58]
内容类型
期刊论文 [56]
会议论文 [2]
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2024 [1]
2023 [3]
2022 [3]
2021 [6]
2020 [5]
2019 [4]
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浏览/检索结果:
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专题:上海药物研究所
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Second messenger 2'3'-cyclic GMP-AMP (2'3'-cGAMP): the cell autonomous and non-autonomous roles in cancer progression
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 10
作者:
Ma, Xiao-yu
;
Chen, Man-man
;
Meng, Ling-hua
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2024/02/27
CDNs
2'3'-cGAMP
cGAS-STING
tumor microenvironment
ENPP1
TREX1
Covalent inhibitor targets KRasG12C: A new paradigm for drugging the undruggable and challenges ahead
期刊论文
OAI收割
GENES & DISEASES, 2023, 卷号: 10, 期号: 2, 页码: 403-414
作者:
Li, Hui-yu
;
Qi, Wei-liang
;
Wang, Yu-xiang
;
Meng, Ling-hua
  |  
收藏
  |  
浏览/下载:117/0
  |  
提交时间:2023/10/17
Biomarkers
Covalent KRasG12Cinhibitors
Drug resistance
Human cancers
KRASG12Cmutation
Single-cell RNA sequencing reveals the suppressive effect of PPP1R15A inhibitor Sephin1 in antitumor immunity
期刊论文
OAI收割
ISCIENCE, 2023, 卷号: 26, 期号: 2, 页码: 27
作者:
Wang, Rongjing
;
Zhang, Yuchao
;
Guo, Shiwei
;
Pei, Siyu
;
Guo, Wei
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2023/10/17
Xanthine dehydrogenase rewires metabolism and the survival of nutrient deprived lung adenocarcinoma cells by facilitating UPR and autophagic degradation
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 2023, 卷号: 19, 期号: 3, 页码: 772-788
作者:
Chen, Man-man
;
Guo, Wei
;
Chen, Si-meng
;
Guo, Xiao-zhen
;
Xu, Lan
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/03/27
Xanthine dehydrogenase
nucleoside degradation
cell survival
UPR
autophagy
LUAD
Targeting PI3K alpha overcomes resistance to KRas(G12C) inhibitors mediated by activation of EGFR and/or IGF1R
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 页码: 12
作者:
Qi, Wei-liang
;
Li, Hui-yu
;
Wang, Yi
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2023/04/10
AMG510
KRas(G12C)
PI3K
drug resistance
combination therapy
Loss of SIRT5 promotes bile acid-induced immunosuppressive microenvironment and hepatocarcinogenesis
期刊论文
OAI收割
JOURNAL OF HEPATOLOGY, 2022, 卷号: 77, 期号: 2, 页码: 453-466
作者:
Sun, Renqiang
;
Zhang, Zhiyong
;
Bao, Ruoxuan
;
Guo, Xiaozhen
;
Gu, Yuan
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/03/21
SIRT5
bile acid
macrophage polarization
immunosuppressive tumor microenvironment
liver cancer
Repressing MYC by targeting BET synergizes with selective inhibition of PI3K alpha against B cell lymphoma
期刊论文
OAI收割
CANCER LETTERS, 2022, 卷号: 524, 页码: 206-218
作者:
Chen, Zi-qi
;
Cao, Zhe-rui
;
Wang, Yi
;
Zhang, Xi
;
Xu, Lan
  |  
收藏
  |  
浏览/下载:54/0
  |  
提交时间:2021/12/16
CYH33
MYC
P300
BET
B cell lymphoma
PI3K
The double faced role of xanthine oxidoreductase in cancer
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 10
作者:
Chen, Man-Man
;
Meng, Ling-Hua
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2022/01/04
xanthine oxidoreductase (XOR)
ROS
uric acid
cancer therapy
SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damages and constitutes an antiviral target
期刊论文
OAI收割
CELL RESEARCH, 2021, 页码: 14
作者:
Xia, Bingqing
;
Shen, Xurui
;
He, Yang
;
Pan, Xiaoyan
;
Liu, Feng-Liang
  |  
收藏
  |  
浏览/下载:74/0
  |  
提交时间:2021/08/17
SAF-248, a novel PI3K delta-selective inhibitor, potently suppresses the growth of diffuse large B-cell lymphoma
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11
作者:
Zhang, Xi
;
Duan, Yu-ting
;
Wang, Yi
;
Zhao, Xing-dong
;
Sun, Yi-ming
  |  
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2021/05/24
PI3Kδ
PI3K
AKT
mTOR
diffuse large B-cell lymphoma
resistance
combination therapy