中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [20]
采集方式
OAI收割 [20]
内容类型
期刊论文 [20]
发表日期
2024 [1]
2023 [3]
2022 [5]
2021 [1]
2020 [1]
2018 [1]
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Chemistry [1]
Pharmacolo... [1]
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专题:上海药物研究所
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Reversible SAHH inhibitor ameliorates MIA-induced osteoarthritis of rats through suppressing MEK/ERK pathway
期刊论文
OAI收割
BIOMEDICINE & PHARMACOTHERAPY, 2024, 卷号: 170, 页码: 6
作者:
Fan, Shu-Hui
;
Chang, Yuan
;
Xiong, Xiao-Yu
;
Xiang, Mai
;
Yuan, Wen-Long
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/02/27
DZ2002
Osteoarthritis
Osteoclast
Bone resorption
Prime editing-based gene correction alleviates the hyperexcitable phenotype and seizures of a genetic epilepsy mouse model
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 4
作者:
Cao, Bi-rong
;
Huang, Yi-ming
;
Tian, Fu-yun
;
Li, Jin-hui
;
Xu, Chun-long
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2023/10/17
Carbohydrate Strengthens the Immunotherapeutic Effect of Small-Molecule PD-L1 Inhibitors
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 11, 页码: 7179-7204
作者:
Dong, Qian
;
Tong, Mengya
;
Yu, Xiaolu
;
Wang, Lei
;
Ao, Jiwei
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2023/10/17
Development of the novel ACLY inhibitor 326E as a promising treatment for hypercholesterolemia
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 2, 页码: 739-753
作者:
Xie, Zhifu
;
Zhang, Mei
;
Song, Qian
;
Cheng, Long
;
Zhang, Xinwen
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/03/27
Hypercholesterolemia
Atherosclerosis
Liver
ATP-Citrate lyase (ACLY)
Lipogenesis
Cholesterol efflux
ACLY inhibitor
Mass spectrometry imaging: new eyes on natural products for drug research and development
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 页码: 16
作者:
Hou, Jin-jun
;
Zhang, Zi-jia
;
Wu, Wen-yong
;
He, Qing-qing
;
Zhang, Teng-qian
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2022/11/11
natural product
mass spectrometry imaging
MALDI
DESI
molecular imaging
ion mobility
Diterpenoids from Sauropus spatulifolius Leaves with Antimicrobial Activities
期刊论文
OAI收割
JOURNAL OF NATURAL PRODUCTS, 2022, 卷号: 85, 期号: 5, 页码: 1304-1314
作者:
Wu, Pei-Qian
;
Cui, Yong-Sheng
;
Han, Xiao-Ying
;
Wang, Chen
;
An, Pei-Pei
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2022/08/16
In-depth exploration and comparison of chemical constituents from two Lilium species through offline two-dimensional liquid chromatography combined with multimode acquisition of high-resolution mass spectrometry
期刊论文
OAI收割
JOURNAL OF CHROMATOGRAPHY A, 2022, 卷号: 1670, 页码: 11
作者:
Wu, Xingdong
;
Hou, Jinjun
;
Zhang, Zijia
;
Chen, Lingmin
;
Ni, Hui
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2022/08/16
Offline 2D LC
Comparative components
Phenylpropanoid derivatives
Steroidal saponins
Lilium
Targeting the RT loop of Src SH3 in Platelets Prevents Thrombosis without Compromising Hemostasis
期刊论文
OAI收割
ADVANCED SCIENCE, 2022, 卷号: 9, 期号: 7, 页码: 2103228
作者:
Mao, Jianhua
;
Zhu, Kongkai
;
Long, Zhangbiao
;
Zhang, Huimin
;
Xiao, Bing
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2024/03/21
antithrombotic target
bleeding risk
E97A knock-in mice
small molecule
beta 3/Src interaction
Atractylenolide III ameliorates Non-Alcoholic Fatty Liver Disease by activating Hepatic Adiponectin Receptor 1-Mediated AMPK Pathway
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 2022, 卷号: 18, 期号: 4, 页码: 1594-1611
作者:
Li, Qian
;
Tan, Jia-Xin
;
He, Yong
;
Bai, Fang
;
Li, Shi-Wei
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2022/06/15
ATL III
AdipoR1
oxidative stress
inflammation
AMPK
SIRT1
Amygdalar k-opioid receptor-dependent upregulating glutamate transporter 1 mediates depressive-like behaviors of opioid abstinence
期刊论文
OAI收割
CELL REPORTS, 2021, 卷号: 37, 期号: 5, 页码: 21
作者:
Zan, Gui-Ying
;
Wang, Yu-Jun
;
Li, Xue-Ping
;
Fang, Jun-Fan
;
Yao, Song-Yu
  |  
收藏
  |  
浏览/下载:56/0
  |  
提交时间:2021/12/16