机构

• 上海药物研究所 [69]

采集方式

• OAI收割 [69]

内容类型

• 期刊论文 [69]

发表日期

• 2024 [1]
• 2023 [5]
• 2022 [5]
• 2021 [7]
• 2020 [4]
• 2019 [3]
• 更多

学科主题

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浏览/检索结果: 共69条，第1-10条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Nanobodies as negative allosteric modulators for human calcium sensing receptor 期刊论文  OAI收割 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2024, 卷号: 695, 页码: 9 作者:  Cui, Qianqian;  Wang, Lu;  Wang, Haonan;  Chen, Xiaochen;  Han, Li   |  收藏  |  浏览/下载：16/0  |  提交时间：2024/04/09 G-protein-coupled receptor  Extracellular calcium sensing receptor  Nanobody  Cryo-electron microscope  Systemic Ca 2+homoeostasis   Preclinical and early clinical studies of a novel compound SYHA1813 that efficiently crosses the blood-brain barrier and exhibits potent activity against glioblastoma 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 12, 页码: 4748-4764 作者:  Liu, Yingqiang;  Zhan, Zhengsheng;  Kang, Zhuang;  Li, Mengyuan;  Lv, Yongcong   |  收藏  |  浏览/下载：9/0  |  提交时间：2024/01/26 Small molecule inhibitor  Tumor microenvironment  Immune-checkpoint  immune-deficient mouse models  including temozolomide (TMZ) insensitive tumors. Notably   Structure basis of two nanobodies neutralizing SARS-CoV-2 Omicron variant by targeting ultra-conservative epitopes 期刊论文  OAI收割 JOURNAL OF STRUCTURAL BIOLOGY, 2023, 卷号: 215, 期号: 3, 页码: 9 作者:  Sun, Zengchao;  Wang, Lu;  Li, Lingyun;  Sun, Yili;  Zhang, Daizhou   |  收藏  |  浏览/下载：12/0  |  提交时间：2023/10/17 SARS-CoV-2 virus  Receptor -binding domain  Nanobody  Crystal structure  Conservative binding epitope  Bi-paratopic nanobodies   A procedure for producing an anti-AXL nanobody in E. coli 期刊论文  OAI收割 PROTEIN EXPRESSION AND PURIFICATION, 2023, 卷号: 207, 页码: 106268 作者:  Lan, Zhongyun;  Li, Lingyun;  Sun, Yili;  Meng, Xiangjing;  Shi, Zhenzhong   |  收藏  |  浏览/下载：5/0  |  提交时间：2024/03/27 AXL  Nanobody  Expression  Purification   Sensitivity-enhanced nanoplasmonic biosensor using direct immobilization of two engineered nanobodies for SARS-CoV-2 spike receptor-binding domain detection 期刊论文  OAI收割 SENSORS AND ACTUATORS B-CHEMICAL, 2023, 卷号: 383, 页码: 133575 作者:  Ma, Zhengtai;  Sun, Zengchao;  Lv, Xiaoqing;  Chen, Hongda;  Geng, Yong   |  收藏  |  浏览/下载：4/0  |  提交时间：2024/03/27 Nanoplasmonics  Biosensor  COVID-19  Nanobody  Immobilization  High -throughput   Fine-tuning Bacterial Cyclic di-AMP Production for Durable Antitumor Effects Through the Activation of the STING Pathway 期刊论文  OAI收割 RESEARCH, 2023, 卷号: 6, 页码: 15 作者:  Jiang, Yu;  Li, Xiyuan;  Qian, Fenghui;  Sun, Bingbing;  Wang, Xiyuan   |  收藏  |  浏览/下载：22/0  |  提交时间：2023/10/17 Discovery of a potent and selective proteolysis targeting chimera (PROTAC) degrader of NSD3 histone methyltransferase 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 239, 页码: 18 作者:  Sun, Yaoliang;  Zhang, Ying;  Chen, Xiaoai;  Yu, Aisong;  Du, Wenhao   |  收藏  |  浏览/下载：41/0  |  提交时间：2022/08/30 NSD3  PROTAC  Degrader  Methyltransferase   Structure-Based of a Series of NSD2-PWWP1 Inhibitors 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 13, 页码: 9459-9477 作者:  Li, Na;  Yang, Hong;  Liu, Ke;  Zhou, Liwei;  Huang, Yuting   |  收藏  |  浏览/下载：9/0  |  提交时间：2024/03/21 Structural basis of nanobodies neutralizing SARS-CoV-2 variants 期刊论文  OAI收割 STRUCTURE, 2022, 卷号: 30, 期号: 5, 页码: 707-+ 作者:  Shi, Zhenzhong;  Li, Xiyang;  Wang, Lu;  Sun, Zengchao;  Zhang, Haiwei   |  收藏  |  浏览/下载：33/0  |  提交时间：2022/08/16 An extended conformation of SARS-CoV-2 main protease reveals allosteric targets 期刊论文  OAI收割 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2022, 卷号: 119, 期号: 15, 页码: 9 作者:  Sun, Zengchao;  Wang, Lu;  Li, Xiyang;  Fan, Chengpeng;  Xu, Jianfeng   |  收藏  |  浏览/下载：23/0  |  提交时间：2022/06/15 SARS-CoV-2 main protease  nanobody  M-pro extended conformation  M-pro compact conformation