机构

• 上海药物研究所 [26]

采集方式

• OAI收割 [26]

内容类型

• 期刊论文 [26]

发表日期

• 2024 [1]
• 2023 [8]
• 2022 [7]
• 2021 [2]
• 2019 [1]
• 2018 [1]
• 更多

学科主题

筛选

浏览/检索结果: 共26条，第1-10条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Discovery of GPX4 inhibitors through FP-based high-throughput screening 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 265, 页码: 14 作者:  Cao, Yu;  Wu, Bin;  Xu, Ying;  Wang, Mingchen;  Wu, Xinyu   |  收藏  |  浏览/下载：22/0  |  提交时间：2024/02/27 GPX4 inhibitor  HTS assay  Ferroptosis  Fluorescence polarization   Discovery of a novel OGT inhibitor through high-throughput screening based on Homogeneous Time-Resolved Fluorescence (HTRF) 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2023, 卷号: 139, 页码: 12 作者:  Wu, Xinyu;  Wang, Mingchen;  Cao, Yu;  Xu, Ying;  Yang, Ziqun   |  收藏  |  浏览/下载：2/0  |  提交时间：2024/02/27 O-GlcNAcylation  O-GlcNAc transferase  High-throughput screening  Inhibitor   Discovery of novel triazine derivatives as potent retinoic acid receptor-related orphan receptor gamma t (ROR gamma t) inverse agonists 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 256, 页码: 18 作者:  Lu, Lixue;  Chen, Song;  Yu, Mingcheng;  Zhou, Ronghui;  Guo, Siqi   |  收藏  |  浏览/下载：16/0  |  提交时间：2023/10/17 ROR gamma t  Triazines  Inverse agonist  Psoriasis  Autoimmune diseases   YTHDF2 inhibition potentiates radiotherapy antitumor efficacy 期刊论文  OAI收割 CANCER CELL, 2023, 卷号: 41, 期号: 7, 页码: 1294-+ 作者:  Wang, Liangliang;  Dou, Xiaoyang;  Chen, Shijie;  Yu, Xianbin;  Huang, Xiaona   |  收藏  |  浏览/下载：21/0  |  提交时间：2023/10/17 RNAincoder: a deep learning-based encoder for RNA and RNA-associated interaction 期刊论文  OAI收割 NUCLEIC ACIDS RESEARCH, 2023, 页码: 11 作者:  Wang, Yunxia;  Chen, Zhen;  Pan, Ziqi;  Huang, Shijie;  Liu, Jin   |  收藏  |  浏览/下载：19/0  |  提交时间：2023/10/17 Optimization of carbazole carboxamide RORγt agonists: Challenges in improving the metabolic stability and maintaining the agonistic activity 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 251, 页码: 115213 作者:  Sun, Nannan;  Yu, Mingcheng;  Jiang, Zhengyuan;  Yang, Feng;  Lu, Lixue   |  收藏  |  浏览/下载：1/0  |  提交时间：2024/03/27 ROR?t agonists  Carbazole carboxamide  Agonistic activity  Metabolic stability  Co-crystallization  Molecular docking   Discovery of new small molecule inhibitors of the BPTF bromodomain 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2023, 卷号: 134, 页码: 106453 作者:  Liang, Xiaochen;  Cao, Yu;  Duan, Zhe;  Wang, Mingchen;  Zhang, Naixia   |  收藏  |  浏览/下载：2/0  |  提交时间：2024/03/27 BPTF bromodomain  BPTF inhibitors  HTRF  c-Myc   Selective PPAR gamma modulator diosmin improves insulin sensitivity and promotes browning of white fat 期刊论文  OAI收割 JOURNAL OF BIOLOGICAL CHEMISTRY, 2023, 卷号: 299, 期号: 4, 页码: 14 作者:  Yu, Jian;  Hu, Yepeng;  Sheng, Maozheng;  Gao, Mingyuan;  Guo, Wenxiu   |  收藏  |  浏览/下载：23/0  |  提交时间：2023/10/17 Cyclization strategy leads to highly potent Bromodomain and extra-terminal (BET) Bromodomain inhibitors for the treatment of acute liver injury 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 247, 页码: 13 作者:  Chen, Chao;  Lu, Tian;  Chen, Panyu;  Li, Zizhou;  Yang, Yaxi   |  收藏  |  浏览/下载：24/0  |  提交时间：2023/04/10 BET Bromodomains  Acute liver injury  Anti-inflammatory activity  Inhibitors  Tetracyclic compounds   Design, synthesis, and biological evaluation of novel carbazole derivatives as potent DNMT1 inhibitors with reasonable PK properties 期刊论文  OAI收割 JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2022, 卷号: 37, 期号: 1, 页码: 1537-1555 作者:  Li, Ennian;  Wang, Kai;  Zhang, Bei;  Guo, Siqi;  Xiao, Senhao   |  收藏  |  浏览/下载：37/0  |  提交时间：2022/08/16 DNMT1 inhibitor  A549 cell lines  HCT116 cell lines  antitumor activity  pharmacokinetic