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Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [52]
生态环境研究中心 [35]
昆明植物研究所 [13]
大连化学物理研究所 [5]
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期刊论文 [119]
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Discovery of a CB2 and 5-HT1A receptor dual agonist for the treatment of depression and anxiety
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 265, 页码: 20
作者:
Yang, Wenjiao
;
Gong, Xudong
;
Sun, Haiguo
;
Wu, Chunhui
;
Suo, Jin
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/03/06
CB2R agonist
5-HT1AR agonist
CB1R antagonist
Antidepressant
Anxiolytic
Design, synthesis, and STING-agonistic activity of benzo[
b
]thiophene-2-carboxamide derivatives
期刊论文
OAI收割
MOLECULAR DIVERSITY, 2023, 页码: 10
作者:
Zhou, Rongyao
;
Wang, Xiyuan
;
Zhang, Deqiang
;
Zhan, Zhengsheng
;
Duan, Wenhu
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2023/12/08
STING
CDN
Benzo[b]thiophene-2-carboxamide
Cellular activity
Discovery of novel triazine derivatives as potent retinoic acid receptor-related orphan receptor gamma t (ROR gamma t) inverse agonists
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 256, 页码: 18
作者:
Lu, Lixue
;
Chen, Song
;
Yu, Mingcheng
;
Zhou, Ronghui
;
Guo, Siqi
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2023/10/17
ROR gamma t
Triazines
Inverse agonist
Psoriasis
Autoimmune diseases
Optimization of carbazole carboxamide RORγt agonists: Challenges in improving the metabolic stability and maintaining the agonistic activity
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 251, 页码: 115213
作者:
Sun, Nannan
;
Yu, Mingcheng
;
Jiang, Zhengyuan
;
Yang, Feng
;
Lu, Lixue
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/03/27
ROR?t agonists
Carbazole carboxamide
Agonistic activity
Metabolic stability
Co-crystallization
Molecular docking
Advances in Medicinal Chemistry of Estrogen-related Receptor Alpha (ERRa) Inverse Agonists
期刊论文
OAI收割
CURRENT TOPICS IN MEDICINAL CHEMISTRY, 2023, 卷号: 23, 期号: 20, 页码: 1952-1963
作者:
Zhang, Haibin
;
Du, Yongli
;
Zheng, Yong
;
Lv, Huiting
;
Yan, Zhijia
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2023/10/17
ERRalpha
ERRalpha inverse agonists
Breast cancer
TNBC
Signaling pathways
Inverse agonistic activity
Tox21-Based Comparative Analyses for the Identification of Potential Toxic Effects of Environmental Pollutants
期刊论文
OAI收割
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2022, 期号: 0, 页码: 1-12
作者:
Yang, Renjun
;
Liu, Shuyu
;
Yin, Nuoya
;
Zhang, Yang
;
Faiola, Francesco
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2022/11/08
ORGANOPHOSPHATE FLAME RETARDANTS
ESTROGEN-RECEPTOR
IN-VIVO
REPRODUCTIVE DEVELOPMENT
TETRABROMOBISPHENOL-A
ANDROGEN RECEPTOR
ER-BETA
PESTICIDES
ATRAZINE
XENOBIOTICS
Binding and Activation of Estrogen-Related Receptor ?: A Novel Molecular Mechanism for the Estrogenic Disruption Effects of DDT and Its Metabolites
期刊论文
OAI收割
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2022, 卷号: 56, 期号: 17, 页码: 12358-12367
作者:
Wang, Li
;
Qie, Yu
;
Yang, Yu
;
Zhao, Qiang
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2022/11/08
ERR-GAMMA
ALPHA
PESTICIDES
CANCER
Diversity-oriented synthesis of marine polybrominated diphenyl ethers as potential KCNQ potassium channel activators
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2022, 卷号: 126, 页码: 105909
作者:
Liu, Lai-Xin
;
Gu, Ru-Rong
;
Jin, Yang
;
Chen, Xue-Qin
;
Li, Xu-Wen
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/03/21
Marine Natural product
Polybrominated diphenyl ethers
KCNQ potassium channel
Alisol B Alleviates Hepatocyte Lipid Accumulation and Lipotoxicity via Regulating RAR alpha-PPAR gamma-CD36 Cascade and Attenuates Non-Alcoholic Steatohepatitis in Mice
期刊论文
OAI收割
NUTRIENTS, 2022, 卷号: 14, 期号: 12, 页码: 20
作者:
Zhao, Zhuohui
;
Deng, Zhen-Tao
;
Huang, Suling
;
Ning, Mengmeng
;
Feng, Ying
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2022/08/16
Alisol B
non-alcoholic steatohepatitis
RAR alpha
CD36
The role of the SLC6A3 3' UTR VNTR in nicotine effects on cognitive, affective, and motor function
期刊论文
OAI收割
PSYCHOPHARMACOLOGY, 2021, 页码: 19
作者:
Schroeder, Rebekka
;
Reuter, Martin
;
Fassbender, Kaja
;
Plieger, Thomas
;
Poulsen, Jessie
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2021/12/27
Nicotine
DAT
Smooth pursuit
Inhibition
Spontaneous blink rate
Proactive inhibition
Stop signal task
Individual differences