机构

• 上海药物研究所 [12]

采集方式

• OAI收割 [12]

内容类型

• 期刊论文 [12]

发表日期

• 2021 [1]
• 2020 [2]
• 2019 [1]
• 2018 [3]
• 2017 [1]
• 2016 [1]
• 更多

学科主题

筛选

浏览/检索结果: 共12条，第1-10条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Twin drug design, synthesis and evaluation of diosgenin derivatives as multitargeted agents for the treatment of vascular dementia 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 37, 页码: 16 作者:  Yang, Gui-Xiang;  Sun, Jia-Min;  Zheng, Lu-Lu;  Zhang, Li;  Li, Jie   |  收藏  |  浏览/下载：23/0  |  提交时间：2021/06/11 Vascular dementia  Diosgenin  Antioxidant  Anti-cholinesterase  Multi-target-directed ligands   Dual Mechanisms of Novel CD73-Targeted Antibody and Antibody-Drug Conjugate in Inhibiting Lung Tumor Growth and Promoting Antitumor Immune-Effector Function 期刊论文  OAI收割 MOLECULAR CANCER THERAPEUTICS, 2020, 卷号: 19, 期号: 11, 页码: 2340-2352 作者:  Jin, Rui;  Liu, Liang;  Xing, Yun;  Meng, Tao;  Ma, Lanping   |  收藏  |  浏览/下载：61/0  |  提交时间：2020/12/24 Species differences in the CYP3A-catalyzed metabolism of TPN729, a novel PDE5 inhibitor 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2020, 页码: 9 作者:  Tian, Qian-qian;  Zhu, Yun-ting;  Diao, Xing-xing;  Zhang, Xiang-lei;  Xu, Ye-chun   |  收藏  |  浏览/下载：26/0  |  提交时间：2020/12/24 PDE5 inhibitor  TPN729  M3  species difference  pharmacokinetics  metabolite identification   Exploration of the structure-activity relationship and druggability of novel oxazolidinone-based compounds as Gram-negative antibacterial agents 期刊论文  OAI收割 ARCHIV DER PHARMAZIE, 2019, 页码: 13 作者:  Ding, Shi;  Ji, Jing-Chao;  Zhang, Ming-Juan;  Yang, Yu-She;  Wang, Rui   |  收藏  |  浏览/下载：14/0  |  提交时间：2020/07/01 antibacterial activity  oxazolidine  QSAR   Discovery of novel selective GPR120 agonists with potent anti-diabetic activity by hybrid design 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 15, 页码: 2599-2604 作者:  Sheng, Ren;  Yang, Liu;  Zhang, Yanchun;  Xing, Enming;  Shi, Rui   |  收藏  |  浏览/下载：22/0  |  提交时间：2019/01/08 GPR120  Agonist biphenyl derivatives  OGTT  Type 2 diabetes   Activation of AhR with nuclear IKK alpha regulates cancer stem-like properties in the occurrence of radioresistance 期刊论文  OAI收割 CELL DEATH & DISEASE, 2018, 卷号: 9 作者:  Yan, Bin;  Liu, Shuang;  Shi, Ying;  Liu, Na;  Chen, Ling   |  收藏  |  浏览/下载：108/0  |  提交时间：2019/01/08 Isolation, identification and bioactivities of abietane diterpenoids from Premna szemaoensis 期刊论文  OAI收割 RSC ADVANCES, 2018, 卷号: 8, 期号: 12, 页码: 6425-6435 作者:  Pu, De-Bing;  Wang, Ting;  Zhang, Xing-Jie;  Gao, Jun-Bo;  Zhang, Rui-Han   |  收藏  |  浏览/下载：14/0  |  提交时间：2019/01/08 Dissociative role for dorsal hippocampus in mediating heroin self-administration and relapse through CDK5 and RhoB signaling revealed by proteomic analysis 期刊论文  OAI收割 ADDICTION BIOLOGY, 2017, 卷号: 22, 期号: 6, 页码: 1731-1742 作者:  Chen, Zhong-Guo;  Liu, Xing;  Wang, Weisheng;  Geng, Fan;  Gao, Jing   |  收藏  |  浏览/下载：29/0  |  提交时间：2019/01/08 CDK5  dorsal hippocampus  heroin self-administration  label-free proteomic analysis  RhoB  the centrifugal proteomic reactor   Discovery and structural optimization of 4-(4-(benzyloxy) phenyl)-3,4-dihydropyrimidin-2(1H)-ones as RORc inverse agonists 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2016, 卷号: 37, 期号: 11, 页码: 1516 作者:  Wu Xishan;  Wang Rui;  Xing Yanli;  Xue Xiaoqian;  Zhang Yan   |  收藏  |  浏览/下载：83/0  |  提交时间：2020/12/24 GAMMA-T  ORPHAN RECEPTORS  CELL-DIFFERENTIATION  LIGAND  IDENTIFICATION  MODULATORS  DERIVATIVES  PROTEIN  INHIBITORS  DOCKING  nuclear receptor  RORc  inverse agonist  SAR  structure-based optimization  autoimmune disease   Epirubicin-Loaded Superparamagnetic Iron-Oxide Nanoparticles for Transdermal Delivery: Cancer Therapy by Circumventing the Skin Barrier 期刊论文  OAI收割 SMALL, 2015, 卷号: 11, 期号: 2, 页码: 239-247 作者:  Rao, Yue-feng;  Chen, Wei;  Liang, Xing-guang;  Huang, Yong-zhuo;  Miao, Jing   |  收藏  |  浏览/下载：15/0  |  提交时间：2019/01/08 superparamagnetic materials  iron oxide  nanoparticles  drug delivery  epirubicin  cancer  biomedical applications