机构

• 上海药物研究所 [248]

采集方式

• OAI收割 [248]

内容类型

• 期刊论文 [244]
• 会议论文 [4]

发表日期

• 2024 [1]
• 2023 [12]
• 2022 [20]
• 2021 [19]
• 2020 [13]
• 2019 [23]
• 更多

学科主题

• Biochemist... [3]
• Life Scien... [2]
• Endocrinol... [1]

筛选

浏览/检索结果: 共248条，第1-10条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Ent-labdane-type diterpene glycosides obtained from Rubus chingii Hu and their inhibitory effects on PDE5A activity 期刊论文  OAI收割 FITOTERAPIA, 2024, 卷号: 173, 页码: 14 作者:  Yu, Jun-dong;  Wang, Jing-Yi;  Liu, Jia-yuan;  Xu, Ye-chun;  Zhang, Xue   |  收藏  |  浏览/下载：9/0  |  提交时间：2024/02/27 diterpene glycosides  Rubus Chingii Hu  PDE5A inhibitory activity  ent-labdane   Safety, tolerability and pharmacokinetics of forsythin in healthy subjects: a double-blinded, placebo-controlled single-dose and multiple-dose escalation and food effect study 期刊论文  OAI收割 ANNALS OF MEDICINE, 2023, 卷号: 55, 期号: 2, 页码: 9 作者:  Li, Cuiyun;  Wu, Min;  Zhang, Hong;  Zhu, Xiaoxue;  Fu, Li   |  收藏  |  浏览/下载：22/0  |  提交时间：2024/01/16 Forsythin  pharmacokinetics  safety  tolerability  food effect   Discovery of zolinium TSG1180 as a novel agonist of transgelin-2 for treating asthma 期刊论文  OAI收割 Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, 卷号: 167, 页码: 115556 作者:  Yuan, Hong-Kai;  Li, Bo;  Wu, Leyun;  Wang, Xue-Ling;  Lv, Zhi-Ying   |  收藏  |  浏览/下载：8/0  |  提交时间：2024/03/26 Active learning  Consensus labelling  Eye irritation  Serious eye damage  Structural alerts   Discovery of a highly potent NPAS3 heterodimer inhibitor by covalently modifying ARNT 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2023, 卷号: 139, 页码: 10 作者:  Li, Peizhuo;  Tian, Yucheng;  Shang, Qinghong;  Tang, Cailing;  Hou, Zeng   |  收藏  |  浏览/下载：21/0  |  提交时间：2023/10/17 NPAS3  Covalent inhibitor  Protein -protein interaction  5-nitrothiazole warhead   LINC00955 suppresses colorectal cancer growth by acting as a molecular scaffold of TRIM25 and Sp1 to Inhibit DNMT3B-mediated methylation of the PHIP promoter 期刊论文  OAI收割 BMC CANCER, 2023, 卷号: 23, 期号: 1, 页码: 20 作者:  Ren, Ganglin;  Li, Hongyan;  Hong, Dan;  Hu, Fangyu;  Jin, Rongjia   |  收藏  |  浏览/下载：6/0  |  提交时间：2023/12/08 LINC00955  Colorectal cancer  Cell cycle  CDK2  PHIP  Sp1   Conserved class B GPCR activation by a biased intracellular agonist 期刊论文  OAI收割 NATURE, 2023, 页码: 25 作者:  Zhao, Li-Hua;  He, Qian;  Yuan, Qingning;  Gu, Yimin;  He, Xinheng   |  收藏  |  浏览/下载：10/0  |  提交时间：2023/10/17 Human-Induced Hepatocytes-Derived Extracellular Vesicles Ameliorated Liver Fibrosis in Mice Via Suppression of TGF-beta 1/Smad Signaling and Activation of Nrf2/HO-1 Signaling 期刊论文  OAI收割 STEM CELLS AND DEVELOPMENT, 2023, 页码: 14 作者:  Liu, Wenjing;  Wu, Jiajun;  Cao, Huiying;  Ma, Chen;  Wu, Zhitao   |  收藏  |  浏览/下载：25/0  |  提交时间：2023/10/17 hepatic stellate cell activation  liver fibrosis  extracellular vesicles  human-induced hepatocyte  TGF-beta 1/Smad pathway  Nrf2/HO-1 pathway   Effect of an Herbal-Based Injection on 28-Day Mortality in Patients With Sepsis The EXIT-SEP Randomized Clinical Trial 期刊论文  OAI收割 JAMA INTERNAL MEDICINE, 2023, 卷号: 183, 期号: 7, 页码: 647-655 作者:  Liu, Songqiao;  Yao, Chen;  Xie, Jianfeng;  Liu, Hong;  Wang, Hongliang   |  收藏  |  浏览/下载：4/0  |  提交时间：2024/03/27 A RhoA structure with switch II flipped outward revealed the conformational dynamics of switch II region 期刊论文  OAI收割 JOURNAL OF STRUCTURAL BIOLOGY, 2023, 卷号: 215, 期号: 2, 页码: 107942 作者:  Jiang, Hao;  Zu, Shijia;  Lu, Yu;  Sun, Zhongya;  Adeerjiang, Akejiang   |  收藏  |  浏览/下载：5/0  |  提交时间：2024/03/27 Small GTPases  Crystal structures of RhoA  Dynamics of switch II  Molecular dynamics simulations  Allosteric pocket   Structural Optimization of Fibroblast Growth Factor Receptor Inhibitors for Treating Solid Tumors 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 5, 页码: 3226-3249 作者:  Li, Chunpu;  Dai, Yang;  Kong, Xiangtai;  Wang, Bao;  Peng, Xia   |  收藏  |  浏览/下载：2/0  |  提交时间：2024/03/27