中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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  • 上海药物研究所 [216]
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Ent-labdane-type diterpene glycosides obtained from Rubus chingii Hu and their inhibitory effects on PDE5A activity 期刊论文  OAI收割
FITOTERAPIA, 2024, 卷号: 173, 页码: 14
作者:  
Yu, Jun-dong;  Wang, Jing-Yi;  Liu, Jia-yuan;  Xu, Ye-chun;  Zhang, Xue
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Discovery of hematopoietic progenitor kinase 1 inhibitors using machine learning-based screening and free energy perturbation 期刊论文  OAI收割
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2024, 页码: 13
作者:  
Feng, Dazhi;  Liu, Bo;  Chen, Zhiwei;  Xu, Jinyi;  Geng, Meiyu
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Discovery of JN122, a Spiroindoline-Containing Molecule that Inhibits MDM2/p53 Protein-Protein Interaction and Exerts Robust In Vivo Antitumor Efficacy 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 24, 页码: 16991-17025
作者:  
Cheng, Jing;  Yan, Ziqin;  Jiang, Kailong;  Liu, Chen;  Xu, Dehua
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A first-in-human phase 1 study of simnotrelvir, a 3CL-like protease inhibitor for treatment of COVID-19, in healthy adult subjects 期刊论文  OAI收割
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2023, 卷号: 191, 页码: 9
作者:  
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The claustrum-prelimbic cortex circuit through dynorphin/κ-opioid receptor signaling underlies depression-like behaviors associated with social stress etiology 期刊论文  OAI收割
NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 17
作者:  
Wang, Yu-Jun;  Zan, Gui-Ying;  Xu, Cenglin;  Li, Xue-Ping;  Shu, Xuelian
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An ultra-compact promoter drives widespread neuronal expression in mouse and monkey brains 期刊论文  OAI收割
CELL REPORTS, 2023, 卷号: 42, 期号: 11, 页码: 21
作者:  
Wang, Jingyi;  Lin, Jianbang;  Chen, Yefei;  Liu, Jing;  Zheng, Qiongping
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MiR-337-3p improves metabolic-associated fatty liver disease through regulation of metabolism 期刊论文  OAI收割
ISCIENCE, 2023, 卷号: 26, 期号: 11, 页码: 18
作者:  
Xu, Xiaoding;  Yu, Chuwei;  He, Hongxiu;  Pan, Xiangyu;  Hou, Aijun
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Discovery of a novel OGT inhibitor through high-throughput screening based on Homogeneous Time-Resolved Fluorescence (HTRF) 期刊论文  OAI收割
BIOORGANIC CHEMISTRY, 2023, 卷号: 139, 页码: 12
作者:  
Wu, Xinyu;  Wang, Mingchen;  Cao, Yu;  Xu, Ying;  Yang, Ziqun
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ETCM v2.0: An update with comprehensive resource and rich annotations for traditional Chinese medicine 期刊论文  OAI收割
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 6, 页码: 2559-2571
作者:  
Zhang, Yanqiong;  Li, Xin;  Shi, Yulong;  Chen, Tong;  Xu, Zhijian
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Stimuli-activatable PROTACs for precise protein degradation and cancer therapy 期刊论文  OAI收割
SCIENCE BULLETIN, 2023, 卷号: 68, 期号: 10, 页码: 1069-1085
作者:  
Gao, Jing;  Yang, Lei;  Lei, Shumin;  Zhou, Feng;  Nie, Huijun
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