机构

• 上海药物研究所 [36]

采集方式

• OAI收割 [36]

内容类型

• 期刊论文 [35]
• 会议论文 [1]

发表日期

• 2023 [4]
• 2022 [4]
• 2021 [6]
• 2020 [2]
• 2019 [2]
• 2018 [1]
• 更多

学科主题

筛选

浏览/检索结果: 共36条，第1-10条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Identification of [1,2,4]Triazolo[4,3-a]pyrazine PARP1 inhibitors with overcome acquired resistance activities 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 259, 页码: 19 作者:  Wang, Pingyuan;  Zhu, Wen-Ting;  Wang, Yajing;  Song, Shan-Shan;  Xi, Yong   |  收藏  |  浏览/下载：58/0  |  提交时间：2023/10/17 PARP1 inhibitor  Synthetic lethality  Drug resistance  Anticancer  Structure -activity relationship   Prime editing-based gene correction alleviates the hyperexcitable phenotype and seizures of a genetic epilepsy mouse model 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2023, 页码: 4 作者:  Cao, Bi-rong   |  收藏  |  浏览/下载：26/0  |  提交时间：2023/10/17 High-throughput screening of SARS-CoV-2 main and papain-like protease inhibitors 期刊论文  OAI收割 PROTEIN & CELL, 2023, 卷号: 14, 期号: 1, 页码: 17-27 作者:  Zang, Yi;  Su, Mingbo;  Wang, Qingxing;  Cheng, Xi;  Zhang, Wenru   |  收藏  |  浏览/下载：2/0  |  提交时间：2024/03/27 high-throughput screening  SARS  CoV-2  main  papain-like  proteases   Thioparib inhibits homologous recombination repair, activates the type I IFN response, and overcomes olaparib resistance 期刊论文  OAI收割 EMBO MOLECULAR MEDICINE, 2023, 页码: 24 作者:  Wang, Li-Min;  Wang, Pingyuan;  Chen, Xiao-Min   |  收藏  |  浏览/下载：21/0  |  提交时间：2023/04/10 homologous recombination repair  olaparib-resistant  PARP inhibitor  PARP7  type I interferons   Targeting UHRF1-SAP30-MXD4 axis for leukemia initiating cell eradication in myeloid leukemia 期刊论文  OAI收割 CELL RESEARCH, 2022, 页码: 19 作者:  Hu, Cheng-Long;  Chen, Bing-Yi;  Li, Zijuan;  Yang, Tianbiao;  Xu, Chun-Hui   |  收藏  |  浏览/下载：30/0  |  提交时间：2022/12/13 Synthesis of Hydantoin Androgen Receptor Antagonists and Study on Their Antagonistic Activity 期刊论文  OAI收割 MOLECULES, 2022, 卷号: 27, 期号: 18, 页码: 22 作者:  Ma, Longjun;  Zhou, Yan;  Yang, Dehua;  Wang, Ming-Wei;  Lu, Wei   |  收藏  |  浏览/下载：13/0  |  提交时间：2022/11/11 androgen receptor  antagonist  enzalutamide  hydantoin analogs  antiproliferative   Diversity-oriented synthesis of marine polybrominated diphenyl ethers as potential KCNQ potassium channel activators 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2022, 卷号: 126, 页码: 105909 作者:  Liu, Lai-Xin;  Gu, Ru-Rong;  Jin, Yang;  Chen, Xue-Qin;  Li, Xu-Wen   |  收藏  |  浏览/下载：7/0  |  提交时间：2024/03/21 Marine Natural product  Polybrominated diphenyl ethers  KCNQ potassium channel   Antidepressant-like effects of cinnamamide derivative M2 via D-2 receptors in the mouse medial prefrontal cortex 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2022, 页码: 9 作者:  Che, Yan-xin;  Jin, Xiao-yan;  Xiao, Rong-hua;  Zhang, Ming;  Ma, Xiao-hui   |  收藏  |  浏览/下载：17/0  |  提交时间：2022/06/15 depression  D-2 receptor  medial prefrontal cortex  pyramidal neurons  mTOR  TrkB   Synthesis and bioactivity studies of covalent inhibitors derived from (-)-Chaetominine 期刊论文  OAI收割 JOURNAL OF MOLECULAR STRUCTURE, 2021, 卷号: 1241, 页码: 14 作者:  Zhou, Xian;  Feng, Xuexin;  Wang, Dachi;  Chen, Deheng;  Wu, Gaoxing   |  收藏  |  浏览/下载：88/0  |  提交时间：2021/08/17 Chaetominine  Cellular growth inhibition  Cancer cell line  Covalent warhead   Structural insights into ligand recognition and activation of the melanocortin-4 receptor 期刊论文  OAI收割 CELL RESEARCH, 2021, 页码: 13 作者:  Zhang, Huibing;  Chen, Li-Nan;  Yang, Dehua;  Mao, Chunyou;  Shen, Qingya   |  收藏  |  浏览/下载：65/0  |  提交时间：2021/11/04