中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [10]
半导体研究所 [1]
上海硅酸盐研究所 [1]
采集方式
OAI收割 [12]
内容类型
期刊论文 [12]
发表日期
2019 [12]
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fDiscovery of pyrazole-thiophene derivatives as highly Potent, orally active Akt inhibitors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 180, 页码: 72-85
作者:
Zhan, Wenhu
;
Che, Jinxin
;
Xu, Lei
;
Wu, Yizhe
;
Hu, Xiaobei
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2020/07/01
Pyrazole-thiophene derivatives
Akt inhibitor
Antitumor
New linker structures applied in glycosite-specific antibody drug conjugates
期刊论文
OAI收割
ORGANIC CHEMISTRY FRONTIERS, 2019, 卷号: 6, 期号: 17, 页码: 3144-3149
作者:
Faridoon
;
Shi, Wei
;
Qin, Ken
;
Tang, Yubo
;
Li, Mingjie
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2020/07/01
Biofilm Nanofiber-Coated Separators for Dendrite-Free Lithium Metal Anode and Ultrahigh-Rate Lithium Batteries
期刊论文
OAI收割
ACS APPLIED MATERIALS & INTERFACES, 2019, 卷号: 11, 期号: 35, 页码: 32373
作者:
Nie, Lu
;
Li, Yingfeng
;
Chen, Shaojie
;
Li, Ke
;
Huang, Yuanqi
  |  
收藏
  |  
浏览/下载:78/0
  |  
提交时间:2019/12/26
biofilm nanofibers
separator
lithium dendrite
rate capability
high-voltage cathode
Selective Late-Stage Oxygenation of Sulfides with Ground-State Oxygen by Uranyl Photocatalysis
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2019, 页码: 9
作者:
Li, Yiming
;
Rizvi, S. Aal-e-Ali
;
Hu, Deqing
;
Sun, Danwen
;
Gao, Anhui
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2020/07/01
oxygen
oxygenation
photocatalysis
sulfides
uranyl catalysis
Discovery of 3,4,6-Trisubstituted Piperidine Derivatives as Orally Active, Low hERG Blocking Akt Inhibitors via Conformational Restriction and Structure-Based Design
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 15, 页码: 7264-7288
作者:
Dong, Xiaowu
;
Zhan, Wenhu
;
Zhao, Mengting
;
Che, Jinxin
;
Dai, Xiaoyang
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/07/01
Discovery of (R)-5-((5-(1-methyl-1H-pyrazol-4-yl)-4-(methylamino) pyrimidin-2-yl)amino)-3-(piperidin-3-yloxy)picolinonitrile, a novel CHK1 inhibitor for hematologic malignancies
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 173, 页码: 44-62
作者:
Tong, Lexian
;
Song, Pinrao
;
Jiang, Kailong
;
Xu, Lei
;
Jin, Tingting
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2020/07/01
CHK1 kinase inhibitor
Selectivity
Monotherapy
Hematologic malignancies
Tranylcypromine and 6-trifluoroethyl thienopyrimidine hybrid as LSD1 inhibitor
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2019, 卷号: 29, 期号: 6, 页码: 844-847
作者:
Wang, Xiaowen
;
Su, Mingbo
;
Li, You
;
Liu, Tongchao
;
Wang, Yujie
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2020/07/01
LSD1 inhibitor
Tranylcypromine
Menin-MLL1 protei n-protein interaction inhibitor
MV4-11 antiproliferative activity
Structure activity relationship
Discovery of novel indoleaminopyrimidine NIK inhibitors based on molecular docking-based support vector regression (SVR) model
期刊论文
OAI收割
CHEMICAL PHYSICS LETTERS, 2019, 卷号: 718, 页码: 38-45
作者:
Ye, Qing
;
Li, Qiu
;
Gao, Anhui
;
Ying, Huazhou
;
Cheng, Gang
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2020/07/01
Exploration of novel macrocyclic dipeptide N-benzyl amides as proteasome inhibitors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 164, 页码: 423-439
作者:
Yu, Jianjun
;
Liu, Jieyu
;
Li, Daqiang
;
Xu, Lei
;
Hong, Duidui
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2020/07/01
Proteasome inhibitors
Macrocyclic dipeptides
N-Benzyl amides
Metabolic stability
Synthesis and biological evaluation of 3-aryl-4-indolyl-maleimides as potent mutant isocitrate dehydrogenase-1 inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 4, 页码: 589-603
作者:
Liu, Xiaoqi
;
Hu, Yuanyuan
;
Gao, Anhui
;
Xu, Meng
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/07/01
3-Aryl-4-indolyl-maleimides
IDH1/R132H inhibitors
Tumor 2-HG
Synthesis