机构

• 上海药物研究所 [210]

采集方式

• OAI收割 [210]

内容类型

• 期刊论文 [209]
• 会议论文 [1]

发表日期

• 2024 [3]
• 2023 [12]
• 2022 [13]
• 2021 [18]
• 2020 [14]
• 2019 [11]
• 更多

学科主题

• Chemistry [3]
• Pharmacolo... [1]

筛选

浏览/检索结果: 共210条，第1-10条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Nanobodies as negative allosteric modulators for human calcium sensing receptor 期刊论文  OAI收割 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2024, 卷号: 695, 页码: 9 作者:  Cui, Qianqian;  Wang, Lu;  Wang, Haonan;  Chen, Xiaochen;  Han, Li   |  收藏  |  浏览/下载：16/0  |  提交时间：2024/04/09 G-protein-coupled receptor  Extracellular calcium sensing receptor  Nanobody  Cryo-electron microscope  Systemic Ca 2+homoeostasis   Pharmacologically significant constituents collectively responsible for anti-sepsis action of XueBiJing, a Chinese herb-based intravenous formulation 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2024, 页码: 16 作者:  Cheng, Chen;  Ren, Chao;  Li, Mu-zi;  Liu, Yi-hui;  Yao, Ren-qi   |  收藏  |  浏览/下载：11/0  |  提交时间：2024/02/27 Traditional Chinese medicine  XueBiJing  sepsis  mortality  pharmacokinetic compatibility  polypharmacology   A novel capsid-XL32-derived adeno-associated virus serotype prompts retinal tropism and ameliorates choroidal neovascularization 期刊论文  OAI收割 BIOMATERIALS, 2024, 卷号: 304, 页码: 13 作者:  Luo, Lin-Lin;  Xu, Jie;  Wang, Bing-Qiao;  Chen, Chen;  Chen, Xi   |  收藏  |  浏览/下载：9/0  |  提交时间：2024/01/26 AAV  Capsid engineering  Phosphosites mutation  Retinal tropism  Neovascularization   A first-in-human phase 1 study of simnotrelvir, a 3CL-like protease inhibitor for treatment of COVID-19, in healthy adult subjects 期刊论文  OAI收割 EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2023, 卷号: 191, 页码: 9 作者:  Yang, Xin-Mei;  Yang, Yang;  Yao, Bu-Fan;  Ye, Pan-Pan   |  收藏  |  浏览/下载：11/0  |  提交时间：2023/12/11 COVID-19  Simnotrelvir  Safety  Pharmacokinetics  Healthy subjects   AMPK role in epilepsy: a promising therapeutic target? 期刊论文  OAI收割 JOURNAL OF NEUROLOGY, 2023, 页码: 24 作者:  Qi, Yingbei;  Zhang, Yong-mei;  Gao, Ya-nan;  Chen, Wen-gang;  Zhou, Ting   |  收藏  |  浏览/下载：7/0  |  提交时间：2024/01/26 AMPK  Epilepsy  Neuron Modulation  Metabolism  Ion Channels  mTOR   HDAC3 and HDAC8 PROTAC dual degrader reveals roles of histone acetylation in gene regulation 期刊论文  OAI收割 CELL CHEMICAL BIOLOGY, 2023, 卷号: 30, 期号: 11, 页码: 1421-+ 作者:  Xiao, Yufeng;  Hale, Seth;  Awasthee, Nikee;  Meng, Chengcheng;  Zhang, Xuan   |  收藏  |  浏览/下载：10/0  |  提交时间：2024/01/16 Asponchimides A-E: new enantiomeric N-acetyldopamine trimers from Aspongopus chinensis 期刊论文  OAI收割 CHINESE JOURNAL OF NATURAL MEDICINES, 2023, 卷号: 21, 期号: 11, 页码: 859-867 作者:  Nie, Jinchun;  Mei, Fang;  Zheng, Yueyuan;  Wen, Qiuyi;  Li, Zhenwei   |  收藏  |  浏览/下载：7/0  |  提交时间：2024/01/26 Aspongopus chinensis  N-acetyldopamine trimer  ECD calculations  NO inhibitory activity   Anxiolytic effect of antidiabetic metformin is mediated by AMPK activation in mPFC inhibitory neurons 期刊论文  OAI收割 MOLECULAR PSYCHIATRY, 2023, 页码: 11 作者:  Zhang, Yong-mei;  Zong, Hai-chao;  Qi, Ying-bei;  Chang, Liu-liu;  Gao, Ya-nan   |  收藏  |  浏览/下载：10/0  |  提交时间：2023/12/08 The Cocrystal of Ubiquinol: Improved Stability and Bioavailability 期刊论文  OAI收割 PHARMACEUTICS, 2023, 卷号: 15, 期号: 10, 页码: 12 作者:  Zhang, Qi;  Xia, Mengyuan;  Zheng, Chenxuan;  Yang, Yinghong;  Bao, Junjie   |  收藏  |  浏览/下载：8/0  |  提交时间：2023/12/11 ubiquinol  cocrystal  polymorph  stability  bioavailability   Discovery, structural optimization, and anti-tumor bioactivity evaluations of betulinic acid derivatives as a new type of ROR & gamma; antagonists 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 257, 页码: 15 作者:  Mei, Lianghe;  Xu, Lansong;  Wu, Sanan;  Wang, Yafang;  Xu, Chao   |  收藏  |  浏览/下载：39/0  |  提交时间：2023/10/17 Betulinic acid  ROR & gamma  Target identification  Rationale structure optimization  Anti-tumor effects  antagonists