中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [33]
采集方式
OAI收割 [33]
内容类型
期刊论文 [32]
会议论文 [1]
发表日期
2023 [6]
2022 [2]
2021 [2]
2020 [2]
2018 [3]
2017 [3]
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浏览/检索结果:
共33条,第1-10条
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专题:上海药物研究所
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A first-in-human phase 1 study of simnotrelvir, a 3CL-like protease inhibitor for treatment of COVID-19, in healthy adult subjects
期刊论文
OAI收割
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2023, 卷号: 191, 页码: 9
作者:
Yang, Xin-Mei
;
Yang, Yang
;
Yao, Bu-Fan
;
Ye, Pan-Pan
;
Xu, Yan
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/12/11
COVID-19
Simnotrelvir
Safety
Pharmacokinetics
Healthy subjects
HDAC3 and HDAC8 PROTAC dual degrader reveals roles of histone acetylation in gene regulation
期刊论文
OAI收割
CELL CHEMICAL BIOLOGY, 2023, 卷号: 30, 期号: 11, 页码: 1421-+
作者:
Xiao, Yufeng
;
Hale, Seth
;
Awasthee, Nikee
;
Meng, Chengcheng
;
Zhang, Xuan
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/01/16
Asponchimides A-E: new enantiomeric N-acetyldopamine trimers from Aspongopus chinensis
期刊论文
OAI收割
CHINESE JOURNAL OF NATURAL MEDICINES, 2023, 卷号: 21, 期号: 11, 页码: 859-867
作者:
Nie, Jinchun
;
Mei, Fang
;
Zheng, Yueyuan
;
Wen, Qiuyi
;
Li, Zhenwei
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/01/26
Aspongopus chinensis
N-acetyldopamine trimer
ECD calculations
NO inhibitory activity
Multiple heart-cutting two-dimensional liquid chromatography/charged aerosol detector assay of ginsenosides for quality evaluation of ginseng from diverse Chinese patent medicines
期刊论文
OAI收割
JOURNAL OF CHROMATOGRAPHY A, 2023, 卷号: 1708, 页码: 10
作者:
Xu, Xiao-yan
;
Jiang, Mei-ting
;
Wang, Yu
;
Sun, He
;
Jing, Qi
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/12/08
Multiple heart -cutting two-dimensional liquid
chromatography
Charged aerosol detector
Quantitative assay
Ginseng
Chinese patent medicine
The Cocrystal of Ubiquinol: Improved Stability and Bioavailability
期刊论文
OAI收割
PHARMACEUTICS, 2023, 卷号: 15, 期号: 10, 页码: 12
作者:
Zhang, Qi
;
Xia, Mengyuan
;
Zheng, Chenxuan
;
Yang, Yinghong
;
Bao, Junjie
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/12/11
ubiquinol
cocrystal
polymorph
stability
bioavailability
Comparative Characterization of the Ginsenosides from Six Panax Herbal Extracts and Their In Vitro Rat Gut Microbial Metabolites by Advanced Liquid Chromatography-Mass Spectrometry Approaches
期刊论文
OAI收割
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2023, 卷号: 71, 期号: 24, 页码: 9391-9403
作者:
Mi, Yue-Guang
;
Xu, Xiao-Yan
;
Hong, Li-Li
;
Jiang, Mei-Ting
;
Chen, Bo-Xue
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/10/17
Panax
multicomponent characterization
quantitative assay
gut microbiota
in vitro biotransformation
liquid chromatography-massspectrometry
Absorption, distribution, metabolism, and excretion of [C-14]Mefuparib (CVL218), a novel PARP1/2 inhibitor, in rats
期刊论文
OAI收割
CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2022, 页码: 12
作者:
Li, Xin-mei
;
Zheng, Yuan-dong
;
Zhang, Yi-fan
;
Huan, Xia-juan
;
Yang, Chen
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2022/12/13
[C-14]Mefuparib
Mefuparib (CVL218)
Blood-brain barrier
Mass balance
Tissue distribution
GastroPlus simulation
Deciphering COVID-19 host transcriptomic complexity and variations for therapeutic discovery against new variants
期刊论文
OAI收割
ISCIENCE, 2022, 卷号: 25, 期号: 10, 页码: 28
作者:
Xing, Jing
;
Shankar, Rama
;
Ko, Meehyun
;
Zhang, Keke
;
Zhang, Sulin
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2022/11/11
Survival-Assured Liver Injury Preconditioning (SALIC) Enables Robust Expansion of Human Hepatocytes in Fah(-/-)Rag2(-/-)IL2rg(-/-) Rats
期刊论文
OAI收割
ADVANCED SCIENCE, 2021, 页码: 14
作者:
Zhang, Ludi
;
Ge, Jian-Yun
;
Zheng, Yun-Wen
;
Sun, Zhen
;
Wang, Chenhua
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2021/11/04
bioreactor
humanized liver
liver xeno-repopulation
pharmacological study
Comprehensive evaluation of NAODESHENG by combining UPLC quantitative fingerprint and antioxidant activity
期刊论文
OAI收割
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2021, 卷号: 193, 页码: 7
作者:
Liao, Jun-cheng
;
Wu, Yun-shan
;
Xu, Fang-fang
;
Chen, Wei-ying
;
Zheng, Zuo-liang
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2021/05/24
Determination of content
NAODESHENG
Multi-wavelength fusion fingerprint
Anti-oxidation
Traditional Chinese Medicine (TCM)