中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [19]
昆明动物研究所 [9]
长春应用化学研究所 [3]
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OAI收割 [35]
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期刊论文 [35]
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Bioactive Effects of Curcumin in Human Immunodeficiency Virus Infection Along with the Most Effective Isolation Techniques and Type of Nanoformulations
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF NANOMEDICINE, 2022, 卷号: 17, 期号: 0, 页码: 3619-3632
作者:
Butnariu, Monica
;
Quispe, Cristina
;
Koirala, Niranjan
;
Khadka, Sujan
;
Salgado-Castillo, Carla Marina
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2022/11/09
MICROWAVE-ASSISTED EXTRACTION
ANTIRETROVIRAL THERAPY
BIOLOGICAL-ACTIVITIES
HIV-1 INTEGRASE
BREAST-CANCER
UP-REGULATION
NANOPARTICLES
DERIVATIVES
MECHANISMS
INHIBITION
Discovery of novel 3-hydroxypicolinamides as selective inhibitors of HIV-1 integrase-LEDGF/p75 interaction
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 125, 页码: 1051-1063
作者:
Zhang, Feng-Hua
;
Debnath, Bikash
;
Xu, Zhong-Liang
;
Yang, Liu-Meng
;
Song, Li-Rui
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/01/08
HIV-1 integrase
Allosteric inhibitor
LEDGF/p75
Dimerization
3-Hydroxypicolinamide
Discovery of novel 3-hydroxypicolinamides as selective inhibitors of HIV-1 integrase-LEDGF/p75 interaction
期刊论文
OAI收割
European Journal of Medicinal Chemistry, 2017, 卷号: 125, 期号: X, 页码: 1051-1063
作者:
Zhang FH
;
Debnath B
;
Zheng YT
;
Neamati N[*]
;
Long YQ[*]
收藏
  |  
浏览/下载:72/0
  |  
提交时间:2016/11/07
3-Hydroxypicolinamide
Allosteric inhibitor
Dimerization
HIV-1 integrase
LEDGF/p75
Synthesis and Anti-HIV-1 Activity Evaluation for Novel 3a,6a-Dihydro-1H-pyrrolo[3,4-c]pyrazole-4,6-dione Derivatives
期刊论文
OAI收割
MOLECULES, 2016, 卷号: 21, 期号: 9
作者:
Liu, Guan-Nan
;
Luo, Rong-Hua
;
Zhou, Yu
;
Zhang, Xing-Jie
;
Li, Jian
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/01/08
anti-HIV-1
integrase
synthesis
SAR
AIDS
Synthesis and Anti-HIV-1 Activity Evaluation for Novel 3a,6a-Dihydro-1H-pyrrolo[3,4-c]pyrazole-4,6-dione Derivatives
期刊论文
OAI收割
Molecules, 2016, 卷号: 21, 期号: 9, 页码: e1198
作者:
Liu GN
;
Luo RH
;
Yang LM
;
Zheng YT[*]
;
Liu H[*]
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2016/09/18
AIDS
SAR
anti-HIV-1
integrase
synthesis
Design and discovery of flavonoid-based HIV-1 integrase inhibitors targeting both the active site and the interaction with LEDGF/p75
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2014, 卷号: 22, 期号: 12, 页码: 3146-3158
作者:
Li, Bo-Wen
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/01/08
HIV-1 integrase inhibitors
Flavonoid
Chelation
Strand transfer
LEDGF/p75
Discovery of a novel HIV-1 integrase inhibitor from natural compounds through structure based virtual screening and cell imaging
期刊论文
OAI收割
FEBS LETTERS, 2014, 卷号: 588, 期号: 18, 页码: 3461-3468
作者:
Gu WG
;
Zhang X
;
Ip DTM
;
Yang LM
;
Zheng YT
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2014/10/10
HIV-1 integrase
Lens epithelium-derived growth factor (LEDGF/P75)
Virtual screening
Design and discovery of flavonoid-based HIV-1 integrase inhibitors targeting both the active site and the interaction with LEDGF/p75
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2014, 卷号: 22, 期号: 12, 页码: 3146-3158
作者:
Li BW
;
Zhang FH
;
Serrao E
;
Chen H
;
Sanchez TW
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2014/10/15
Chelation
Strand transfer
LEDGF/p75
HIV-1 integrase inhibitors
Flavonoid
1,4-Bis(5-(naphthalen-1-yl)thiophen-2-yl)naphthalene, a small molecule, functions as a novel anti-HIV-1 inhibitor targeting the interaction between integrase and cellular Lens epithelium-derived growth factor
期刊论文
OAI收割
CHEMICO-BIOLOGICAL INTERACTIONS, 2014, 卷号: 213, 期号: X, 页码: 21-27
作者:
Gu WG
;
Ip DTM
;
Liu SJ
;
Chan JH
;
Wang Y
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2014/10/15
HIV-1 integrase
Lens epithelium-derived growth factor (LEDGF/P75
Molecular docking
2芳基3羰基喹诺酮新型hcvns5b多聚酶抑制剂的设计合成和活性评估
期刊论文
OAI收割
化学学报, 2014, 卷号: 72, 期号: 8, 页码: 906
作者:
王沈丰
;
林建平
;
何佩岚
;
左建平
;
龙亚秋
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2020/07/01
HEPATITIS-C VIRUS
HIV-1 INTEGRASE INHIBITORS
INFECTION
NUCLEOTIDE
SCAFFOLD
SOFOSBUVIR
DISCOVERY
LEDGF/P75
ACIDS
HCV NS5B polymerase
2-substituted quinolone-3-carboxylic acid
non-nucleoside inhibitor
direct acting antiviral
allosteric site