机构

• 上海药物研究所 [12]
• 金属研究所 [2]
• 青海盐湖研究所 [2]
• 广州生物医药与健康研... [2]
• 物理研究所 [1]
• 中国科学院大学 [1]
• 更多

采集方式

• OAI收割 [22]
• iSwitch采集 [2]

内容类型

• 期刊论文 [24]

发表日期

• 2022 [4]
• 2021 [2]
• 2020 [6]
• 2019 [3]
• 2018 [2]
• 2016 [1]
• 更多

学科主题

• Chemistry [2]

筛选

浏览/检索结果: 共24条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Structure-based rational design enables efficient discovery of a new selective and potent AKT PROTAC degrader 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 238, 页码: 15 作者:  Zhu, Cheng-Liang;  Luo, Xiaomin;  Tian, Tian;  Rao, Zijian;  Wang, Hanlin   |  收藏  |  浏览/下载：28/0  |  提交时间：2022/08/16 AKT  Protein kinase B  PROTAC  Chemical degrader  Rational design   Structural Feature Analyzation Strategies toward Discovery of Orally Bioavailable PROTACs of Bruton's Tyrosine Kinase for the Treatment of Lymphoma 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 13, 页码: 9096–9125 作者:  Zhang, Jingyu;  Che, Jinxin;  Luo, Xiaomin;  Wu, Mingfei;  Kan, Weijuan   |  收藏  |  浏览/下载：16/0  |  提交时间：2024/03/21 Design, synthesis and biological evaluation of sulfonamides inhibitors of XPO1 displaying activity against multiple myeloma cells 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 235 作者:  Qu, Bingxue;  Xu, Yongjin;  Lu, Yang;  Zhuang, Weihao;  Jin, Xinxin   |  收藏  |  浏览/下载：24/0  |  提交时间：2022/12/23 XPO1  Multiple myeloma  MM.1S  N-phenylsulfonamide  Oral administration   Discovery of seneciobipyrrolidine derivatives for the amelioration of glucose homeostasis disorders through 4E-BP1/Akt/AMPK signaling activation 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 228, 页码: 25 作者:  Che, Jinxin;  Ma, Canliang;  Lu, Jialiang;  Chen, Binhui;  Shi, Qiuqiu   |  收藏  |  浏览/下载：30/0  |  提交时间：2022/06/15 Seneciobipyrrolidine  Phenotypic screening  Glucose homeostasis  Proteomic analysis  L6 myotubes  4E-BP1   Advancing COVID-19 diagnosis with privacy-preserving collaboration in artificial intelligence 期刊论文  OAI收割 NATURE MACHINE INTELLIGENCE, 2021, 卷号: 3, 期号: 12, 页码: 1081-1089 作者:  Bai, Xiangd;  Wang, Hanchen;  Ma, Liya;  Xu, Yongchao;  Gan, Jiefeng   |  收藏  |  浏览/下载：63/0  |  提交时间：2022/01/18 Recovery of Co, Ni, and Li from solutions by solvent extraction with beta-diketone system 期刊论文  OAI收割 HYDROMETALLURGY, 2021, 卷号: 204 作者:  Zhang, Licheng;  Ji, Lianmin;  Li, Lijuan;  Shi, Dong;  Xu, Taoshan   |  收藏  |  浏览/下载：22/0  |  提交时间：2022/03/28 Structure-based design, synthesis and bioactivity evaluation of macrocyclic inhibitors of mutant isocitrate dehydrogenase 2 (IDH2) displaying activity in acute myeloid leukemia cells 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 203, 页码: 19 作者:  Che, Jinxin;  Huang, Feng;  Zhang, Mengmeng;  Xu, Gaoya;  Qu, Bingxue   |  收藏  |  浏览/下载：41/0  |  提交时间：2020/12/21 Metabolic pathways  Isocitrate dehydrogenase 2  Conformational restriction  Macrocyclic derivatives  Inhibitors   Structure-based design, synthesis and bioactivity evaluation of macrocyclic inhibitors of mutant isocitrate dehydrogenase 2 (IDH2) displaying activity in acute myeloid leukemia cells 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 203, 页码: 19 作者:  Che, Jinxin;  Huang, Feng;  Zhang, Mengmeng;  Xu, Gaoya;  Qu, Bingxue   |  收藏  |  浏览/下载：26/0  |  提交时间：2020/12/21 Metabolic pathways  Isocitrate dehydrogenase 2  Conformational restriction  Macrocyclic derivatives  Inhibitors   Novel injectable and self-setting composite materials for bone defect repair 期刊论文  OAI收割 SCIENCE CHINA-MATERIALS, 2020, 卷号: 63, 期号: 5, 页码: 876-887 作者:  Xu, Qian;  Liang, Jiulong;  Xue, Haipeng;  Liu, Yun'en;  Cao, Lei   |  收藏  |  浏览/下载：8/0  |  提交时间：2021/02/02 nanoparticles  magnesium substitution  injectable materials  self-setting  bone defect repair   Novel injectable and self-setting composite materials for bone defect repair 期刊论文  OAI收割 SCIENCE CHINA-MATERIALS, 2020, 卷号: 63, 期号: 5, 页码: 876-887 作者:  Xu, Qian;  Liang, Jiulong;  Xue, Haipeng;  Liu, Yun'en;  Cao, Lei   |  收藏  |  浏览/下载：16/0  |  提交时间：2021/02/02 nanoparticles  magnesium substitution  injectable materials  self-setting  bone defect repair