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Chinese Academy of Sciences Institutional Repositories Grid
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  • 2018 [59]
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Discovery of new potent protein arginine methyltransferase 5 (PRMT5) inhibitors by assembly of key pharmacophores from known inhibitors 期刊论文  OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 23-24, 页码: 3693-3699
作者:  Zhu, Kongkai;  Song, Jia-Li;  Tao, Hong-Rui;  Cheng, Zhi-Qiang;  Jiang, Cheng-Shi
  |  收藏  |  浏览/下载：100/0  |  提交时间：2019/01/08
Discovery of novel antagonists on (2)-adrenoceptor from natural products using a label-free cell phenotypic assay 期刊论文  OAI收割
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 2018, 卷号: 391, 期号: 12, 页码: 1411-1420
作者:  Wang, Anhui;  Zhang, Pengyu;  Wang, Jixia;  Zhao, Ying;  Zhang, Xiuli
  |  收藏  |  浏览/下载：55/0  |  提交时间：2019/06/20
Identification of 5-benzylidene-2-phenylthiazolones as potent PRMT5 inhibitors by virtual screening, structural optimization and biological evaluations 期刊论文  OAI收割
BIOORGANIC CHEMISTRY, 2018, 卷号: 81, 页码: 289-298
作者:  Zhu, Kongkai;  Tao, Hongrui;  Song, Jia-Li;  Jin, Lu;  Zhang, Yuanyuan
  |  收藏  |  浏览/下载：129/0  |  提交时间：2019/01/08
Q63, a novel DENV2 RdRp non-nucleoside inhibitor, inhibited DENV2 replication and infection 期刊论文  OAI收割
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2018, 卷号: 138, 期号: 4, 页码: 247-256
作者:  Yao, Xingang;  Guo, Songxin;  Wu, Wenyu;  Wang, Jinan;  Wu, Shengen
  |  收藏  |  浏览/下载：100/0  |  提交时间：2019/01/08
Bioactive polycyclic polyprenylated acylphloroglucinols from Hypericum perforatum 期刊论文  OAI收割
ORGANIC & BIOMOLECULAR CHEMISTRY, 2018, 卷号: 16, 期号: 43, 页码: 8130-8143
作者:  Guo, Yi;  Zhang, Na;  Sun, Weiguang;  Duan, Xueyan;  Zhang, Qing
  |  收藏  |  浏览/下载：92/0  |  提交时间：2018/12/18
Design, Synthesis, and SAR Studies of Heteroarylpyrimidines and Heteroaryltriazines as CB2R Ligands 期刊论文  OAI收割
CHEMMEDCHEM, 2018, 卷号: 13, 期号: 22, 页码: 2455-2463
作者:  Qian, Hai-Yan;  Wang, Zhi-Long;  Chen, Li-Li;  Pan, You-Lu;  Xie, Xiao-Yu
  |  收藏  |  浏览/下载：90/0  |  提交时间：2019/01/08
Mechanistic Insights into Interactions between Bacterial Class I P450 Enzymes and Redox Partners 期刊论文  OAI收割
ACS CATALYSIS, 2018, 卷号: 8, 期号: 11, 页码: 9992-10003
作者:  Zhang, Wei;  Du, Lei;  Li, Fengwei;  Zhang, Xingwang;  Qu, Zepeng
  |  收藏  |  浏览/下载：142/0  |  提交时间：2018/12/21
Pharmacophore modeling, molecular docking and molecular dynamics simulations toward identifying lead compounds for Chk1 期刊论文  OAI收割
COMPUTATIONAL BIOLOGY AND CHEMISTRY, 2018, 卷号: 76, 页码: 53-60
作者:  Li, Yaping;  Peng, Jiale;  Zhou, Yeheng;  Li, Penghua;  Li, Yingying
  |  收藏  |  浏览/下载：29/0  |  提交时间：2018/11/12
Artificial intelligence in drug design 期刊论文  OAI收割
SCIENCE CHINA-LIFE SCIENCES, 2018, 卷号: 61, 期号: 10, 页码: 1191-1204
作者:  Zhong, Feisheng;  Xing, Jing;  Li, Xutong;  Liu, Xiaohong;  Fu, Zunyun
  |  收藏  |  浏览/下载：28/0  |  提交时间：2019/01/08
Synthesis and In Vitro Antitumor Activity of Novel Bivalent -Carboline-3-carboxylic Acid Derivatives with DNA as a Potential Target 期刊论文  OAI收割
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2018, 卷号: 19, 期号: 10
作者:  Gu, Hongling
  |  收藏  |  浏览/下载：30/0  |  提交时间：2019/01/08