中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [36]
采集方式
OAI收割 [36]
内容类型
期刊论文 [36]
发表日期
2024 [2]
2023 [4]
2021 [4]
2020 [2]
2019 [1]
2018 [1]
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浏览/检索结果:
共36条,第1-10条
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存缴方式:oaiharvest
专题:上海药物研究所
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Gold-catalyzed
endo
-selective Ring-opening of Epoxides and its Application in Construction of Poly-ethers
期刊论文
OAI收割
CHEMISTRY-A EUROPEAN JOURNAL, 2024, 页码: 10
作者:
Wu, Kehuan
;
Kang, Kaiwen
;
Liu, Dan
;
Zhang, Chiyue
;
Wang, Xinyu
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/03/25
6-endo ring-opening of epoxide
Baldwin's rules
gold-catalyzed reactions
marine ladder-like poly-ethers
Nakanishi hypothesis
Novel imidazo[1,2,4] triazole derivatives: Synthesis, fluorescence, bioactivity for SHP1
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 265, 页码: 15
作者:
Yan, Xue
;
Zhang, Chun
;
Gao, Li-Xin
;
Liu, Min -Min
;
Yang, Yu-Ting
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/02/27
Imidazo[124] triazole derivatives
Fluorescence property
SHP1
Bioactivity
Cellular imaging
Gut Microbiota Metabolite 3-Indolepropionic Acid Directly Activates Hepatic Stellate Cells by ROS/JNK/p38 Signaling Pathways
期刊论文
OAI收割
BIOMOLECULES, 2023, 卷号: 13, 期号: 10, 页码: 14
作者:
Yuan, Xiaoyan
;
Yang, Junting
;
Huang, Yuling
;
Li, Jia
;
Li, Yuanyuan
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2023/12/08
gut-liver axis
3-Indolepropionic acid
HSCs
liver fibrosis
Construction of Diversified Penta-Spiro-Heterocyclic and Fused-Heterocyclic Frameworks with Potent Antitumor Activity
期刊论文
OAI收割
CHEMISTRY-A EUROPEAN JOURNAL, 2023, 页码: 7
作者:
Liu, Qi
;
Liu, Xuyi
;
Li, Yazhou
;
Zhou, Yu
;
Zhao, Linxiang
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2023/10/17
spiro
fused-heterocyclic frameworks
substrate- and pH- controlled strategies
C-H activation
[4+1] and [4+2] annulation
antitumor
indazolone
Asymmetric C1 Extension of Aldehydes through Biocatalytic Cascades for Stereodivergent Synthesis of Mandelic Acids
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2023, 卷号: 62, 期号: 20
作者:
Liu, Yanqiong
;
Fu, Zunyun
;
Dong, Haihong
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2024/03/27
Asymmetric C-1 Extension
Biocatalysis
Biocatalytic Cascades
(S)-4-Hydroxymandelate Synthase
Mandelic Acids
Rh(III)-Catalyzed Successive C-H Activations of 2-Phenyl-3H-indoles and Cyclization Cascades to Construct Highly Fused Indole Heteropolycycles
期刊论文
OAI收割
ORGANIC LETTERS, 2023, 页码: 6
作者:
Gao, Ju
;
Luo, Keyu
;
Wei, Xiaohui
;
Wang, Hao
;
Liu, Hong
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2023/10/17
Theoretical study and application of 2-phenyl-1,3,4-thiadiazole derivatives with optical and inhibitory activity against SHP1
期刊论文
OAI收割
PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 2021, 页码: 14
作者:
Zhang, Chun
;
Sun, Yi-Tao
;
Gao, Li-Xin
;
Feng, Bo
;
Yan, Xue
  |  
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2022/01/18
Synthesis and biological evaluation of 2,5-diaryl-1,3,4-oxadiazole derivatives as novel Src homology 2 domain-containing protein tyrosine phosphatase 2 (SHP2) inhibitors
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2021, 卷号: 116, 页码: 13
作者:
Meng, Xiang-Dong
;
Gao, Li-Xin
;
Wang, Zhi-Jia
  |  
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2021/12/01
2,5-diphenyl-1,3,4-oxadiazole derivatives
SHP2
Inhibitors
Structure-activity relationships (SAR)
Synthesis of 5-Phenyl-1,3,4-thiadiazole Derivatives and Their Biochemical Evaluation against Src Homology 2 Domain-Containing Protein Tyrosine Phosphatase 1 (SHP1)
期刊论文
OAI收割
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2021, 卷号: 41, 期号: 8, 页码: 3097-3105
作者:
Yu Lijie
;
Feng Bo
;
Wang Zhijia
;
Gao Lixin
;
Zhang Chun
  |  
收藏
  |  
浏览/下载:95/0
  |  
提交时间:2021/11/04
5-phenyl-1,3,4-thiadiazole derivatives
Src homology 2 domain-containing protein tyrosine phosphatase 1 (SHP1)
inhibitors
structure-activity relationships
Discovery of thalidomide-based PROTAC small molecules as the highly efficient SHP2 degraders
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 218, 页码: 14
作者:
Yang, Xiangbo
;
Wang, Zhijia
;
Pei, Yuan
;
Song, Ning
;
Xu, Lei
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2021/08/17
SHP2 degradation
Proteolysis targeting chimera (PROTAC)
Thalidomide-based heterobifunctional molecules
E3 ubiquitin ligase
CRBN