中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
首页
机构
成果
学者
登录
注册
登陆
×
验证码:
换一张
忘记密码?
记住我
×
校外用户登录
CAS IR Grid
机构
上海药物研究所 [17]
采集方式
OAI收割 [17]
内容类型
期刊论文 [17]
发表日期
2022 [17]
学科主题
筛选
浏览/检索结果:
共17条,第1-10条
帮助
限定条件
存缴方式:oaiharvest
发表日期:2022
专题:上海药物研究所
第一署名单位
第一作者单位
通讯作者单位
条数/页:
5
10
15
20
25
30
35
40
45
50
55
60
65
70
75
80
85
90
95
100
排序方式:
请选择
提交时间升序
提交时间降序
题名升序
题名降序
作者升序
作者降序
发表日期升序
发表日期降序
Changes in Disposition of Ezetimibe and Its Active Metabolites Induced by Impaired Hepatic Function: The Influence of Enzyme and Transporter Activities
期刊论文
OAI收割
PHARMACEUTICS, 2022, 卷号: 14, 期号: 12, 页码: 22
作者:
Xie, Ningjie
;
Wang, Hong
;
Qin, Hua
;
Guo, Zitao
;
Xue, Hao
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2023/04/10
hepatic impairment
ezetimibe
active metabolites
phase II enzymes
transporters
first-pass metabolism
inhibitory bile acids
Neuroprotective effects of a lead compound from coral via modulation of the orphan nuclear receptor Nurr1
期刊论文
OAI收割
CNS NEUROSCIENCE & THERAPEUTICS, 2022, 页码: 14
作者:
Su, Jian-Wei
;
Yang, Pei
;
Xing, Mei-Mei
;
Chen, Bao
;
Xie, Xia-Hong
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2023/04/10
C
elegans
corals-derived compounds
neuroprotection
Nurr1
SH-SY5Y cells
Integration of offline two-dimensional chromatography and mass defect filtering-based precursor ion list data acquisition for targeted characterization of diterpenoid alkaloids in the lateral roots of Aconitum carmichaelii
期刊论文
OAI收割
JOURNAL OF CHROMATOGRAPHY A, 2022, 卷号: 1684, 页码: 12
作者:
Yu, Yang
;
Yao, Changliang
;
Wei, Wenlong
;
Li, Haojv
;
Huang, Yong
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2022/12/13
Offline two-dimensional chromatography
Mass defect filtering
Precursor ion list
Diterpenoid alkaloids
Aconitum carmichaelii
Mass spectrometry imaging: new eyes on natural products for drug research and development
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 页码: 16
作者:
Hou, Jin-jun
;
Zhang, Zi-jia
;
Wu, Wen-yong
;
He, Qing-qing
;
Zhang, Teng-qian
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2022/11/11
natural product
mass spectrometry imaging
MALDI
DESI
molecular imaging
ion mobility
Discovery and characterization of a novel cGAS covalent inhibitor for the treatment of inflammatory bowel disease
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 页码: 10
作者:
Song, Jia
;
Yang, Rui-rui
;
Chang, Jie
;
Liu, Ya-dan
;
Lu, Cheng-hao
  |  
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2022/11/11
cyclic GMP-AMP synthase
covalent inhibitor
inflammatory bowel disease
high-throughput screening
Design, synthesis and in vitro biological evaluation of marine phidianidine derivatives as potential anti-inflammatory agents
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2022, 卷号: 71, 页码: 116936
作者:
Xu, Quan
;
Zhao, Ning
;
Liu, Jin
;
Song, Jin-Qian
;
Huang, Li-Hua
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2024/03/21
Indole alkaloids
Marine natural products
Phidianidines
Anti-inflammatory activities
Molecular docking
Determination of six core components from Mahuang Xuanfei Zhike syrup in rat plasma and tissues by UPLC-MS/MS: Application to a pharmacokinetics and tissue distribution study
期刊论文
OAI收割
BIOMEDICAL CHROMATOGRAPHY, 2022, 页码: 15
作者:
Yang, Yang
;
Zhu, Jing
;
Yao, Chang-liang
;
Guo, De-an
;
He, Na
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2022/11/11
Mahuang Xuanfei Zhike syrup
pharmacokinetics
tissue distribution
UPLC-MS
MS
Development of a variant of dinutuximab with enhanced antitumor efficacy and reduced induction of neuropathic pain
期刊论文
OAI收割
FEBS OPEN BIO, 2022, 卷号: 12, 期号: 9, 页码: 1644-1656
作者:
Liu, Xin-Yuan
;
Chen, Yi-Li
;
Liu, Guo-Jian
;
Deng, Xiang-Nan
;
Cui, Yue
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2022/09/30
ADCC
affinity maturation
antibody engineering
anti-GD2 antibodies
engineered Fc domain
humanized
BPTF inhibition antagonizes colorectal cancer progression by transcriptionally inactivating Cdc25A
期刊论文
OAI收割
REDOX BIOLOGY, 2022, 卷号: 55, 页码: 16
作者:
Guo, Ping
;
Zu, Shijia
;
Han, Shilong
;
Yu, Wendan
;
Xue, Guoqing
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2022/12/13
Colorectal cancer
BPTF
Cdc25A
c-Myc
Cell cycle
Loss of SIRT5 promotes bile acid-induced immunosuppressive microenvironment and hepatocarcinogenesis
期刊论文
OAI收割
JOURNAL OF HEPATOLOGY, 2022, 卷号: 77, 期号: 2, 页码: 453-466
作者:
Sun, Renqiang
;
Zhang, Zhiyong
;
Bao, Ruoxuan
;
Guo, Xiaozhen
;
Gu, Yuan
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2024/03/21
SIRT5
bile acid
macrophage polarization
immunosuppressive tumor microenvironment
liver cancer