中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [64]
采集方式
OAI收割 [64]
内容类型
期刊论文 [64]
发表日期
2022 [64]
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共64条,第1-10条
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存缴方式:oaiharvest
发表日期:2022
专题:上海药物研究所
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Hiding Payload Inside the IgG Fc Cavity Significantly Enhances the Therapeutic Index of Antibody-Drug Conjugates
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 页码: 16
作者:
Shi, Wei
;
Zhang, Jianxin
;
Liu, Liya
;
Li, Wanzhen
;
Liu, Zhi
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2023/04/10
Molecular recognition of two endogenous hormones by the human parathyroid hormone receptor-1
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 页码: 11
作者:
Zhao, Li-hua
;
Yuan, Qing-ning
;
Dai, An-tao
;
He, Xin-heng
;
Chen, Chuan-wei
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2023/04/10
G protein- coupled receptors
parathyroid hormone
PTH-related peptide
PTH receptor-1
cryo-electron microscopy structure
osteoporosis
New flexible cembrane-type macrocyclic diterpenes as TNF-α inhibitors from the South China Sea soft coral Sarcophyton mililatensis
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2022, 卷号: 222, 页码: 880-886
作者:
Bu, Qing
;
Yang, Min
;
Yan, Xian-Yun
;
Yao, Li-Gong
;
Guo, Yue-Wei
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2024/03/21
Sarcophyton mililatensis
Cembrane
Macrocyclic diterpene
Absolute configuration
TNF
? inhibitor
Multi-compound and drug-combination pharmacokinetic research on Chinese herbal medicines
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 卷号: 43, 期号: 12, 页码: 3080-3095
作者:
Li, Chuan
;
Jia, Wei-wei
;
Yang, Jun-ling
;
Cheng, Chen
;
Olaleye, Olajide E.
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2024/03/21
Chinese herbal medicine
pharmacokinetics
multi-compound pharmacokinetic research
drug-combination pharmacokinetic research
pharmacokinetic compatibility
Neuroprotective effects of a lead compound from coral via modulation of the orphan nuclear receptor Nurr1
期刊论文
OAI收割
CNS NEUROSCIENCE & THERAPEUTICS, 2022, 页码: 14
作者:
Su, Jian-Wei
;
Yang, Pei
;
Xing, Mei-Mei
;
Chen, Bao
;
Xie, Xia-Hong
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2023/04/10
C
elegans
corals-derived compounds
neuroprotection
Nurr1
SH-SY5Y cells
Integration of offline two-dimensional chromatography and mass defect filtering-based precursor ion list data acquisition for targeted characterization of diterpenoid alkaloids in the lateral roots of Aconitum carmichaelii
期刊论文
OAI收割
JOURNAL OF CHROMATOGRAPHY A, 2022, 卷号: 1684, 页码: 12
作者:
Yu, Yang
;
Yao, Changliang
;
Wei, Wenlong
;
Li, Haojv
;
Huang, Yong
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2022/12/13
Offline two-dimensional chromatography
Mass defect filtering
Precursor ion list
Diterpenoid alkaloids
Aconitum carmichaelii
Disturbed Flow-Facilitated Margination and Targeting of Nanodisks Protect against Atherosclerosis
期刊论文
OAI收割
SMALL, 2022, 页码: 15
作者:
Zhao, Chuan-Rong
;
Li, Jingyi
;
Jiang, Zhi-Tong
;
Zhu, Juan-Juan
;
Zhao, Jia-Nan
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2023/04/10
atherosclerosis
decitabine
endothelial inflammation
hemodynamics
nanoparticles
Cryo-EM structures of cancer-specific helical and kinase domain mutations of PI3K alpha
期刊论文
OAI收割
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2022, 卷号: 119, 期号: 46, 页码: 11
作者:
Liu, Xiao
;
Zhou, Qingtong
;
Hart, Jonathan R.
;
Xu, Yingna
;
Yang, Su
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2023/10/17
phosphoinositide 3-kinase (PI3K)
mass spectrometry
mutants
Anti-infective therapy using species-specific activators of Staphylococcus aureus ClpP
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2022, 卷号: 13, 期号: 1, 页码: 16
作者:
Wei, Bingyan
;
Zhang, Tao
;
Wang, Pengyu
;
Pan, Yihui
;
Li, Jiahui
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2023/04/10
Molecular recognition of morphine and fentanyl by the human mu-opioid receptor
期刊论文
OAI收割
CELL, 2022, 卷号: 185, 期号: 23, 页码: 4361-+
作者:
Zhuang, Youwen
;
Wang, Yue
;
He, Bingqing
;
He, Xinheng
;
Zhou, X. Edward
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2023/04/10