中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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  • 上海药物研究所 [76]
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  • 2019 [76]
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浏览/检索结果: 共76条，第1-10条 帮助

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Discovery of a Highly Selective and Potent kappa Opioid Receptor Agonist from N-Cyclopropylmethyl-7 alpha-phenyl-6,14-endoethanotetrahydronorthebaines with Reduced Central Nervous System (CNS) Side Effects Navigated by the Message-Address Concept 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 24, 页码: 11054-11070
作者:  Xiao, Li;  Wang, Yujun;  Zhang, Mumei;  Wu, Weiwei;  Kong, Linghui
  |  收藏  |  浏览/下载：81/0  |  提交时间：2020/07/01
Common activation mechanism of class A GPCRs 期刊论文  OAI收割
ELIFE, 2019, 卷号: 8, 页码: 31
作者:  Zhou, Qingtong;  Yang, Dehua;  Wu, Meng;  Guo, Yu;  Guo, Wangjing
  |  收藏  |  浏览/下载：76/0  |  提交时间：2020/07/01
Imaging Tumorous Methylglyoxal by an Activatable Near-Infrared Fluorescent Probe for Monitoring Glyoxalase 1 Activity 期刊论文  OAI收割
ANALYTICAL CHEMISTRY, 2019, 卷号: 91, 期号: 24, 页码: 15577-15584
作者:  Ding, Chunyong;  Wang, Fengyang;  Dang, Yijing;  Xu, Zhiai;  Li, Lingling
  |  收藏  |  浏览/下载：25/0  |  提交时间：2020/07/01
Spiroalanfurantones A-D, Four Eudesmanolide-Furan Sesquiterpene Adducts with a Pentacyclic 6/6/5/5/5 Skeleton from Inula helenium 期刊论文  OAI收割
ORGANIC LETTERS, 2019, 卷号: 21, 期号: 23, 页码: 9478-9482
作者:  Cai, You-Sheng;  Wu, Zi;  Wang, Jian-Rong;  Zheng, Xiao-Qin;  Xu, Jie
  |  收藏  |  浏览/下载：18/0  |  提交时间：2020/07/01
A Novel Allosteric Inhibitor of Phosphoglycerate Mutase 1 Suppresses Growth and Metastasis of Non-Small-Cell Lung Cancer 期刊论文  OAI收割
CELL METABOLISM, 2019, 卷号: 30, 期号: 6, 页码: 1107-+
作者:  Huang, Ke;  Liang, Qian;  Zhou, Ye;  Jiang, Lu-lu;  Gu, Wei-ming
  |  收藏  |  浏览/下载：81/0  |  提交时间：2020/07/01
A complex structure of arrestin-2 bound to a G protein-coupled receptor 期刊论文  OAI收割
CELL RESEARCH, 2019, 卷号: 29, 期号: 12, 页码: 971-983
作者:  Yin, Wanchao;  Li, Zhihai;  Jin, Mingliang;  Yin, Yu-Ling;  de Waal, Parker W.
  |  收藏  |  浏览/下载：59/0  |  提交时间：2020/07/01
Mitochondrial Uncoupling Coordinated With PDH Activation Safely Ameliorates Hyperglycemia via Promoting Glucose Oxidation 期刊论文  OAI收割
DIABETES, 2019, 卷号: 68, 期号: 12, 页码: 2197-2209
作者:  Jiang, Haowen;  Jin, Jia;  Duan, Yanan;  Xie, Zhifu;  Li, Yufeng
  |  收藏  |  浏览/下载：31/0  |  提交时间：2020/07/01
3-Deoxy-2 beta,16-dihydroxynagilactone E, a natural compound from Podocarpus nagi, preferentially inhibits JAK2/STAT3 signaling by allosterically interacting with the regulatory domain of JAK2 and induces apoptosis of cancer cells 期刊论文  OAI收割
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 12, 页码: 1578-1586
作者:  Shan, Hui;  Yao, Sheng;  Ye, Yang;  Yu, Qiang
  |  收藏  |  浏览/下载：11/0  |  提交时间：2020/07/01
Celamonols A-D, four triterpenoid and catechin conjugates with immunosuppressive activities from the stems of Celastrus monospermus 期刊论文  OAI收割
ORGANIC CHEMISTRY FRONTIERS, 2019, 卷号: 6, 期号: 22, 页码: 3786-3792
作者:  Qin, Jun-Jun;  Fu, Yi-Fan;  Chen, Xi
  |  收藏  |  浏览/下载：17/0  |  提交时间：2020/07/01
Synthesis and Biological Evaluation of Five-Atom-Linker-Based Arylpiperazine Derivatives with an Atypical Antipsychotic Profile 期刊论文  OAI收割
CHEMMEDCHEM, 2019, 页码: 11
作者:  Wu, Chunhui;  Wang, Yu;  Yang, Feipu;  Shi, Wenqiang;  Wang, Zhen
  |  收藏  |  浏览/下载：28/0  |  提交时间：2020/07/01