中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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  • 上海药物研究所 [10]
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  • 2019 [10]
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浏览/检索结果: 共10条，第1-10条 帮助

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Discovery and biological evaluation of vinylsulfonamide derivatives as highly potent, covalent TEAD autopalmitoylation inhibitors 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 184, 页码: 15
作者:  Lu, Wenchao;  Wang, Jun;  Li, Yong;  Tao, Hongru;  Xiong, Huan
  |  收藏  |  浏览/下载：83/0  |  提交时间：2020/07/01
Sodium oligomannate therapeutically remodels gut microbiota and suppresses gut bacterial amino acids-shaped neuroinflammation to inhibit Alzheimer's disease progression 期刊论文  OAI收割
CELL RESEARCH, 2019, 卷号: 29, 期号: 10, 页码: 787-803
作者:  Wang, Xinyi;  Sun, Guangqiang;  Feng, Teng;  Zhang, Jing;  Huang, Xun
  |  收藏  |  浏览/下载：84/0  |  提交时间：2020/07/01
Structure-Based Discovery and Development of a Series of Potent and Selective Bromodomain and Extra-Terminal Protein Inhibitors 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 18, 页码: 8642-8663
作者:  Hu, Jianping;  Tian, Chang-Qing;  Damaneh, Mohammadali Soleimani;  Li, Yanlian;  Cao, Danyan
  |  收藏  |  浏览/下载：36/0  |  提交时间：2020/07/01
Increased PARP1-DNA binding due to autoPARylation inhibition of PARP1 on DNA rather than PARP1-DNA trapping is correlated with PARP1 inhibitor's cytotoxicity 期刊论文  OAI收割
INTERNATIONAL JOURNAL OF CANCER, 2019, 卷号: 145, 期号: 3, 页码: 714-727
作者:  Chen, Hua-Dong
  |  收藏  |  浏览/下载：7/0  |  提交时间：2024/03/21
Inhibition of the BET family reduces its new target gene IDO1 expression and the production of L-kynurenine 期刊论文  OAI收割
CELL DEATH & DISEASE, 2019, 卷号: 10, 页码: 13
作者:  Tian, Chang-Qing;  Chen, Lin;  Chen, Hua-Dong;  Huan, Xia-Juan;  Hu, Jian-Ping
  |  收藏  |  浏览/下载：6/0  |  提交时间：2020/07/01
Increased PARP1-DNA binding due to autoPARylation inhibition of PARP1 on DNA rather than PARP1-DNA trapping is correlated with PARP1 inhibitor's cytotoxicity 期刊论文  OAI收割
CANCER RESEARCH, 2019, 卷号: 79, 期号: 13, 页码: 2
作者:  Chen, Hua-Dong;  Chen, Chuan-Huizi;  Wang, Yu-Ting;  Guo, Ne;  Tian, Yu-Nan
  |  收藏  |  浏览/下载：19/0  |  提交时间：2020/07/01
Exploration of the hepatoprotective chemical base of an orally administered herbal formulation (YCHT) in normal and CCl4-intoxicated liver injury rats. Part 1: Metabolic profiles from the liver-centric perspective 期刊论文  OAI收割
JOURNAL OF ETHNOPHARMACOLOGY, 2019, 卷号: 237, 页码: 81-91
作者:  Liu, Huan;  Chen, Mingcang;  Yin, Hao;  Hu, Pei;  Wang, Yangyang
  |  收藏  |  浏览/下载：13/0  |  提交时间：2020/07/01
Exploration of the hepatoprotective chemical base of an orally administered herbal formulation (YCHT) in normal and CCl4-intoxicated liver injury rats. Part 2: Hepatic disposition in vivo and hepatoprotective activity in vitro 期刊论文  OAI收割
JOURNAL OF ETHNOPHARMACOLOGY, 2019, 卷号: 236, 页码: 161-172
作者:  Tian, Xiaoting;  Liu, Huan;  Qiao, Shida;  Yin, Hao;  Chen, Mingcang
  |  收藏  |  浏览/下载：9/0  |  提交时间：2020/07/01
Effective cancer immunotherapy by Ganoderma lucidum polysaccharide-gold nanocomposites through dendritic cell activation and memory T cell response 期刊论文  OAI收割
Carbohydrate Polymers, 2019, 卷号: 205, 页码: 192-202
作者:  Zhang, Shulei;  Pang, Guibin;  Chen, Chao;  Qin, Jianzhong;  Yu, Huan
  |  收藏  |  浏览/下载：55/0  |  提交时间：2019/01/08
Cytotoxic Nitrogenous Terpenoids from Two South China Sea Nudibranchs Phyllidiella pustulosa, Phyllidia coelestis, and Their Sponge-Prey Acanthella cavernosa 期刊论文  OAI收割
MARINE DRUGS, 2019, 卷号: 17, 期号: 1, 页码: 56
作者:  Wu, Qihao;  Chen, Wen-Ting;  Li, Song-Wei;  Ye, Jian-Yu;  Huan, Xia-Juan
  |  收藏  |  浏览/下载：14/0  |  提交时间：2024/03/21