中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [13]
采集方式
OAI收割 [13]
内容类型
期刊论文 [13]
发表日期
2020 [13]
学科主题
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浏览/检索结果:
共13条,第1-10条
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发表日期:2020
专题:上海药物研究所
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SAF-189s, a potent new-generation ROS1 inhibitor, is active against crizotinib-resistant ROS1 mutant-driven tumors
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 7
作者:
Xia, Zong-jun
;
Ji, Yin-chun
;
Sun, De-qiao
;
Peng, Xia
;
Gao, Ying-lei
  |  
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2020/12/21
ROS1 kinase
ROS1 inhibitor
SAF-189s
lorlatinib
crizotinib resistance
G2032R mutant
NSCLC
Activation of unfolded protein response overcomes Ibrutinib resistance in diffuse large B-cell lymphoma
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 10
作者:
Zhang, Xiao-tuan
;
Hu, Xiao-bei
;
Wang, Han-lin
;
Kan, Wei-juan
;
Xu, Lei
  |  
收藏
  |  
浏览/下载:75/0
  |  
提交时间:2020/12/24
DLBCL
BTK inhibitor
ibrutinib resistance
UPR
TUDCA
2-DG
A novel M phase blocker, DCZ3301 enhances the sensitivity of bortezomib in resistant multiple myeloma through DNA damage and mitotic catastrophe
期刊论文
OAI收割
Journal of Experimental & Clinical Cancer Research, 2020, 卷号: 39, 期号: 1
作者:
Hu,Liangning
;
Li,Bo
;
Chen,Gege
;
Song,Dongliang
;
Xu,Zhijian
  |  
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2020/07/01
Multiple myeloma
Drug-resistance
DNA damage response
Cell cycle
Three new bisflavonols from the seeds of Hovenia dulcis Thunb. and their anti-RSV activities
期刊论文
OAI收割
FITOTERAPIA, 2020, 卷号: 143, 页码: 6
作者:
Xu, Fangfang
;
Gao, Meihua
;
Li, Hua
;
Han, Xiaodong
;
Zhang, Xiaoqi
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2020/07/01
Hovenia dulcis Thunb.
Bisflavonol
Flavonoids
Anti-RSV activity
Synthesis and biological evaluation of heterocyclic bis-aryl amides as novel Src homology 2 domain containing protein tyrosine phosphatase-2 (SHP2) inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 11, 页码: 5
作者:
Satheeshkumar, Rajendran
;
Zhu, Rui
;
Feng, Bo
;
Huang, Chao
  |  
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2020/07/01
Heterocyclic bis-aryl amides
PTP1B
SHP2
Inhibitors
Structure-activity relationships (SAR)
A novel phosphoramide compound, DCZ0847, displays in vitro and in vivo anti-myeloma activity, alone or in combination with bortezomib
期刊论文
OAI收割
CANCER LETTERS, 2020, 卷号: 478, 页码: 45-55
作者:
Chen, Gege
;
Hu, Ke
;
Sun, Haiguo
;
Zhou, Jinfeng
;
Song, Dongliang
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2020/07/01
Multiple myeloma
Bone marrow microenvironment
DNA damage
JAK2/STAT3 pathway
Discovery of a Potent and Selective NF-kappa B-Inducing Kinase (NIK) Inhibitor That Has Anti-inflammatory Effects in Vitro and in Vivo
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 8, 页码: 4388-4407
作者:
Li, Zhiqiang
;
Li, Xinzhi
;
Su, Ming-Bo
;
Gao, Li-Xin
;
Zhou, Yu-Bo
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2020/07/01
A novel silicone derivative of natural osalmid (DCZ0858) induces apoptosis and cell cycle arrest in diffuse large B-cell lymphoma via the JAK2/STAT3 pathway
期刊论文
OAI收割
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2020, 卷号: 5, 期号: 1, 页码: 11
作者:
Lu, Kang
;
Li, Bo
;
Zhang, Hui
;
Xu, Zhijian
;
Song, Dongliang
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2020/07/01
Supramolecular Prodrug Nanovectors for Active Tumor Targeting and Combination Immunotherapy of Colorectal Cancer
期刊论文
OAI收割
ADVANCED SCIENCE, 2020, 页码: 14
作者:
Hu, Xianli
;
Hou, Bo
;
Xu, Zhiai
;
Saeed, Madiha
;
Sun, Fang
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2020/07/01
active tumor targeting
cancer management
colorectal cancer
combination immunotherapy
photodynamic immunotherapy
prodrugs
supramolecular nanovectors
Antitumor effects of rafoxanide in diffuse large B cell lymphoma via the PTEN/PI3K/Akt and JNK/c-Jun pathways
期刊论文
OAI收割
LIFE SCIENCES, 2020, 卷号: 243, 页码: 11
作者:
He, Wan
;
Xu, Zhijian
;
Song, Dongliang
;
Zhang, Hui
;
Li, Bo
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2020/07/01
Diffuse large B-cell lymphoma
Rafoxanide
PTEN/PI3K/AKT
Apoptosis
DNA damage