机构

• 上海药物研究所 [14]

采集方式

• OAI收割 [14]

内容类型

• 期刊论文 [14]

发表日期

• 2021 [14]

学科主题

筛选

浏览/检索结果: 共14条，第1-10条 帮助 限定条件 发表日期：2021    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序题名升序题名降序作者升序作者降序发表日期升序发表日期降序 Requirments for primary human hepatocyte 期刊论文  OAI收割 CELL PROLIFERATION, 2021, 页码: 6 作者:  Peng, Zhaoliang;  Wu, Jiaying;  Hu, Shijun;  Ma, Aijin;  Wang, Lei   |  收藏  |  浏览/下载：31/0  |  提交时间：2022/06/15 primary human hepatocyte  quality control  standard   Discovery and Development of a Potent, Selective, and Orally Bioavailable CHK1 Inhibitor Candidate: 5-((4-((3-Amino-3-methylbutyl)amino)-5-(trifluoromethyl)pyrimidin-2-yl)amino)picolinonitrile 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 20, 页码: 15069-15090 作者:  Jin, Tingting;  Xu, Lei;  Wang, Peipei;  Hu, Xiaobei;  Zhang, Runyuan   |  收藏  |  浏览/下载：27/0  |  提交时间：2022/01/04 Synthesis and Evaluation of 3-(Indol-3-yl)-4-(Pyrazolo[3,4-c]Pyridazin-3-yl)-Maleimides as Potent Mutant Isocitrate Dehydrogenase-1 Inhibitors 期刊论文  OAI收割 PHARMACEUTICAL CHEMISTRY JOURNAL, 2021, 卷号: 55, 期号: 7, 页码: 655-664 作者:  Xu, Jianghong;  Hu, Yuanyuan;  Liu, Xiaoqi;  Gao, Anhui;  Gao, Lixin   |  收藏  |  浏览/下载：47/0  |  提交时间：2021/12/01 IDH1-R132H inhibitors  synthesis  biological activity  docking  3-(indol-3-yl)-4-(pyrazolo-[3  4-c]pyridazin-3-yl)-maleimides   Competitive CatSper Activators of Progesterone from Rhynchosia volubilis 期刊论文  OAI收割 PLANTA MEDICA, 2021, 页码: 10 作者:  Xiang, Jin;  Kang, Hang;  Li, Hong-Gang;  Shi, Yu-Long;  Zhang, Ya-Li   |  收藏  |  浏览/下载：47/0  |  提交时间：2021/11/04 Leguminosae  Rhynchosia volubilis  CatSper  prenylated isoflavonoids  rhynchones A - E   Systematic investigation on the anti-rheumatoid arthritis material basis and mechanism of Juan Bi Tang. Part 1: Integrating metabolic profiles and network pharmacology 期刊论文  OAI收割 JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2021, 卷号: 202, 页码: 11 作者:  Li, Jiajia;  Li, Lei;  Wang, Yangyang;  Zhao, Yuxuan;  Hu, Pei   |  收藏  |  浏览/下载：51/0  |  提交时间：2021/08/17 Juanbi-Tang (JBT)  Rheumatoid arthritis (RA)  Metabolites  Mass  Network pharmacology  Molecular docking   Acylphloroglucinol derivatives with ATP citrate lyase inhibitory activities from Syzygium oblatum Wall 期刊论文  OAI收割 PHYTOCHEMISTRY, 2021, 卷号: 187, 页码: 7 作者:  Huang, Jin-Chang;  Liu, Yi-Nan;  Tao, Yun-Hua;  Chen, Bai-Yu;  Lei, Chun   |  收藏  |  浏览/下载：29/0  |  提交时间：2021/08/17 Syzygium oblatum Wall  Myrtaceae  Acylphloroglucinols  Oblatones A-I  ATP citrate lyase   SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damages and constitutes an antiviral target 期刊论文  OAI收割 CELL RESEARCH, 2021, 页码: 14 作者:  Xia, Bingqing;  Shen, Xurui;  He, Yang;  Pan, Xiaoyan;  Liu, Feng-Liang   |  收藏  |  浏览/下载：75/0  |  提交时间：2021/08/17 Discovery of thalidomide-based PROTAC small molecules as the highly efficient SHP2 degraders 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 218, 页码: 14 作者:  Yang, Xiangbo;  Wang, Zhijia;  Pei, Yuan;  Song, Ning;  Xu, Lei   |  收藏  |  浏览/下载：29/0  |  提交时间：2021/08/17 SHP2 degradation  Proteolysis targeting chimera (PROTAC)  Thalidomide-based heterobifunctional molecules  E3 ubiquitin ligase  CRBN   An integrative drug repositioning framework discovered a potential therapeutic agent targeting COVID-19 期刊论文  OAI收割 SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2021, 卷号: 6, 期号: 1, 页码: 16 作者:  Ge, Yiyue;  Tian, Tingzhong;  Huang, Suling;  Wan, Fangping;  Li, Jingxin   |  收藏  |  浏览/下载：28/0  |  提交时间：2022/06/15 Downregulation of c-Myc expression confers sensitivity to CHK1 inhibitors in hematologic malignancies 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9 作者:  Jiang, Kai-long;  Tong, Le-xian;  Wang, Tao;  Wang, Han-lin;  Hu, Xiao-bei   |  收藏  |  浏览/下载：49/0  |  提交时间：2021/05/24 CHK1 inhibitors  PY34  drug sensitivity  c-Myc  hematologic malignancies