中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [25]
采集方式
OAI收割 [25]
内容类型
期刊论文 [25]
发表日期
2023 [25]
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发表日期:2023
专题:上海药物研究所
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Discovery of 5-trifluoromethyl-2-aminopyrimidine derivatives as potent dual inhibitors of FLT3 and CHK1
期刊论文
OAI收割
RSC MEDICINAL CHEMISTRY, 2023, 页码: 14
作者:
Deng, Minjie
;
Gao, Yue
;
Wang, Peipei
;
Du, Wenjing
;
Xu, Gaoya
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/02/19
Single-cell RNA sequencing reveals a hierarchical transcriptional regulatory network of terpenoid biosynthesis in cotton secretory glandular cells
期刊论文
OAI收割
MOLECULAR PLANT, 2023, 卷号: 16, 期号: 12, 页码: 1990-2003
作者:
Lin, Jia-Ling
;
Chen, Longxian
;
Wu, Wen-Kai
;
Guo, Xiao-Xiang
;
Yu, Cheng-Hui
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/01/26
Berberine derivative DCZ0358 induce oxidative damage by ROS-mediated JNK signaling in DLBCL cells
期刊论文
OAI收割
INTERNATIONAL IMMUNOPHARMACOLOGY, 2023, 卷号: 125, 页码: 15
作者:
Feng, Qilin
;
Hu, Ke
;
Hu, Huifang
;
Lu, Yumeng
;
Zhang, Hui
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2024/01/16
DLBCL
ROS
DNA damage
JNK
Mitochondrial dysfunction
Dihydrocelastrol induces antitumor activity and enhances the sensitivity of bortezomib in resistant multiple myeloma by inhibiting STAT3-dependent PSMB5 regulation
期刊论文
OAI收割
ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2023, 卷号: 55, 期号: 12, 页码: 1884-1891
作者:
Jin, Shuhan
;
Li, Bo
;
Zhang, Bibo
;
Gao, Xuejie
;
Jia, Xinyan
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/02/27
dihydrocelastrol
multiple myeloma
JAK2/STAT3
PSMB5
bortezomib resistance
The novel norcantharidin derivative DCZ5417 suppresses multiple myeloma progression by targeting the TRIP13-MAPK-YWHAE signaling pathway
期刊论文
OAI收割
JOURNAL OF TRANSLATIONAL MEDICINE, 2023, 卷号: 21, 期号: 1, 页码: 17
作者:
Wang, Yingcong
;
Dong, Sanfeng
;
Hu, Ke
;
Xu, Li
;
Feng, Qilin
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2024/01/26
Norcantharidin
Derivative
DCZ5417
TRIP13
Anti-myeloma
MAPK
An integrative profiling of metabolome and transcriptome in the plasma and skeletal muscle following an exercise intervention in diet-induced obese mice
期刊论文
OAI收割
JOURNAL OF MOLECULAR CELL BIOLOGY, 2023, 卷号: 15, 期号: 3, 页码: 14
作者:
Han, Shuang
;
Wu, Qingqian
;
Wang, Mengying
;
Yang, Miqi
;
Sun, Chen
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/12/08
type 2 diabetes
exercise intervention
metabolomics
transcriptomics
GPCR activation and GRK2 assembly by a biased intracellular agonist
期刊论文
OAI收割
NATURE, 2023, 页码: 27
作者:
Duan, Jia
;
Liu, Heng
;
Zhao, Fenghui
;
Yuan, Qingning
;
Ji, Yujie
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2023/10/17
Novel thieno[2,3-b]quinoline-procaine hybrid molecules: A new class of allosteric SHP-1 activators evolved from PTP1B inhibitors
期刊论文
OAI收割
CHINESE CHEMICAL LETTERS, 2023, 卷号: 34, 期号: 8, 页码: 6
作者:
Xu, Lei
;
Xuyan, Xuyang
;
Minmi, Minmin
;
Wang, Zhiji
;
Shee, Chao
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2023/10/17
Activator
PTPs
Inhibitor
Thieno[2
b ]quinoline derivatives
Diffuse large B-cell lymphoma
Dual ligands relay-promoted transformation of unstrained ketones to polyfluoroarenes and nitriles
期刊论文
OAI收割
SCIENCE CHINA-CHEMISTRY, 2023, 卷号: 66, 期号: 7, 页码: 2037-2045
作者:
Wang, Zhen-Yu
;
Xu, Huiying
;
Zhang, Xu
;
Wang, Xing
;
Xu, Hui
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2023/10/17
C-C bond activation
dual ligands relay
unstrained ketones
modification of drugs and natural products
DFT study
Chloroquine enhances the efficacy of chemotherapy drugs against acute myeloid leukemia by inactivating the autophagy pathway
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 11
作者:
Wang, Han-lin
;
Li, Jia-nan
;
Kan, Wei-juan
;
Xu, Gao-ya
;
Luo, Guang-hao
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2023/10/17
acute myeloid leukemia
cytarabine
daunorubicin
idarubicin
drug resistant
multi-omics
autophagy
chloroquine phosphate