机构

• 上海药物研究所 [33]
• 大连化学物理研究所 [1]
• 上海生物化学与细胞生... [1]
• 上海营养与健康研究所 [1]
• 合肥物质科学研究院 [1]

采集方式

• OAI收割 [37]

内容类型

• 期刊论文 [37]

发表日期

• 2024 [1]
• 2023 [4]
• 2022 [7]
• 2021 [3]
• 2020 [5]
• 2019 [2]
• 更多

学科主题

• Biochemist... [1]
• Oncology [1]
• Research &... [1]

筛选

浏览/检索结果: 共37条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Discovery of a brain-permeable bromodomain and extra terminal domain (BET) inhibitor with selectivity for BD1 for the treatment of multiple sclerosis 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 265, 页码: 14 作者:  Chen, Xuetao;  Wu, Tingting;  Du, Zhiyan;  Kang, Wenjing;  Xu, Rujun   |  收藏  |  浏览/下载：24/0  |  提交时间：2024/02/27 BET  BD1  Bromodomain  Brain-permeable  Multiple sclerosis   Design, Construction, and Screening of Diversified Pyrimidine-Focused DNA-Encoded Libraries 期刊论文  OAI收割 ACS MEDICINAL CHEMISTRY LETTERS, 2023, 卷号: 14, 期号: 8, 页码: 1073-1078 作者:  Seydimemet, Mengnisa;  Yang, Yixuan;  Lv, Yuhan;  Liu, Jiaxiang;  Yan, Ziqin   |  收藏  |  浏览/下载：14/0  |  提交时间：2023/10/17 DNA-encoded library technology  Pyrimidine-focusedDNA-encodedlibrary  BRD4  Affinity screening  Inhibitor   Discovery of 1H-Imidazo[4,5-b]pyridine Derivatives as Potent and Selective BET Inhibitors for the Management of Neuropathic Pain 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 13, 页码: 8725-8744 作者:  Chen, Xuetao;  Cao, Danyan;  Liu, Chihong;  Meng, Fanying;  Zhang, Zijian   |  收藏  |  浏览/下载：9/0  |  提交时间：2023/10/17 Selective degradation of cellular BRD3 and BRD4-L promoted by PROTAC molecules in six cancer cell lines 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 254, 页码: 17 作者:  Yan, Ziqin;  Lyu, Xilin;  Lin, Dongze;  Wu, Gaoxing;  Gong, Yang   |  收藏  |  浏览/下载：29/0  |  提交时间：2023/10/17 Design, synthesis, and biological evaluation of BRD4 degraders 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 78, 页码: 12 作者:  Ding, Mengyuan;  Shao, Yingying;  Sun, Danwen;  Meng, Suorina;  Zang, Yi   |  收藏  |  浏览/下载：19/0  |  提交时间：2023/04/10 PROTAC  BRD4 degradation  Leukemia  Multiple myeloma  Pulmonary fibrosis   In-situ clickable prodrug nanoplatform locally activates T lymphocytes to potentiate cancer immunotherapy 期刊论文  OAI收割 NANO TODAY, 2022, 卷号: 47, 页码: 11 作者:     |  收藏  |  浏览/下载：32/0  |  提交时间：2023/04/10 Immune-excluded tumor  Extracellular matrix  In-situ click reaction  Prodrug nanoparticles  Immune resistance   Design and development of a novel series of oral bivalent BET inhibitors with potent anticancer activities 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 239, 页码: 13 作者:  Luo, Menglan;  Wu, Qian;  Yang, Yueyue;  Sun, Lin;  Huan, Xiajuan   |  收藏  |  浏览/下载：40/0  |  提交时间：2022/08/30 BET inhibitor  BRD4  Bivalent inhibitor  Anticancer   Phosphoproteomics Reveals the AMPK Substrate Network in Response to DNA Damage and Histone Acetylation 期刊论文  OAI收割 GENOMICS PROTEOMICS & BIOINFORMATICS, 2022, 卷号: 20, 期号: 4, 页码: 597-613 作者:  Jiang, Yuejing;  Cong, Xiaoji;  Jiang, Shangwen;  Dong, Ying;  Zhao, Lei   |  收藏  |  浏览/下载：15/0  |  提交时间：2023/04/10 AMPK  Phosphoproteomics  Histone modification  DNA damage  Apoptosis   Adjusted degradation of BRD4 S and BRD4 L based on fine structural modifications of the pyrrolopyridone scaffold 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 236, 页码: 14 作者:  Chen, Jingjing;  He, Huixin;  Wei, Aihuan;  Li, Yalei;  Cheng, Gang   |  收藏  |  浏览/下载：23/0  |  提交时间：2022/08/16 PROTAC  Pyrrolopyridone  BRD4 S  Selectivity   BRD4 Targets the KEAP1-Nrf2-G6PD Axis and Suppresses Redox Metabolism in Small Cell Lung Cancer 期刊论文  OAI收割 ANTIOXIDANTS, 2022, 卷号: 11 作者:  Lv, Yang;  Lv, Xiaotong;  Zhang, Jiahui;  Cao, Guozhen;  Xu, Changzhi   |  收藏  |  浏览/下载：59/0  |  提交时间：2022/05/16 small cell lung cancer  BRD4  KEAP1  Nrf2  pentose phosphate pathway